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Vitelle Nestrex Side Effects

Generic Name: pyridoxine

Note: This document contains side effect information about pyridoxine. Some of the dosage forms listed on this page may not apply to the brand name Vitelle Nestrex.

For the Consumer

Applies to pyridoxine: capsule, injectable, solution, tablet, tablet enteric coated, tablet extended release

Along with its needed effects, pyridoxine (the active ingredient contained in Vitelle Nestrex) may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.

Check with your doctor as soon as possible if any of the following side effects occur while taking pyridoxine:

With large doses

For Healthcare Professionals

Applies to pyridoxine: compounding powder, injectable solution, oral capsule, oral tablet

Nervous system

The profound sensory loss following treatment with high doses of parenteral pyridoxine (the active ingredient contained in Vitelle Nestrex) may not be reversible.[Ref]

Nervous system side effects have included sensory neuropathy with axonal degeneration. The adverse neurologic side effects have been reported following a single large dose (10 g) administered intravenously. It may rarely occur following chronic administration of lower doses. Peripheral sensory neuropathy has also been reported.[Ref]


Hypersensitivity side effects have been reported rarely.[Ref]


Dermatologic side effects have included allergic contact dermatitis. Photosensitivity has been confirmed in a female patient taking pyridoxine (the active ingredient contained in Vitelle Nestrex) 100 mg orally daily.[Ref]


1. Albin RL, Albers JW "Long-term follow-up of pyridoxine-induced acute sensory neuropathy- neuronopathy." Neurology 40 (1990): 1319

2. "Multum Information Services, Inc. Expert Review Panel"

3. Morimoto K, Kawada A, Hiruma M, Ishibashi A "Photosensitivity from pyridoxine hydrochloride (vitamin b-6)." J Am Acad Dermatol 35 (1996): 304-5

4. Camarasa JG, Serra-Baldrich E, Lluch M "Contact allergy to vitamin B6." Contact Dermatitis 23 (1990): 115

Some side effects of Vitelle Nestrex may not be reported. Always consult your doctor or healthcare specialist for medical advice. You may also report side effects to the FDA.

Disclaimer: Every effort has been made to ensure that the information provided is accurate, up-to-date and complete, but no guarantee is made to that effect. In addition, the drug information contained herein may be time sensitive and should not be utilized as a reference resource beyond the date hereof. This material does not endorse drugs, diagnose patients, or recommend therapy. This information is a reference resource designed as supplement to, and not a substitute for, the expertise, skill , knowledge, and judgement of healthcare practitioners in patient care. The absence of a warning for a given drug or combination thereof in no way should be construed to indicate safety, effectiveness, or appropriateness for any given patient. does not assume any responsibility for any aspect of healthcare administered with the aid of materials provided. The information contained herein is not intended to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions, or adverse effects. If you have questions about the substances you are taking, check with your doctor, nurse, or pharmacist.