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Jalyn

Generic name: dutasteride and tamsulosin (doo TAS ter ide and tam soo LOE sin)
Brand name: Jalyn
Drug class: 5-alpha-reductase inhibitors, Antiadrenergic agents, peripherally acting

Medically reviewed by Philip Thornton, DipPharm. Last updated on Jul 9, 2021.

What is Jalyn?

Jalyn contains a combination of dutasteride and tamsulosin. Dutasteride prevents testosterone from converting to dihydrotestosterone (DHT) in the body. DHT is involved in the development of benign prostatic hyperplasia (BPH).

Tamsulosin relaxes the muscles in the prostate and bladder neck, making it easier to urinate.

Jalyn is used to treat benign prostatic hyperplasia (BPH) in men with an enlarged prostate.

Warnings

Jalyn should never be handled or taken by a woman, a child, or a teenager. Dutasteride can be absorbed through the skin. This medication can cause birth defects if a woman is exposed to it during pregnancy. The capsules should not be handled by a woman who is pregnant or who may become pregnant. If a woman accidentally comes into contact with the medication from a leaking capsule, wash the area with soap and water right away. Do not donate blood while taking Jalyn and for at least 6 months after your treatment ends. Dutasteride can be carried in the blood and could cause birth defects if a pregnant women receives a transfusion with blood that contains dutasteride.

You should not use Jalyn if you are allergic to dutasteride (Avodart) or tamsulosin (Flomax). Do not take this medicine if you are also taking alfuzosin (Uroxatral), doxazosin (Cardura), prazosin (Minipress), silodosin (Rapaflo), tamsulosin (Flomax), or terazosin (Hytrin).

There are many other drugs that can interact with dutasteride and tamsulosin. Tell your doctor about all medications you use.

Jalyn should never be taken by a woman, a child, or a teenager.

Jalyn may increase your risk of developing prostate cancer. Your doctor will perform tests to make sure you do not have other conditions that would prevent you from safely using this medicine.

Tamsulosin can affect your pupils during cataract surgery. Tell your eye surgeon ahead of time that you are using this medication. Do not stop using Jalyn before surgery unless your surgeon tells you to.

Before taking this medicine

You should not use Jalyn if you are allergic to dutasteride, finasteride, or tamsulosin.

You should not take this medicine while you are taking tamsulosin (Flomax) or similar medicines, such as alfuzosin, doxazosin, prazosin, silodosin, or terazosin.

Jalyn should never be taken by a woman, a child, or a teenager. Dutasteride can be absorbed through the skin, and women or children should not be permitted to handle Jalyn capsules.

This medicine is not for use by women. This medicine can cause birth defects. The capsules should not be handled by a woman who is pregnant or who may become pregnant.

If a woman accidentally comes into contact with this medication from a leaking capsule, wash the area with soap and water right away.

To make sure Jalyn is safe for you, tell your doctor if you have ever had:

Using this medicine may increase your risk of developing prostate cancer. Ask your doctor about this risk.

Jalyn can affect your pupils. If you need eye surgery, tell the surgeon about your use of this medicine, even if you no longer take it.

How should I take Jalyn?

Take Jalyn exactly as prescribed by your doctor. Follow all directions on your prescription label and read all medication guides or instruction sheets.

Take this medicine 30 minutes after a meal, at the same time each day.

Swallow the Jalyn capsule whole and do not crush, chew, break, or open it.

You will need medical tests to check your prostate specific antigen (PSA).

Store at room temperature away from moisture and heat.

Dosing information

Usual Adult Dose for Benign Prostatic Hyperplasia:

Dutasteride 0.5 mg-Tamsulosin 0.4 mg orally once a day approximately 30 minutes after the same meal each day

Use: Treatment of symptomatic benign prostatic hyperplasia (BPH) in men with an enlarged prostate.

What happens if I miss a dose?

Take your dose as soon as you can, but only within 30 minutes after a meal. Skip the missed dose if it is almost time for your next dose. Do not take two doses at one time.

Call your doctor if you miss your doses for several days in a row.

What happens if I overdose?

Seek emergency medical attention or call the Poison Help line at 1-800-222-1222.

What should I avoid while taking Jalyn?

Avoid taking medicines for erectile dysfunction (sildenafil, avanafil, Viagra, Cialis, and others).

Do not donate blood while taking this medicine and for at least 6 months after your last dose. Dutasteride could cause birth defects if a pregnant women receives a transfusion with blood that contains this medicine.

Avoid getting up too fast from a sitting or lying position, or you may feel dizzy.

Avoid driving or hazardous activity until you know how this medicine will affect you. Your reactions could be impaired.

Jalyn side effects

Get emergency medical help if you have signs of an allergic reaction to Jalyn (hives, difficult breathing, swelling in your face or throat) or a severe skin reaction (fever, sore throat, burning eyes, skin pain, red or purple skin rash with blistering and peeling).

Stop using this medicine and call your doctor at once if you have:

  • a light-headed feeling, like you might pass out; or

  • penis erection that is painful or lasts 4 hours or longer.

Common Jalyn side effects may include:

  • decreased libido (sex drive);

  • decreased amount of semen released during sex;

  • impotence (trouble getting or keeping an erection);

  • breast tenderness or enlargement;

  • dizziness; or

  • runny nose.

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

What other drugs will affect Jalyn?

Sometimes it is not safe to use certain medications at the same time. Some drugs can affect your blood levels of other drugs you take, which may increase side effects or make the medications less effective.

Other drugs may interact with dutasteride and tamsulosin, including prescription and over-the-counter medicines, vitamins, and herbal products. Tell your doctor about all other medicines you use.

Further information

Remember, keep this and all other medicines out of the reach of children, never share your medicines with others, and use Jalyn only for the indication prescribed.

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.