Does Lipitor work better if you take it at night?
Medically reviewed by Drugs.com. Last updated on Nov 3, 2020.
Lipitor can be taken at anytime. If a statin has a half life of less than 6 hours it should be taken at night. The half life of Lipitor is 14 hours and its active metabolites up to 20 to 30 hours therefore Lipitor can be taken at anytime.
Lipitor belongs to a group of prescription medicines called statins. Statins are used to lower cholesterol. They inhibit an enzyme that your body needs to produce cholesterol and targets low-density lipoprotein (LDL) cholesterol (bad cholesterol).
The elimination half-life of statins, or the amount of time it takes for half the dose to leave your body, determines if the drug should be taken in the evening when the cholesterol-making enzyme is more active, or if it can be taken anytime.
If a statin has a half life of less than 6 hours it should be taken at night. The half life of Lipitor is 14 hours and its active metabolites up to 20 to 30 hours therefore Lipitor can be taken at anytime.
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