Medically reviewed by Drugs.com. Last updated on Jul 12, 2021.
The Trimox brand name has been discontinued in the U.S. If generic versions of this product have been approved by the FDA, there may be generic equivalents available.
What is Trimox?
Trimox (amoxicillin) is a penicillin antibiotic that fights bacteria.
Amoxicillin is also sometimes used together with another antibiotic called clarithromycin (Biaxin) to treat stomach ulcers caused by Helicobacter pylori infection. This combination is sometimes used with a stomach acid reducer called lansoprazole (Prevacid).
Trimox may also be used for purposes not listed in this medication guide.
Do not use Trimox if you are allergic to amoxicillin or to any other penicillin antibiotic, such as ampicillin (Omnipen, Principen), dicloxacillin (Dycill, Dynapen), oxacillin (Bactocill), penicillin (Beepen-VK, Ledercillin VK, Pen-V, Pen-Vee K, Pfizerpen, V-Cillin K, Veetids), and others.
Before using Trimox, tell your doctor if you are allergic to cephalosporins such as Ceclor, Ceftin, Duricef, Keflex, and others. Also tell your doctor if you have asthma, liver or kidney disease, a bleeding or blood clotting disorder, mononucleosis (also called "mono"), or any type of allergy.
Trimox can make birth control pills less effective, which may result in pregnancy. Before taking amoxicillin, tell your doctor if you use birth control pills.
Take Trimox for the entire length of time prescribed by your doctor. Your symptoms may get better before the infection is completely treated.
Trimox will not treat a viral infection such as the common cold or flu. Do not give Trimox to another person, even if they have the same symptoms you do.
Antibiotic medicines can cause diarrhea, which may be a sign of a new infection. If you have diarrhea that is watery or has blood in it, call your doctor. Do not use any medicine to stop the diarrhea unless your doctor has told you to.
Before taking this medicine
You should not use this medicine if you are allergic to any penicillin antibiotic, such as ampicillin, dicloxacillin, oxacillin, penicillin, or ticarcillin.
To make sure Trimox is safe for you, tell your doctor if you have:
liver or kidney disease;
mononucleosis (also called "mono");
a history of diarrhea caused by taking antibiotics; or
food or drug allergies (especially to a cephalosporin antibiotic such as Omnicef, Cefzil, Ceftin, Keflex, and others).
If you are being treated for gonorrhea, your doctor may also have you tested for syphilis, another sexually transmitted disease.
Trimox is not expected to harm an unborn baby. Tell your doctor if you are pregnant or plan to become pregnant during treatment.
Trimox can make birth control pills less effective. Ask your doctor about using non hormonal birth control (condom, diaphragm with spermicide) to prevent pregnancy while taking Trimox.
Amoxicillin can pass into breast milk and may harm a nursing baby. Tell your doctor if you are breast-feeding a baby.
How should I take Trimox?
Take Trimox exactly as it was prescribed for you. Follow all directions on your prescription label. Do not take this medicine in larger or smaller amounts or for longer than recommended.
Take this medicine at the same time each day.
You may need to shake Trimox liquid well just before you measure a dose. Follow the directions on your medicine label.
Measure liquid Trimox medicine with the dosing syringe provided, or with a special dose-measuring spoon or medicine cup. If you do not have a dose-measuring device, ask your pharmacist for one. You may place the liquid directly on the tongue, or you may mix it with water, milk, baby formula, fruit juice, or ginger ale. Drink all of the mixture right away. Do not save any for later use.
Do not crush, chew, or break an extended-release tablet. Swallow it whole.
While using Trimox, you may need frequent blood tests. Your kidney and liver function may also need to be checked.
If you are taking Trimox with clarithromycin and/or lansoprazole to treat stomach ulcer, use all of your medications as directed. Read the medication guide or patient instructions provided with each medication. Do not change your doses or medication schedule without your doctor's advice.
Use this medicine for the full prescribed length of time. Your symptoms may improve before the infection is completely cleared. Skipping doses may also increase your risk of further infection that is resistant to antibiotics. Amoxicillin will not treat a viral infection such as the flu or a common cold.
Do not share this medicine with another person, even if they have the same symptoms you have.
This medicine can cause unusual results with certain medical tests. Tell any doctor who treats you that you are using Trimox.
Store at room temperature away from moisture, heat, and light.
You may store liquid Trimox in a refrigerator but do not allow it to freeze. Throw away any liquid Trimox that is not used within 14 days after it was mixed at the pharmacy.
What happens if I miss a dose?
Take the missed dose as soon as you remember. Skip the missed dose if it is almost time for your next scheduled dose. Do not take extra medicine to make up the missed dose.
What happens if I overdose?
Seek emergency medical attention or call the Poison Help line at 1-800-222-1222.
Overdose symptoms may include confusion, behavior changes, a severe skin rash, urinating less than usual, or seizure (black-out or convulsions).
What to avoid
Antibiotic medicines can cause diarrhea, which may be a sign of a new infection. If you have diarrhea that is watery or bloody, stop using Trimox and call your doctor. Do not use anti-diarrhea medicine unless your doctor tells you to.
Trimox side effects
Get emergency medical help if you have any of these signs of an allergic reaction to Trimox: hives; difficulty breathing; swelling of your face, lips, tongue, or throat.
Call your doctor at once if you have:
diarrhea that is watery or bloody;
fever, swollen gums, painful mouth sores, pain when swallowing, skin sores, cold or flu symptoms, cough, trouble breathing;
swollen glands, rash or itching, joint pain, or general ill feeling;
pale or yellowed skin, yellowing of the eyes, dark colored urine, fever, confusion or weakness;
severe tingling, numbness, pain, muscle weakness;
easy bruising, unusual bleeding (nose, mouth, vagina, or rectum), purple or red pinpoint spots under your skin; or
severe skin reaction--fever, sore throat, swelling in your face or tongue, burning in your eyes, skin pain, followed by a red or purple skin rash that spreads (especially in the face or upper body) and causes blistering and peeling.
Common Trimox side effects may include:
stomach pain, nausea, vomiting, diarrhea;
vaginal itching or discharge;
swollen, black, or "hairy" tongue.
This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.
What other drugs will affect Trimox?
Other drugs may interact with amoxicillin, including prescription and over-the-counter medicines, vitamins, and herbal products. Tell each of your health care providers about all medicines you use now and any medicine you start or stop using.
There are several antibiotics that kill the common mouth bacteria that cause tooth infections. The best (first-line) antibiotics for tooth infection include: Amoxicillin, Penicillin, Cephalexin, Clindamycin, Azithromycin. Amoxicillin is often the first choice because it is widely effective and has the fewest gastrointestinal side effects. Continue reading
Yes, you can drink alcohol while taking the antibiotic amoxicillin. The alcohol will not stop amoxicillin from working. However, many health professionals will recommend you avoid alcohol to give your body the best chance possible to fight the infection. Moderation is key. Continue reading
Amoxicillin capsules and tablets have an expiry of around 2 years and, provided they are stored as recommended and in the original packaging, there will be a small lee way of safety if used beyond expiry. Amoxicillin suspension is different and has a very short shelf life of about 7-10 days once it is prepared. Continue reading
No, you should not take amoxicillin if you are allergic to penicillin. Amoxicillin belongs to the Penicillin class of antibiotics and must be avoided. You need to see your dentist and/or doctor with an infected tooth. Continue reading
The main difference between amoxicillin and penicillin is that amoxicillin is effective against a wider spectrum of bacteria compared with penicillin. Both amoxicillin and penicillin belong to the class of antibiotics called penicillins. Continue reading
- What are the best antibiotics for pneumonia?
- Amoxicillin for ear infection: Take how many times a day?
More about Trimox (amoxicillin)
- Side Effects
- During Pregnancy or Breastfeeding
- Dosage Information
- Drug Images
- Drug Interactions
- Drug class: aminopenicillins
Related treatment guides
Remember, keep this and all other medicines out of the reach of children, never share your medicines with others, and use Trimox only for the indication prescribed.
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.
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