Triferic Side Effects
Generic name: ferric pyrophosphate
Medically reviewed by Drugs.com. Last updated on Feb 5, 2025.
Note: This document provides detailed information about Triferic Side Effects associated with ferric pyrophosphate. Some dosage forms listed on this page may not apply specifically to the brand name Triferic.
Applies to ferric pyrophosphate: route not applicable powder for solution, route not applicable solution.
Serious side effects of Triferic
Along with its needed effects, ferric pyrophosphate (the active ingredient contained in Triferic) may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.
Check with your doctor or nurse immediately if any of the following side effects occur while taking ferric pyrophosphate:
More common side effects
- bloating or swelling of the face, arms, hands, lower legs, or feet
- blurred vision
- confusion
- dizziness, faintness, or lightheadedness when getting up suddenly from a lying or sitting position
- rapid weight gain
- sweating
- tingling of the hands or feet
- trouble breathing
- unusual tiredness or weakness
- unusual weight gain or loss
Less common side effects
- bladder pain
- bloody or cloudy urine
- difficult, burning, or painful urination
- fever
- frequent urge to urinate
- lower back or side pain
Incidence not known
Other side effects of Triferic
Some side effects of ferric pyrophosphate may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects.
Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:
Less common side effects
- back pain
- lack or loss of strength
Other side effects of Triferic
Some side effects of ferric pyrophosphate may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects.
Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:
For healthcare professionals
Applies to ferric pyrophosphate: parenteral powder for injection, parenteral solution.
Cardiovascular adverse events
- Very common (10% or more): Procedural hypotension (21.6%)
- Common (1% to 10%): Arteriovenous fistula thrombosis, arteriovenous fistula sight hemorrhage
- Frequency not reported: Intradialytic hypotension[Ref]
Nervous system
- Common (1% to 10%): Headache
- Frequency not reported: Dizziness[Ref]
Other
Hypersensitivity
- Uncommon (0.1% to 1%): Hypersensitivity[Ref]
Respiratory
Immunologic
- Common (1% to 10%): Urinary tract infection[Ref]
Gastrointestinal
- Frequency not reported: Constipation, nausea[Ref]
Dermatologic
Musculoskeletal
- Common (1% to 10%): Muscle spasms, pain in extremity, back pain[Ref]
References
1. (2012) "Product Information. Voraxaze (glucarpidase)." BTG International Inc
More about Triferic (ferric pyrophosphate)
- Check interactions
- Compare alternatives
- Reviews (1)
- Dosage information
- During pregnancy
- FDA approval history
- Drug class: iron products
- Breastfeeding
- En español
Patient resources
Other brands
Professional resources
Other brands
Related treatment guides
Further information
Triferic side effects can vary depending on the individual. Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.
Note: Medication side effects may be underreported. If you are experiencing side effects that are not listed, submit a report to the FDA by following this guide.