Enlarged Prostate (BPH) medications and Alcohol Interactions
Medically reviewed by L. Anderson, PharmD Last updated on Nov 7, 2017.
The prostate gland is a small gland that is part of the male reproductive tract found below the bladder and in front of the rectum. Benign prostatic hyperplasia (BPH) is a male condition in which the prostate gland grows larger than normal, but it is not cancerous. This gland produces a fluid that mixes with sperm to make semen.
Drug Classes Used for BPH:
When combined with alcohol, alpha blockers like tamsulosin (Flomax) and silodosin (Rapaflo) may increase the risk of low blood pressure and possible fainting upon standing (orthostatic hypotension). Headache, dizziness, lightheadedness, fainting, and/or changes in pulse or heart rate may occur. These effects may be most common at the beginning of treatment, when a dose is increased, or when treatment is restarted after an interruption. Jalyn, a combination alpha blocker (tamsulosin) and 5-alpha-reductase inhibitor (dutasteride) is also available for BPH treatment, and may have a similar interaction.
Tadalafil (Cialis), a 5-alpha-reductase inhibitor (PDE5 inhibitor) used for erectile dysfunction, is also approved for treatment of BPH and can have an additive effect to lower blood pressure when combined with alcohol. You may also experience symptoms such as dizziness, lightheadedness, fainting, flushing, headache, and heart palpitations with this drug. These effects may be more prominent at the beginning of therapy. Avoid or limit use of alcohol with tadalafil treatment.
5-alpha-reductase inhibitors such as finasteride (Proscar) and dutasteride (Avodart) prevent the conversion of testosterone to dihydrotestosterone (DHT) in the body. DHT is involved in the development of benign prostatic hyperplasia (BPH). In product labeling, these drugs are not noted to interact with alcohol.
Common Benign Prostatic Hyperplasia Medications
|Generic Name||Common Brand Names|
|doxazosin||Cardura, Cardura XL|
|dutasteride and tamsulosin||Jalyn|
*Note: This is not a complete drug list; always check with your pharmacist for possible drug-alcohol interactions.
Types of Drug Interactions With Alcohol
- Acne Medicines and Alcohol
- ADHD Medications and Alcohol
- Allergies, Cough/Cold Medications and Alcohol
- Antibiotic Medications and Alcohol
- Antidepressant Medications and Alcohol
- Antipsychotic Medications and Alcohol
- Anxiety Medications and Alcohol
- Bipolar Medications and Alcohol
- Birth Control Medications and Alcohol
- Blood Thinners and Alcohol
- Caffeine, Energy Drinks and Alcohol
- Cholesterol Medications and Alcohol
- Diabetes Medications and Alcohol
- Erectile Dysfunction Medications and Alcohol
- Heart Medications and Alcohol
- Herbal Supplements and Alcohol
- Illicit Drugs and Alcohol
- Motion Sickness Medications and Alcohol
- Muscle Relaxants and Alcohol
- Pain / Fever Medications and Alcohol
- Seizure Medications and Alcohol
- Sleep (Insomnia) Medications and Alcohol
- Stomach / Heartburn Medications and Alcohol
- Weight Loss Drugs and Alcohol
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.