Lipitor Patient Tips
How it works
- Lipitor is a brand (trade) name for atorvastatin. Atorvastatin may be is used for the treatment of high cholesterol.
- Atorvastatin works by blocking an enzyme in the liver that makes different types of lipids (fats and cholesterol). Atorvastatin also boosts the breakdown of lipids.
- Lipitor belongs to the class of medicines known as statins. Lipitor is also known as an HMG-CoA reductase inhibitor.
- Lipitor, in conjunction with dietary measures, may be used for the treatment of high cholesterol in people at increased risk of cardiovascular disease if initial dietary measures fail to lower cholesterol.
- Lipitor is also used to lower the risk of coronary events (includes heart attack, stroke, and angina) in patients at high risk of these events - such as people with pre-existing coronary heart disease, diabetes, peripheral vessel disease, a previous history of stroke and stroke-like events or heart attack, or with multiple risk factors (such as older age, smoking, high blood pressure, low HDL-C, and a family history of heart disease).
- Possibly more effective than other statins.
- Lipitor is available as a generic under the name atorvastatin.
If you are between the ages of 18 and 60, take no other medication or have no other medical conditions, side effects you are more likely to experience include:
- Nasopharyngitis (swelling of the nasal passages and back of the throat), arthralgia (joint pain), diarrhea, dyspepsia, pain, and urinary tract infections.
- Muscle pain, tenderness, or weakness - initially needs further investigation to rule out more serious muscle effects (such as rhabdomyolysis - the destruction of muscle cells). People aged older than 65, taking certain medications (for example cyclosporine, itraconazole, HIV antivirals), who drink more than two alcoholic drinks per day or with kidney disease appear more at risk of serious side effects.
- Lipitor, like other statins, may affect liver function, manifesting as changes in liver function tests or jaundice (yellowing of the skin) requiring dosage reduction or discontinuation.
- May also affect some diabetes markers (such as HbA1c or fasting glucose), and may not be suitable in those with liver or kidney disease.
- Rarely, has been associated with memory loss, forgetfulness, amnesia, memory impairment, and confusion. These symptoms typically resolve with discontinuation.
- May interact with a number of other medications including those metabolized by hepatic enzymes CYP 3A4, clarithromycin, protease inhibitors, cyclosporine, gemfibrozil, oral contraceptives, and digoxin.
Notes: In general, seniors or children, people with certain medical conditions (such as liver or kidney problems, heart disease, diabetes, seizures) or people who take other medications are more at risk of developing a wider range of side effects. For a complete list of all side effects, click here.
- Take once daily. May be taken at any time of the day (morning or night); however, it is best to be consistent with the time you take Lipitor.
- The dosage of Lipitor needs to be individualized but initially should start at 10-20 mg/day and be guided by the results of cholesterol tests taken 2 to 4 weeks later.
- Take Lipitor exactly as directed by your doctor. Do not increase or decrease the dosage without his or her advice.
- Avoid drinking large quantities of grapefruit juice or eating grapefruit or grapefruit products while taking atorvastatin.
- Limit your alcohol intake and avoid drinking more than two glasses of alcohol per day while you are taking Lipitor.
- Consider temporarily withholding Lipitor and seeking urgent medical advice if you have any acute muscle pain or another condition that may increase your risk of serious muscle injury or kidney failure such as a severe infection, major surgery, trauma, uncontrolled seizures, severe electrolyte or metabolic disorders.
- Adhere to the TLC diet, designed by the National Cholesterol Education Program (NCEP), or a similar diet, while taking Lipitor.
- Plan to exercise regularly and stop smoking if you smoke. Try to avoid second-hand smoke.
- See your doctor straight away if you notice any yellowing of your skin or shortness of breath, unexplained cough or general tiredness.
- Lipitor should not be taken during pregnancy or while breastfeeding. Ensure you use effective contraception while taking Lipitor if you are a woman of childbearing age and talk to your doctor if you intend to become pregnant before you actually become pregnant.
Response and Effectiveness
- Peak levels are seen within one to two hours following administration; however, it may take one to two weeks of regular dosing before improvements in your cholesterol level are seen, and up to four weeks before the maximal cholesterol-lowering effects of Lipitor are apparent.
- May lower total cholesterol by 30-46%, triglycerides by 30-56%, with variable increases seen in HDL.
- Possibly more effective than other statins.
Lipitor (atorvastatin) [Package Insert] Revised: 07/2017. Parke-Davis Div of Pfizer Inc. https://www.drugs.com/pro/lipitor.html
More about Lipitor (atorvastatin)
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- Generic Availability
- Drug class: statins
Related treatment guides
- Remember, keep this and all other medicines out of the reach of children, never share your medicines with others, and use Lipitor only for the indication prescribed.
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