Skip to Content

Homatropine / hydrocodone Pregnancy and Breastfeeding Warnings

Homatropine / hydrocodone is also known as: Hycodan, Hydromet, Hydromide, Hydropane, Hydrotropine, Tussigon

Homatropine / hydrocodone Pregnancy Warnings

Animal studies have not been conducted with this combination product. Babies born to mothers taking opioids regularly during pregnancy may become physically dependent. Opioids given to the mother shortly before delivery may produce some degree of respiratory depression in the newborn, especially if high doses are used. There are no controlled data in human pregnancy. US FDA pregnancy category C: Animal reproduction studies have shown an adverse effect on the fetus and there are no adequate and well-controlled studies in humans, but potential benefits may warrant use of the drug in pregnant women despite potential risks.

Use is not recommended unless clearly needed US FDA pregnancy category: C Comments: Prolonged use of opioids during pregnancy can result in physical dependence in the neonate; women should be advised of the risk of neonatal abstinence syndrome and ensure that appropriate treatment will be available.

See references

Homatropine / hydrocodone Breastfeeding Warnings

A decision should be made to discontinue breastfeeding or discontinue the drug, considering the importance of the drug to the mother Excreted into human milk: Unknown (homatropine); Yes (hydrocodone) Comments: Breastfed infants should be closely monitored for increased sedation, difficulty breastfeeding, breathing difficulties, or limpness; mothers should be counseled to seek medical immediate assistance if these develop.

See references

References for pregnancy information

  1. "Product Information. Homatropine Methylbromide-Hydrocodone (homatropine-hydrocodone)." KVK-Tech Inc, Newtown, PA.

References for breastfeeding information

  1. "Product Information. Homatropine Methylbromide-Hydrocodone (homatropine-hydrocodone)." KVK-Tech Inc, Newtown, PA.
  2. United States National Library of Medicine "Toxnet. Toxicology Data Network. Available from: URL:" ([cited 2013 -]):

Disclaimer: Every effort has been made to ensure that the information provided by Cerner Multum, Wolters Kluwer Health and is accurate, up-to-date and complete, but no guarantee is made to that effect. In addition, the drug information contained herein may be time sensitive and should not be utilized as a reference resource beyond the date hereof. This material does not endorse drugs, diagnose patients, or recommend therapy. This drug information is a reference resource designed as supplement to, and not a substitute for, the expertise, skill , knowledge, and judgement of healthcare practitioners in patient care. The absence of a warning for a given drug or combination thereof in no way should be construed to indicate that the drug or combination is safe, effective, or appropriate for any given patient. Multum Information Services, Inc. does not assume any responsibility for any aspect of healthcare administered with the aid of information Multum provides. Copyright 2000-2008 Multum Information Services, Inc. The information contained herein is not intended to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions, or adverse effects. If you have questions about the drugs you are taking, check with your doctor, nurse, or pharmacist.