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Trimpex Side Effects

Generic Name: trimethoprim

Note: This document contains side effect information about trimethoprim. Some of the dosage forms listed on this page may not apply to the brand name Trimpex.

For the Consumer

Applies to trimethoprim: oral solution, oral tablet

Along with its needed effects, trimethoprim (the active ingredient contained in Trimpex) may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.

Check with your doctor immediately if any of the following side effects occur while taking trimethoprim:

Less Common

Rare

  • Black, tarry stools
  • blood in urine or stools
  • bluish fingernails, lips, or skin
  • changes in facial skin color
  • chills
  • difficult breathing or shortness of breath
  • fever with or without chills
  • general feeling of discomfort or illness
  • headache
  • joint or muscle pain
  • nausea
  • neck stiffness
  • pale skin
  • pinpoint red spots on skin
  • redness, blistering, burning, tenderness, peeling, or loosening of skin or mucous membranes
  • redness, swelling, or soreness of tongue
  • red skin lesions, often with a purple center
  • sore throat
  • swelling
  • thickened or scaly skin
  • unusual bleeding or bruising
  • unusual tiredness or weakness

Some side effects of trimethoprim may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:

Less Common

For Healthcare Professionals

Applies to trimethoprim: compounding powder, oral solution, oral tablet

Dermatologic

Common (1% to 10%): Rash (e.g., maculopapular, morbilliform, pruritic), pruritus

Rare (less than 0.1%): Photosensitivity, angioedema, erythema multiforme, Stevens Johnson syndrome, toxic epidermal necrolysis (Lyell Syndrome

Frequency not reported: Exfoliative dermatitis, urticaria[Ref]

Gastrointestinal

Common (1% to 10%): Epigastric distress, nausea, vomiting, glossitis, abdominal pain, sore mouth

Frequency not reported: Pseudomembranous colitis, Clostridium difficile associated diarrhea[Ref]

Hematologic

Frequency not reported: Thrombocytopenia, leukopenia, neutropenia, megaloblastic anemia, methemoglobinemia[Ref]

Hepatic

Rare (less than 0.1%): Cholestatic jaundice

Frequency not reported: ALT and AST elevations, elevated bilirubin[Ref]

Hypersensitivity

Rare (less than 0.1%): Anaphylaxis[Ref]

Metabolic

Frequency not reported: Hyperkalemia, hyponatremia[Ref]

Musculoskeletal

Frequency not reported: Myalgia[Ref]

Nervous system

Rare (less than 0.1%): Aseptic meningitis, headache[Ref]

Other

Frequency not reported: Fever[Ref]

Renal

Frequency not reported: Increased BUN, increased serum creatinine[Ref]

References

1. "Product Information. Trimethoprim (trimethoprim)." Teva Pharmaceuticals USA, North Wales, PA.

2. Cerner Multum, Inc. "UK Summary of Product Characteristics." O 0

3. Cerner Multum, Inc. "Australian Product Information." O 0

Further information

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.

Some side effects may not be reported. You may report them to the FDA.

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