Zinbryta Side Effects

Generic name: daclizumab

Medically reviewed by Drugs.com. Last updated on Apr 6, 2025.

Note: This document provides detailed information about Zinbryta Side Effects associated with daclizumab. Some dosage forms listed on this page may not apply specifically to the brand name Zinbryta.

Applies to daclizumab: intravenous solution.

Precautions

If you are continuing your course of therapy with daclizumab (the active ingredient contained in Zinbryta) after you are discharged from the hospital, it is very important that your doctor check your progress at regular visits. Your doctor will want to do laboratory tests to make sure daclizumab is working properly.

This medicine may cause a serious type of allergic reaction called anaphylaxis. Anaphylaxis can be life-threatening and requires immediate medical attention. Tell your doctor or nurse right away if you have a skin rash; itching; swelling of the face, tongue, and throat; or trouble with breathing after you get the injection.

You may be more likely to get infections while using this medicine. Tell your doctor if you have symptoms of an infection, such as fever or chills. Try to stay away from people with colds, flu, or other infections.

Using this medicine may cause you to have a higher risk of getting cancer of the lymph system. Talk to your doctor if you have concerns about this risk.

Dental—It is important to maintain good dental hygiene and see a dentist regularly for teeth cleaning.

If you are a woman of childbearing age, you should use effective contraception while receiving this medicine.

Serious side effects of Zinbryta

Along with its needed effects, daclizumab may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.

Check with your doctor or nurse immediately if any of the following side effects occur while taking daclizumab:

Other side effects of Zinbryta

Some side effects of daclizumab may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects.

Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:

For healthcare professionals

Applies to daclizumab: intravenous solution, subcutaneous solution.

Cardiovascular adverse events

• Common (1% to 10%): Lymphadenopathy, lymphadenitis^[Ref]

Dermatologic

• Very common (10% or more): Rash (i.e., erythematous rash, exfoliative rash, macular rash, maculopapular rash, papular rash, pruritic rash, rash, vesicular rash) (11%)
• Common (1% to 10%): Dermatitis (i.e., allergic dermatitis, atopic dermatitis, bullous dermatitis, dermatitis, exfoliative dermatitis, seborrheic dermatitis, eczema, allergic dermatitis), folliculitis, acne, psoriasis, erythema, pruritus, dry skin
• Uncommon (0.1% to 1%): Toxic skin eruption, eczema nummular^[Ref]

Gastrointestinal

• Common (1% to 10%): Tonsillitis, diarrhea
• Frequency not reported: Colitis^[Ref]

Hematologic

• Common (1% to 10%): Anemia, lymphocyte count decreased^[Ref]

Hypersensitivity

• Frequency not reported: Anaphylaxis^[Ref]

Respiratory

• Very common (10% or more): Nasopharyngitis (25%), upper respiratory tract infection (17%)
• Common (1% to 10%): Bronchitis, pneumonia, laryngitis, rhinitis^[Ref]

Psychiatric

• Common (1% to 10%): Depression^[Ref]

Other

• Common (1% to 10%): Oropharyngeal pain, pyrexia^[Ref]

Hepatic

• Common (1% to 10%): ALT increased, AST increased, liver function test abnormal, hepatic enzymes increased^[Ref]

Immunologic

• Common (1% to 10%): Influenza, viral infection^[Ref]

See also:

Frequently asked questions

• What are the new drugs used for multiple sclerosis (MS)?
• How does Zinbryta work?

Further information

Zinbryta side effects can vary depending on the individual. Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.

Note: Medication side effects may be underreported. If you are experiencing side effects that are not listed, submit a report to the FDA by following this guide.

Medical Disclaimer