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Herbal Supplements and Alcohol Interactions

Medically reviewed by L. Anderson, PharmD Last updated on Nov 7, 2017.

Not all herbal products or dietary supplements interact with alcohol, but reliable studies are often not available. You may be at risk for additive drowsiness, liver damage, impaired breathing, or other side effects, depending upon the dietary supplement.

Learn More: 18 Herbal Supplements with Risky Drug Interactions

Use caution if combining any over-the-counter or dietary supplement that causes drowsiness with alcohol. Review the label on the bottle and speak with your pharmacist or doctor if you plan on taking an herbal dietary supplement and drinking alcohol. Do not drive until you are aware of the effects of the supplement.

These herbal drugs have been known to lead to drowsiness in some patients, which may be increased when combined with alcohol:

  • 5-HTP (5-hydroxytryptophan)
  • California poppy
  • Catnip
  • Gotu kola
  • Jamaican dogwood
  • Kava
  • Melatonin
  • St. John's wort
  • Skullcap
  • Valerian
  • Yerba mansa

Types of Drug Interactions With Alcohol

Further information

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.