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Flonase: Avoid These Top 9 Mistakes

Medically reviewed by Leigh Ann Anderson, PharmD. Last updated on Aug 16, 2021.

I'll Just Use Flonase Allergy When My Allergies Flare Up

It may take 3 to 4 days of regular use of Flonase Allergy or Flonase Sensimist to feel the full effect during allergy season. For this reason, nasal steroids like fluticasone are most effective when used on a regular basis.

Used for relief of all nasal and eye-related allergy symptoms, including runny nose, sneezing, itchy nose, nasal congestion, and itchy and watery eyes. Used for seasonal and year-round allergies, including pollen, mold, dust, and pet dander.

Flonase (fluticasone propionate) Allergy Relief

  • Adults and children 12 years and older - Use 2 sprays (50 mcg/spray) in each nostril once per day for the first week. After the first week you may adjust your dose to 1 to 2 sprays per nostril every day as need to control your symptoms. After 6 months of daily use, check with your doctor for continued use.
  • Children 4 to 11 years - With adult supervision, use 1 spray (50 mcg/spray) in each nostril once daily. Talk to your child’s doctor if your child needs to use the spray for longer than 2 months a year.
  • Do not use this product in children under 4 years of age.

Flonase Sensimist (fluticasone furoate) Allergy Relief

  • Flonase Sensimist delivers a fine mist that is alcohol and scent-free.
  • Adults and children 12 years and older: Give as 2 sprays (27.5 mcg/spray) in each nostril once daily for the first week. After one week, you may adjust your dose to 1 to 2 sprays in each nostril once daily, as needed to treat symptoms. In those 12 years of age and older, check with your doctor for continued use after 6 months of daily use.
  • Children 2 to 11 years: With adult supervision, give as 1 spray (27.5 mcg/spray) in each nostril once daily. Do not increase this dose, and use the shortest amount of time needed to control symptoms. Check with your child’s doctor if your child needs to use the spray for longer than 2 months a year. Do not use in children under 2 years of age.

Refer to the Over-the-Counter (OTC) Drug Facts Labeling for specific information.

I'll Give My Child the Same Dose That I Use

Wrong. Kids are not just small adults. There is now a formulation for kids 4 years and older called Children's Flonase Allergy Relief.

  • It comes in the same strength as the adult formulation (50 mcg per spray) but in a smaller size (72 sprays instead of 144) -- so it's less expensive, too.
  • The dose for children 4 years and older, under adult supervision, is 1 spray in each nostril once daily.
  • If you have the larger bottle of Flonase Allergy Relief, you can use it, just be sure to only give the child's dose.

The growth rate of some children may be slowed, so they should use Flonase Allergy for the shortest amount of time possible to control symptoms. If your child needs Flonase Allergy for longer than two months per year, talk to your child's doctor for advice.

If your child is 2 to 11 years, they can use Flonase Sensimist Allergy Relief instead. The dose is 1 spray (27.5 mcg/spray) in each nostril once a day. It is a scent-free and alcohol-free formulation that may be easier on tiny noses. The bottle holds 60 or 120 sprays.

I'll Need to Buy Allergy Eye Drops

Most likely not. Flonase can handle your itchy, red, watery eyes in addition to your runny nose.

Allergic rhinitis symptoms that can be reduced include:

  • sneezing
  • nasal congestion (stuffy nose)
  • runny nose
  • itchy nose and eyes
  • watery eyes.

However, the Flonase Sensimist Allergy Relief product is used for itchy, watery eyes only for individuals 12 years of age and older. It has not been studied for this use in younger patients.

Most antihistamines only block histamine, but Flonase blocks histamine, plus 5 other allergy-worsening substances in your body, like cytokines and leukotrienes. If you need to continue the medicine year-round, just be sure to check with doctor.

Prescription Flonase is Stronger So I'll Use It Instead


Over-the-counter Flonase Allergy Relief is exactly the same as prescription Flonase -- it’s the same medicine, fluticasone propionate, at the same strength and dose. The brand product Flonase is now discontinued, but generics and store brands are available.

OTC Flonase Sensimist Allergy Relief (fluticasone furoate) is the same strength and medicine as prescription Veramyst, which is now also discontinued.

  • With OTC approvals, the amount of money you pay for your medicine may differ from a prescription product.
  • Since Flonase is now available over-the-counter (OTC), insurance plans may not pay for the prescription brand name product, and your costs could be significantly higher than the OTC Flonase. However, if you have a health savings account (HSA), you can probably use funds from that to pay for OTC medicines. This changed in 2020 with the CARES Act.
  • Your insurance might pay for the prescription generic fluticasone propionate (Flonase), but you may need a visit to the doc and a prescription. You might be able to pay even less for the generic prescription product than the OTC, ask your pharmacist about this.

Also, ask your pharmacist to do a cost comparison for you. Online coupons or a discount card may be helpful, too, for prescription products.

Since Flonase Allergy is a Nasal Spray, I Don't Have to Be Worried About Drug Interactions

  • There is the possibility of some significant interactions between Flonase Allergy and other common medications. Some drug interactions might raise the levels of fluticasone in your body and lead to side effects.
  • Some interactions can occur when fluticasone is given with medicines that inhibit an enzyme in the body known CYP450 3A4. This may increase the amount of fluticasone in your body following intranasal administration.

You should talk to your pharmacist or doctor about the possibility of drug interactions before using any drugs with Flonase Allergy, including:

  • Certain HIV medications, including ritonavir, boceprevir, and atazanavir
  • Clarithromycin (Biaxin)
  • Certain azole antifungals like ketoconazole used for fungal infections
  • Even an herbal product called Echinacea

Learn more: Fluticasone nasal drug interactions (in detail)

It is important to tell your doctor and pharmacist about all the medications you use, including prescription, over-the-counter, dietary supplements, vitamins and herbs. Do not stop using any medications without first talking to your doctor.

I'll Keep Taking My Antihistamine Pill For Added Effect

You usually don't need to keep taking an oral allergy pill if you are using Flonase Allergy at the right dose. But always follow your doctor's directions.

  • Intranasal glucocorticoids are very effective as a single treatment and cause few side effects at the recommended doses.
  • Nose bleeds and coughing are the most common side effects.
  • Intranasal steroids usually work better than oral antihistamines (such as Claritin, Zyrtec, Allegra) for nasal congestion, sneezing and post-nasal drip because they address many of the inflammatory molecules in the body that lead to allergies, not just histamine.
  • Plus, antihistamines like Benadryl and Zyrtec may cause drowsiness and make driving a hazard or classroom learning a challenge.

Learn More: Allergy Guide: Prevention and Treatment Options

Flonase Allergy is OTC So I Can't Use My Flex Account

Flonase Allergy Relief averages about $20 to $25 per bottle for 144 spray size, and about $15 for the 72 spray size at most pharmacies and retail shops. You can sign up for a coupon on the manufacturer's website, too. The cost for and Flonase Sensimist is roughly the same.

You may be able to purchase Flonase over-the-counter products using your healthcare flexible spending account (FSA or HSA card).

  • In 2020, the CARES Act expanded the coverage of OTC products for these accounts.
  • The rules are dependent upon your flex plan, too, so check with your insurance carrier or employer about using your flex account for over-the-counter medications written on a prescription by your doctor.

I'll Need to Keep Fido Outside

No need to keep your best friend out in the backyard. A benefit of fluticasone nasal is that it works for both indoor and outdoor allergy triggers.

Indoor allergens include: cat and dog dander, dust mites, cockroach droppings, mold and pollen tracked in from the outside.

Outdoor allergens are familiar culprits like: pollen from ragweed, grass, and trees and outdoor mold spores.

So go ahead, keep your four-legged friend close-by in all seasons and year-round.

Aren't Prescription Medicines Better for Allergies?

This couldn't be further from the truth. Allergy medicines are one of the top prescription to over-the-counter (Rx-to-OTC) switches made in the US.

Just think of the previous prescription antihistamines that are now available over-the-counter at the pharmacy without a prescription: Claritin, Zyrtec, Xyzal and Allegra.

Plus, in addition to Flonase Allergy and Flonase Sensimist, there is now over-the-counter Nasacort (triamcinolone) Allergy 24HR Spray and Rhinocort Allergy Nasal Spray (budesonide). In June 2021, Astepro Allergy, a steroid-free antihistamine nasal spray, also went from prescription to OTC status.

But how do you keep up with all the changes and products?

Finished: Flonase: Avoid These Top 9 Mistakes

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  • Flonase. GSK Consumer Healthcare. Product Labeling. 2021. Accessed August 16, 2021 at
  • Flonase Sensimist. Accessed August 16, 2021 at
  • Flonase Allergy Relief. Accessed August 16, 2021

Further information

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.