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Aceon

Generic Name: perindopril (per-IN-doe-pril)
Brand Name: Aceon

This drug may cause injury or death to the fetus if used during pregnancy. If you think you may be pregnant, contact your doctor right away. If you are planning to become pregnant, talk with your doctor about other treatment options.


Aceon is used for:

Treating high blood pressure. It may be used alone or along with other medicines. It is also used to reduce the risk of heart attack or death caused by heart problems in patients with stable coronary artery disease. It may also be used to treat other conditions as determined by your doctor.

Aceon is an angiotensin-converting enzyme (ACE) inhibitor. It works by relaxing blood vessels. This helps to lower blood pressure.

Do NOT use Aceon if:

  • you are allergic to any ingredient in Aceon
  • you are pregnant
  • you have a history of angioedema (swelling of the hands, face, lips, eyes, throat, or tongue; difficulty swallowing or breathing; or hoarseness), including angioedema caused by treatment with an ACE inhibitor (eg, lisinopril)
  • you have severe kidney problems
  • you are taking a medicine that contains aliskiren and you also have diabetes or kidney problems. Check with your doctor or pharmacist if you are not sure if a medicine you take contains aliskiren

Contact your doctor or health care provider right away if any of these apply to you.

Before using Aceon:

Some medical conditions may interact with Aceon. Tell your doctor or pharmacist if you have any medical conditions, especially if any of the following apply to you:

  • if you are pregnant, planning to become pregnant, or are breast-feeding
  • if you are able to become pregnant
  • if you are taking any prescription or nonprescription medicine, herbal preparation, or dietary supplement
  • if you have allergies to medicines, foods, or other substances
  • if you have a history of heart problems (eg, heart failure), blood vessel problems (eg, brain or heart blood vessels), bone marrow problems, liver problems, diabetes, or kidney problems (eg, renal artery stenosis)
  • if you have a history of a stroke or kidney transplant
  • if you have an autoimmune disease (eg, lupus, scleroderma)
  • if you are dehydrated or have low blood volume
  • if you have high blood potassium levels, low blood sodium levels, or are on a low-salt (sodium) diet
  • if you are on dialysis or are scheduled to have surgery or receive anesthesia

Some MEDICINES MAY INTERACT with Aceon. Tell your health care provider if you are taking any other medicines, especially any of the following:

  • Cyclosporine, eplerenone, potassium-sparing diuretics (eg, spironolactone, triamterene), potassium supplements, or trimethoprim because the risk of high blood potassium levels may be increased
  • Everolimus or sirolimus because the risk of angioedema may be increased
  • Aliskiren or angiotensin receptor blockers (eg, valsartan) because the risk of certain side effects (eg, kidney problems, high blood potassium levels, low blood pressure) may be increased
  • Gold-containing medicines (eg, auranofin) because flushing, nausea, vomiting, and low blood pressure may occur
  • Dextran sulfate or diuretics (eg, furosemide, hydrochlorothiazide) because they may increase the risk of Aceon's side effects
  • Nonsteroidal anti-inflammatory drugs (NSAIDs) (eg, celecoxib, ibuprofen, indomethacin) because they may increase the risk of kidney problems and decrease Aceon's effectiveness
  • Lithium or sulfonylureas (eg, glyburide) because the risk of their side effects may be increased by Aceon

This may not be a complete list of all interactions that may occur. Ask your health care provider if Aceon may interact with other medicines that you take. Check with your health care provider before you start, stop, or change the dose of any medicine.

How to use Aceon:

Use Aceon as directed by your doctor. Check the label on the medicine for exact dosing instructions.

  • Take Aceon by mouth with or without food.
  • Take Aceon on a regular schedule to get the most benefit from it.
  • Taking Aceon at the same time(s) each day will help you to remember to take it.
  • Continue taking Aceon even if you feel well. Do not miss any doses.
  • If you miss a dose of Aceon, take it as soon as possible. If it is almost time for your next dose, skip the missed dose and go back to your regular dosing schedule. Do not take 2 doses at once.

Ask your health care provider any questions you may have about how to use Aceon.

Important safety information:

  • Aceon may cause dizziness or light-headedness. These effects may be worse if you take it with alcohol or certain medicines. Use Aceon with caution. Do not drive or perform other possibly unsafe tasks until you know how you react to it.
  • Aceon may cause dizziness, light-headedness, or fainting; alcohol, hot weather, exercise, or fever may increase these effects. To prevent them, sit up or stand slowly, especially in the morning. Sit or lie down at the first sign of any of these effects. Avoid sudden changes in posture.
  • Drink plenty of fluids while taking Aceon and avoid engaging in activities that cause excessive sweating. Dehydration, excessive sweating, vomiting, or diarrhea may increase the risk of low blood pressure. Contact your health care provider at once if any of these occur.
  • A persistent, unproductive cough may occur. Tell your doctor if this occurs. If caused by Aceon, this type of cough generally recovers after Aceon is stopped.
  • Patients who take medicine for high blood pressure often feel tired or run down for a few weeks after starting treatment. Be sure to take your medicine even if you may not feel "normal." Tell your doctor if you develop any new symptoms.
  • Aceon may cause a serious side effect called angioedema. Contact your doctor at once if you develop swelling of the hands, face, lips, eyes, throat, or tongue; difficulty swallowing or breathing; or hoarseness.
  • Aceon may not work as well in black patients. They may also be at greater risk of side effects. Contact your doctor if your symptoms do not improve or if they become worse.
  • Tell your doctor or dentist that you take Aceon before you receive any medical or dental care, emergency care, or surgery.
  • Rarely, Aceon may lower the ability of your body to fight infection. This risk may be greater if you have certain other health problems (eg, kidney problems, collagen vascular disease). Avoid contact with people who have colds or infections. Tell your doctor if you notice signs of infection like fever, sore throat, rash, or chills.
  • Check with your doctor before you use a salt substitute or a product that has potassium in it.
  • If you have high blood pressure, do not use nonprescription products that contain stimulants. These products may include diet pills or cold medicines. Contact your doctor if you have any questions or concerns.
  • Lab tests, including liver function, kidney function, blood pressure, and blood electrolyte levels, may be performed while you use Aceon. These tests may be used to monitor your condition or check for side effects. Be sure to keep all doctor and lab appointments.
  • Use Aceon with caution in the ELDERLY; they may be more sensitive to its effects, especially dizziness and rash.
  • Aceon should be used with extreme caution in CHILDREN; safety and effectiveness in children have not been confirmed.
  • PREGNANCY and BREAST-FEEDING: Aceon may cause birth defects or fetal or newborn death if you take it while you are pregnant. If you think you may be pregnant, contact your doctor right away. It is not known if this medicine is found in breast milk. If you are or will be breast-feeding while you use Aceon, check with your doctor. Discuss any possible risks to your baby.

Possible side effects of Aceon:

All medicines may cause side effects, but many people have no, or minor, side effects. Check with your doctor if any of these most COMMON side effects persist or become bothersome:

Arm or leg pain; back pain; cough; diarrhea; dizziness; headache; runny nose; weakness.

Seek medical attention right away if any of these SEVERE side effects occur:

Severe allergic reactions (rash; hives; itching; difficulty breathing; tightness in the chest; swelling of the mouth, face, lips, eyes, throat, or tongue; hoarseness); chest pain; confusion; decreased, difficult, or painful urination; depression; difficulty swallowing; fast, slow, or irregular heartbeat; fever, chills, or sore throat; numbness of an arm or leg; one-sided weakness; prolonged or severe nausea, vomiting, or diarrhea; stomach pain (with or without nausea or vomiting); sudden, severe headache; swelling of the hands, legs, or trunk; symptoms of liver problems (eg, dark urine, loss of appetite, pale stools, yellowing of the skin or eyes); symptoms of low blood pressure (eg, fainting, severe dizziness, light-headedness); unusual tiredness or weakness; vision or speech problems.

This is not a complete list of all side effects that may occur. If you have questions about side effects, contact your health care provider. Call your doctor for medical advice about side effects. To report side effects to the appropriate agency, please read the Guide to Reporting Problems to FDA.

If OVERDOSE is suspected:

Contact 1-800-222-1222 (the American Association of Poison Control Centers), your local poison control center, or emergency room immediately. Symptoms may include fainting; severe dizziness or light-headedness; weakness.

Proper storage of Aceon:

Store Aceon at room temperature, between 68 and 77 degrees F (20 and 25 degrees C). Store away from heat, light, and moisture. Do not store in the bathroom. Keep Aceon out of the reach of children and away from pets.

General information:

  • If you have any questions about Aceon, please talk with your doctor, pharmacist, or other health care provider.
  • Aceon is to be used only by the patient for whom it is prescribed. Do not share it with other people.
  • If your symptoms do not improve or if they become worse, check with your doctor.
  • Check with your pharmacist about how to dispose of unused medicine.

This information should not be used to decide whether or not to take Aceon or any other medicine. Only your health care provider has the knowledge and training to decide which medicines are right for you. This information does not endorse any medicine as safe, effective, or approved for treating any patient or health condition. This is only a brief summary of general information about Aceon. It does NOT include all information about the possible uses, directions, warnings, precautions, interactions, adverse effects, or risks that may apply to Aceon. This information is not specific medical advice and does not replace information you receive from your health care provider. You must talk with your healthcare provider for complete information about the risks and benefits of using Aceon.

Review Date: August 8, 2016

Disclaimer: This information should not be used to decide whether or not to take this medicine or any other medicine. Only your health care provider has the knowledge and training to decide which medicines are right for you. This information does not endorse any medicine as safe, effective, or approved for treating any patient or health condition. This is only a brief summary of general information about this medicine. It does NOT include all information about the possible uses, directions, warnings, precautions, interactions, adverse effects, or risks that may apply to this medicine. This information is not specific medical advice and does not replace information you receive from your health care provider. You must talk with your healthcare provider for complete information about the risks and benefits of using this medicine.

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