How does Zinbryta work?
Zinbryta (daclizumab) is an interleukin-2 receptor blocking antibody for the treatment of adults with relapsing forms of multiple sclerosis (MS). It is thought to work by decreasing T-cells and pro-inflammatory lymphoid tissue inducer cells, and increasing CD56bright natural killer (NK) cells, important cells that help regulate the immune system.
Zinbryta should only be used in patients who have had an inadequate response to two or more multiple sclerosis drugs.
The Zinbryta product label carries a boxed warning advising the serious safety risks, including liver injury and immune disorders.
Zinbryta is available only through a restricted distribution program under a Risk Evaluation and Mitigation Strategy.
Read next
How long can you live with multiple sclerosis?
Multiple sclerosis (MS) is not generally considered life-threatening and most people will live a normal life-span. One study has found that the average life expectancy for people with MS is 76 years of age. In 2019, the U.S. life-expectancy averaged 78.8 years, but in 2020 it declined to 77.3 years, primarily due to the COVID pandemic. Many people with MS may live for 25 to 35 years or longer after their diagnosis. Continue reading
What are the early signs of multiple sclerosis?
Some of the early signs of multiple sclerosis (MS) include weakness or numbness in one or more limbs; tremor or abnormal, uncoordinated movements while walking; slurred speech, or dizziness; double vision or the painful loss of vision in one eye; or long-lasting fatigue. Continue reading
What's a good prednisone taper schedule?
The best prednisone taper will depend upon how long you have been taking the medicine, your dose, and why you are being treated. If you've been treated with a high dose of prednisone, or taken it for more than a few weeks, you will need to slowly stop your medicine, usually over a period of days, weeks or months. Your healthcare provider will determine your prednisone tapering schedule. Continue reading
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Drug information
- Zinbryta Information for Consumers
- Zinbryta prescribing info & package insert (for Health Professionals)
- Side Effects of Zinbryta (detailed)
Related support groups
- Zinbryta (1 questions, 3 members)
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