Utibron Neohaler Side Effects

Generic name: glycopyrrolate / indacaterol

Medically reviewed by Drugs.com. Last updated on Feb 4, 2025.

Note: This document provides detailed information about Utibron Neohaler.

Applies to glycopyrrolate / indacaterol: inhalation capsule Side Effects associated with glycopyrrolate / indacaterol. Some dosage forms listed on this page may not apply specifically to the brand name Utibron Neohaler.

Applies to glycopyrrolate / indacaterol: inhalation capsule.

Precautions

It is very important that your doctor check your progress at regular visits to make sure the medicine is working properly. Blood and urine tests may be needed to check for any unwanted effects.

Tell your doctor if you are also using any other medicine for your COPD. Your doctor may want you to use it only during a severe COPD attack. Follow your doctor's instructions on how you should take your medicine.

This medicine should not be used if you are having a severe COPD attack, or if symptoms of COPD attack has already started. Your doctor may prescribe another medicine for you to use in case of an acute COPD attack. If the other medicine does not work as well, tell your doctor right away.

Talk to your doctor or get medical care right away if:

• Your symptoms do not improve after using this medicine for a few days or if they become worse.
• Your short-acting inhaler does not seem to be working as well as usual and you need to use it more often.

Do not use this medicine together with other inhaled medicines for COPD, including arformoterol (Brovana™), budesonide/formoterol (Symbicort®), formoterol (Foradil®, Perforomist®), indacaterol (Arcapta® Neohaler®), salmeterol (Serevent®), salmeterol/fluticasone (Advair®), or vilanterol.

This medicine may increase the risk of worsening asthma, which may lead to hospitalization, intubation, and death in patients with asthma who take this medicine without an inhaled steroid medicine. Talk to your doctor if you have concerns about this.

This medicine may cause paradoxical bronchospasm, which means your breathing or wheezing will get worse. This may be a life-threatening situation. Check with your doctor right away if you have a cough, difficulty with breathing, shortness of breath, or wheezing after using this medicine.

This medicine may cause serious allergic reactions, including angioedema, which can be life-threatening and require immediate medical attention. Tell your doctor right away if you have a rash, itching, hoarseness, trouble breathing, trouble swallowing, or any swelling of your hands, face, or mouth after using this medicine.

This medicine may cause heart or blood vessel problems, including heart rhythm problems. Check with your doctor right away if you have chest pain or tightness, decreased urine output, dilated neck veins, extreme fatigue, irregular heartbeat, swelling of the face, fingers, feet, or lower legs, troubled breathing, or weight gain.

Call your doctor right away if blurred vision, difficulty in reading, seeing halos around lights, or any other change in vision occurs during or after treatment. Your doctor may want your eyes be checked by an ophthalmologist (eye doctor).

Check with your doctor right away if you have a decrease in urine volume, decrease in the frequency of urination, difficulty in passing urine, or painful urination.

Hypokalemia (low potassium in the blood) may occur while you are using this medicine. Check with your doctor right away if you have more than one of the following symptoms: decreased urine, dry mouth, increased thirst, loss of appetite, mood changes, muscle pain or cramps, nausea or vomiting, numbness or tingling in the hands, feet, or lips, seizures, uneven heartbeat, or unusual tiredness or weakness.

This medicine may affect blood sugar levels. If you are diabetic and notice a change in the results of your blood or urine sugar tests, check with your doctor.

Do not take other medicines unless they have been discussed with your doctor. This includes prescription or nonprescription (over-the-counter [OTC]) medicines and herbal or vitamin supplements.

Serious side effects of Utibron Neohaler

Along with its needed effects, glycopyrrolate/indacaterol may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.

Check with your doctor immediately if any of the following side effects occur while taking glycopyrrolate / indacaterol:

Other side effects of Utibron Neohaler

Some side effects of glycopyrrolate / indacaterol may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects.

Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:

For healthcare professionals

Applies to glycopyrrolate / indacaterol: inhalation capsule.

General adverse events

The most common adverse reaction was nasopharyngitis and hypertension. Cough was also common, but usually of mild intensity.^[Ref]

Respiratory

• Very common (10% or more): Upper and lower respiratory tract infection
• Common (1% to 10%): Nasopharyngitis (4.1%), oropharyngeal pain (1.6%), pneumonia, rhinitis, sinusitis, cough, throat irritation
• Uncommon (0.1% to 1%): Paradoxical bronchospasm, epistaxis
• Very rare (less than 0.01%): Chest pain^[Ref]

Gastrointestinal

• Common (1% to 10%): Diarrhea, gastroesophageal reflux disease, dyspepsia, dental caries, gastroenteritis
• Uncommon (0.1% to 1%): Dry mouth^[Ref]

Metabolic

• Common (1% to 10%): Hyperglycemia
• Uncommon (0.1% to 1%): Diabetes mellitus^[Ref]

Musculoskeletal

• Common (1% to 10%): Back pain, musculoskeletal pain
• Uncommon (0.1% to 1%): Muscle spasm, myalgia, pain in extremity^[Ref]

Nervous system

• Common (1% to 10%): Dizziness, headache
• Uncommon (0.1% to 1%): Paraesthesia^[Ref]

Other

• Common (1% to 10%): Pyrexia
• Uncommon (0.1% to 1%): Fatigue, peripheral edema^[Ref]

Cardiovascular

• Uncommon (0.1% to 1%): Hypertension (2%), ischemic heart disease, atrial fibrillation, tachycardia, palpitations
• Very rare (less than 0.01%): Atrial fibrillation, palpitations, tachycardia^[Ref]

Dermatologic

• Uncommon (0.1% to 1%): Angioedema, rash, pruritus^[Ref]

Genitourinary

• Uncommon (0.1% to 1%): Bladder obstruction, urinary retention^[Ref]

Ocular

• Uncommon (0.1% to 1%): Glaucoma^[Ref]

Psychiatric

• Uncommon (0.1% to 1%): Insomnia^[Ref]

See also:

Frequently asked questions

• How do you use a Utibron Neohaler?

Further information

Utibron Neohaler side effects can vary depending on the individual. Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.

Note: Medication side effects may be underreported. If you are experiencing side effects that are not listed, submit a report to the FDA by following this guide.

Medical Disclaimer