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Tussigon Side Effects

Generic Name: homatropine / hydrocodone

Note: This page contains side effects data for the generic drug homatropine / hydrocodone. It is possible that some of the dosage forms included below may not apply to the brand name Tussigon.

For the Consumer

Applies to homatropine / hydrocodone: oral solution, oral syrup, oral tablet

As well as its needed effects, homatropine / hydrocodone may cause unwanted side effects that require medical attention.

Major Side Effects

If any of the following side effects occur while taking homatropine / hydrocodone, check with your doctor immediately:

Incidence not known:
  • Decrease in the frequency of urination
  • decrease in urine volume
  • difficulty in passing urine (dribbling)
  • painful urination

If any of the following symptoms of overdose occur while taking homatropine / hydrocodone, get emergency help immediately:

Symptoms of overdose:
  • Difficult or troubled breathing
  • irregular, fast or slow, or shallow breathing
  • pale or blue lips, fingernails, or skin

Minor Side Effects

Some homatropine / hydrocodone side effects may not need any medical attention. As your body gets used to the medicine these side effects may disappear. Your health care professional may be able to help you prevent or reduce these side effects, but do check with them if any of the following side effects continue, or if you are concerned about them:

More common:
  • Nausea
  • vomiting
Incidence not known:
  • Drowsiness
  • fear or nervousness
  • itching skin or rash
  • mood changes
  • relaxed and calm
  • sleepiness
  • unusual drowsiness, dullness, tiredness, weakness, or feeling of sluggishness

For Healthcare Professionals

Applies to homatropine / hydrocodone: oral syrup, oral tablet

Nervous system

One study has suggested that the respiratory depression caused by hydrocodone may be of benefit in the treatment of dyspnea related to chronic obstructive pulmonary disease and restrictive lung disease. However, the potential for the precipitation of respiratory insufficiency makes such use of hydrocodone hazardous and such use should be undertaken, if at all, only with extreme caution.[Ref]

Nervous system side effects of hydrocodone have included mental depression, drowsiness, dizziness, lightheadedness, respiratory depression (which is sometimes fatal), stupor, delirium, somnolence, agitation, and dysphoria.[Ref]

Other

Other side effects of hydrocodone have included withdrawal symptoms, such as agitation, restlessness, anxiety, insomnia, tremor, abdominal cramps, blurred vision, vomiting and sweating, after either abrupt cessation or fast tapering of narcotic analgesics.[Ref]

Gastrointestinal

Gastrointestinal side effects of hydrocodone have included nausea, vomiting, constipation, and dry mouth.[Ref]

Genitourinary

Genitourinary side effects of hydrocodone have included ureteral spasm, spasm of vesicle sphincters, and urinary retention.[Ref]

Dermatologic

Dermatologic side effects of hydrocodone have included rash.[Ref]

References

1. Sackner MA "Effects of hydrocodone bitartrate on breathing pattern of patients with chronic obstructive pulmonary disease and restrictive lung disease." Mt Sinai J Med 51 (1984): 222-6

2. "Product Information. Hycodan (homatropine-hydrocodone)" Endo Laboratories LLC, Chadds Ford, PA.

3. Fricke J, Halladay SC, Bynum L, Francisco CA "Pain relief after dental impaction surgery using ketorolac, hydrocodone plus acetaminophen, or placebo." Clin Ther 15 (1993): 500-9

4. Morrison AB "Toxicity and abuse of hydrocodone bitartrate." Can Med Assoc J 120 (1979): 1338

It is possible that some side effects of Tussigon may not have been reported. These can be reported to the FDA here. Always consult a healthcare professional for medical advice.

Disclaimer: Every effort has been made to ensure that the information provided is accurate, up-to-date and complete, but no guarantee is made to that effect. In addition, the drug information contained herein may be time sensitive and should not be utilized as a reference resource beyond the date hereof. This material does not endorse drugs, diagnose patients, or recommend therapy. This information is a reference resource designed as supplement to, and not a substitute for, the expertise, skill , knowledge, and judgement of healthcare practitioners in patient care. The absence of a warning for a given drug or combination thereof in no way should be construed to indicate safety, effectiveness, or appropriateness for any given patient. Drugs.com does not assume any responsibility for any aspect of healthcare administered with the aid of materials provided. The information contained herein is not intended to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions, or adverse effects. If you have questions about the substances you are taking, check with your doctor, nurse, or pharmacist.

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