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Homatropine / hydrocodone Pregnancy and Breastfeeding Warnings

Homatropine / hydrocodone is also known as: Hycodan, Hydromet, Hydromide, Hydropane, Hydrotropine, Tussigon

Medically reviewed on August 25, 2017

Homatropine / hydrocodone Pregnancy Warnings

Animal studies have not been conducted with this combination product. Babies born to mothers taking opioids regularly during pregnancy may become physically dependent. Opioids given to the mother shortly before delivery may produce some degree of respiratory depression in the newborn, especially if high doses are used. There are no controlled data in human pregnancy.

US FDA pregnancy category C: Animal reproduction studies have shown an adverse effect on the fetus and there are no adequate and well-controlled studies in humans, but potential benefits may warrant use of the drug in pregnant women despite potential risks.

Use is not recommended unless clearly needed

US FDA pregnancy category: C

Comments: Prolonged use of opioids during pregnancy can result in physical dependence in the neonate; women should be advised of the risk of neonatal abstinence syndrome and ensure that appropriate treatment will be available.

See references

Homatropine / hydrocodone Breastfeeding Warnings

A decision should be made to discontinue breastfeeding or discontinue the drug, considering the importance of the drug to the mother

Excreted into human milk: Unknown (homatropine); Yes (hydrocodone)

Comments: Breastfed infants should be closely monitored for increased sedation, difficulty breastfeeding, breathing difficulties, or limpness; mothers should be counseled to seek medical immediate assistance if these develop.

See references

References for pregnancy information

  1. "Product Information. Homatropine Methylbromide-Hydrocodone (homatropine-hydrocodone)." KVK-Tech Inc, Newtown, PA.

References for breastfeeding information

  1. "Product Information. Homatropine Methylbromide-Hydrocodone (homatropine-hydrocodone)." KVK-Tech Inc, Newtown, PA.
  2. United States National Library of Medicine "Toxnet. Toxicology Data Network. Available from: URL: http://toxnet.nlm.nih.gov/cgi-bin/sis/htmlgen?LACT." ([cited 2013 -]):

Further information

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.

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