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Trimox Side Effects

Generic name: amoxicillin

Medically reviewed by Drugs.com. Last updated on Feb 2, 2022.

Note: This document contains side effect information about amoxicillin. Some dosage forms listed on this page may not apply to the brand name Trimox.

Applies to amoxicillin: oral capsules, oral for suspension, oral tablets.

Side effects include:

Adverse GI effects (e.g., nausea, vomiting, diarrhea), hypersensitivity reactions (e.g., rash).

For Healthcare Professionals

Applies to amoxicillin: oral capsule, oral powder for reconstitution, oral tablet, oral tablet chewable, oral tablet dispersible, oral tablet extended release.

General

The most frequently reported side effects were diarrhea, nausea, and skin rash.[Ref]

Gastrointestinal

Common (1% to 10%): Diarrhea, nausea, abdominal pain

Uncommon (0.1% to 1%): Vomiting

Frequency not reported: Hemorrhagic/pseudomembranous colitis, tooth discolored, black hairy tongue, glossitis, stomatitis

Postmarketing reports: Sore mouth/tongue[Ref]

Dermatologic

Common (1% to 10%): Erythema, exanthema, rash

Uncommon (0.1% to 1%): Urticaria, pruritus

Very rare (less than 0.01%): Angioedema, hypersensitivity vasculitis

Frequency not reported: Erythematous maculopapular rashes, erythema multiforme, Stevens-Johnson Syndrome, bullous dermatitis, exfoliative dermatitis, toxic epidermal necrolysis/Lyell's syndrome, acute generalized exanthematous pustulosis, maculopapular rash, erythema nodosum, pemphigoid reactions[Ref]

Genitourinary

Common (1% to 10%): Vulvovaginal mycotic infection[Ref]

Nervous system

Common (1% to 10%): Headache, taste perversion

Very rare (less than 0.01%): Convulsion, dizziness, hyperkinesia

Frequency not reported: Reversible hyperactivity, central nervous system toxicity, encephalopathy[Ref]

Immunologic

Very rare (less than 0.01%): Anaphylaxis, serum sickness-like reaction

Frequency not reported: Jarisch-Herxheimer reaction[Ref]

Renal

Very rare (less than 0.01%): Crystalluria, interstitial nephritis

Frequency not reported: Nephropathy[Ref]

Hematologic

Very rare (less than 0.01%): Leucopenia, severe neutropenia, agranulocytosis, hemolytic anemia, thrombocytopenia, bleeding time prolonged, prothrombin time prolonged

Frequency not reported: Anemia, thrombocytopenic purpura, eosinophilia, platelet function defective, lymphadenopathy[Ref]

Other

Common (1% to 10%): Candidiasis, fungal/mycotic infection

Very rare (less than 0.01%): Mucocutaneous candidiasis

Frequency not reported: Intestinal candidiasis, oral moniliasis, vaginal moniliasis, fever, chills[Ref]

Hepatic

Very rare (less than 0.01%): Hepatitis, cholestatic jaundice, AST increased, ALT increased

Frequency not reported: Hepatic dysfunction, hepatic cholestasis, acute cytolytic hepatitis[Ref]

Respiratory

Frequency not reported: Bronchospasm, acute severe dyspnea, pneumonitis allergic[Ref]

Local

Frequency not reported: Phlebitis, injection site pain[Ref]

Metabolic

Frequency not reported: Electrolyte disturbance, hypokalemia[Ref]

Musculoskeletal

Frequency not reported: Joint pain, arthralgia[Ref]

Psychiatric

Frequency not reported: Agitation, anxiety, insomnia, confusion, behavior changed, hallucination[Ref]

Frequently asked questions

References

1. "Product Information. Amoxil (amoxicillin)." SmithKline Beecham (2001):

2. Cerner Multum, Inc. "UK Summary of Product Characteristics." O 0

3. Cerner Multum, Inc. "Australian Product Information." O 0

4. "Product Information. Moxatag (amoxicillin)." Fera Pharmaceuticals (2017):

Further information

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.

Some side effects may not be reported. You may report them to the FDA.

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