Triferic Side Effects

Generic name: ferric pyrophosphate

Medically reviewed by Drugs.com. Last updated on Mar 8, 2022.

Note: This document contains side effect information about ferric pyrophosphate. Some of the dosage forms listed on this page may not apply to the brand name Triferic.

In Summary

More frequent side effects include: urinary tract infection. See below for a comprehensive list of adverse effects.

For the Consumer

Applies to ferric pyrophosphate: route not applicable powder for solution, route not applicable solution

Side effects requiring immediate medical attention

Along with its needed effects, ferric pyrophosphate (the active ingredient contained in Triferic) may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.

Check with your doctor or nurse immediately if any of the following side effects occur while taking ferric pyrophosphate:

More common

• Bloating or swelling of the face, arms, hands, lower legs, or feet
• blurred vision
• confusion
• dizziness, faintness, or lightheadedness when getting up suddenly from a lying or sitting position
• rapid weight gain
• sweating
• tingling of the hands or feet
• trouble breathing
• unusual tiredness or weakness
• unusual weight gain or loss

Less common

• Bladder pain
• bloody or cloudy urine
• difficult, burning, or painful urination
• fever
• frequent urge to urinate
• lower back or side pain

Incidence not known

• Cough
• difficulty with breathing or swallowing
• hives, itching, or skin rash
• nausea
• puffiness or swelling of the eyelids or around the eyes, face, lips, or tongue
• reddening of the skin, especially around the ears
• swelling of the eyes, face, or inside of the nose
• tightness in the chest

Side effects not requiring immediate medical attention

Some side effects of ferric pyrophosphate may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects.

Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:

More common

• Headache
• muscle spasms
• pain in the arms or legs

Less common

• Back pain
• lack or loss of strength

Side effects not requiring immediate medical attention

Some side effects of ferric pyrophosphate may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects.

Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:

For Healthcare Professionals

Applies to ferric pyrophosphate: parenteral powder for injection, parenteral solution

Cardiovascular

Very common (10% or more): Procedural hypotension (21.6%)

Common (1% to 10%): Arteriovenous fistula thrombosis, arteriovenous fistula sight hemorrhage

Frequency not reported: Intradialytic hypotension^[Ref]

Nervous system

Common (1% to 10%): Headache

Frequency not reported: Dizziness^[Ref]

Other

Common (1% to 10%): Peripheral edema, pyrexia, asthenia, fatigue^[Ref]

Hypersensitivity

Uncommon (0.1% to 1%): Hypersensitivity^[Ref]

Respiratory

Common (1% to 10%): Dyspnea^[Ref]

Immunologic

Common (1% to 10%): Urinary tract infection^[Ref]

Gastrointestinal

Frequency not reported: Constipation, nausea^[Ref]

Dermatologic

Frequency not reported: Pruritus^[Ref]

Musculoskeletal

Common (1% to 10%): Muscle spasms, pain in extremity, back pain^[Ref]

Further information

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.

Some side effects may not be reported. You may report them to the FDA.

Medical Disclaimer