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Nabumetone Patient Tips

Medically reviewed by Carmen Pope, BPharm. Last updated on Sep 10, 2025.

1. How it works

2. Upsides

3. Downsides

If you are between the ages of 18 and 60, take no other medication or have no other medical conditions, side effects you are more likely to experience include:

Note: In general, seniors or children, people with certain medical conditions (such as liver or kidney problems, heart disease, diabetes, seizures) or people who take other medications are more at risk of developing a wider range of side effects. View complete list of side effects

4. Bottom Line

Nabumetone treats pain and inflammation from osteoarthritis and rheumatoid arthritis in adults. Can be taken once daily and causes fewer stomach problems than other NSAIDs. Common side effects include diarrhea, stomach pain, nausea, constipation. Avoid after 20 weeks pregnancy due to fetal kidney problems and ductus arteriosus closure risks.

5. Tips

6. Response and effectiveness

7. Interactions

Medicines that interact with nabumetone may either decrease its effect, affect how long it works, increase side effects, or have less of an effect when taken with nabumetone. An interaction between two medications does not always mean that you must stop taking one of the medications; however, sometimes it does. Speak to your doctor about how drug interactions should be managed.

Common medications that may interact with nabumetone include:

Drinking alcohol while taking nabumetone may increase the risk of gastrointestinal-related side effects or kidney damage.

Note that this list is not all-inclusive and includes only common medications that may interact with nabumetone. You should refer to the prescribing information for nabumetone for a complete list of interactions.

Related/similar drugs

References

Further information

Remember, keep this and all other medicines out of the reach of children, never share your medicines with others, and use nabumetone only for the indication prescribed.

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.

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