Triferic Side Effects
Generic Name: ferric pyrophosphate
Medically reviewed by Drugs.com. Last updated on May 3, 2020.
Note: This document contains side effect information about ferric pyrophosphate. Some of the dosage forms listed on this page may not apply to the brand name Triferic.
In Summary
More frequent side effects include: urinary tract infection. See below for a comprehensive list of adverse effects.
For the Consumer
Applies to ferric pyrophosphate: route not applicable powder for solution, route not applicable solution
Side effects requiring immediate medical attention
Along with its needed effects, ferric pyrophosphate (the active ingredient contained in Triferic) may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.
Check with your doctor or nurse immediately if any of the following side effects occur while taking ferric pyrophosphate:
More common
- Bloating or swelling of the face, arms, hands, lower legs, or feet
- blurred vision
- confusion
- dizziness, faintness, or lightheadedness when getting up suddenly from a lying or sitting position
- rapid weight gain
- sweating
- tingling of the hands or feet
- trouble breathing
- unusual tiredness or weakness
- unusual weight gain or loss
Less common
- Bladder pain
- bloody or cloudy urine
- difficult, burning, or painful urination
- fever
- frequent urge to urinate
- lower back or side pain
Incidence not known
- Cough
- difficulty with breathing or swallowing
- hives, itching, or skin rash
- nausea
- puffiness or swelling of the eyelids or around the eyes, face, lips, or tongue
- reddening of the skin, especially around the ears
- swelling of the eyes, face, or inside of the nose
- tightness in the chest
Side effects not requiring immediate medical attention
Some side effects of ferric pyrophosphate may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects.
Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:
More common
- Headache
- muscle spasms
- pain in the arms or legs
Less common
- Back pain
- lack or loss of strength
Side effects not requiring immediate medical attention
Some side effects of ferric pyrophosphate may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects.
Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:
For Healthcare Professionals
Applies to ferric pyrophosphate: parenteral powder for injection, parenteral solution
Cardiovascular
Very common (10% or more): Procedural hypotension (21.6%)
Common (1% to 10%): Arteriovenous fistula thrombosis, arteriovenous fistula sight hemorrhage
Frequency not reported: Intradialytic hypotension[Ref]
Nervous system
Common (1% to 10%): Headache
Frequency not reported: Dizziness[Ref]
Other
Common (1% to 10%): Peripheral edema, pyrexia, asthenia, fatigue[Ref]
Hypersensitivity
Uncommon (0.1% to 1%): Hypersensitivity[Ref]
Respiratory
Common (1% to 10%): Dyspnea[Ref]
Immunologic
Common (1% to 10%): Urinary tract infection[Ref]
Gastrointestinal
Frequency not reported: Constipation, nausea[Ref]
Dermatologic
Frequency not reported: Pruritus[Ref]
Musculoskeletal
Common (1% to 10%): Muscle spasms, pain in extremity, back pain[Ref]
References
1. "Product Information. Voraxaze (glucarpidase)." BTG International Inc, West Conshohocken, PA.
More about Triferic (ferric pyrophosphate)
- During Pregnancy or Breastfeeding
- Dosage Information
- Drug Interactions
- Pricing & Coupons
- En Español
- 1 Review
- Drug class: iron products
- FDA Approval History
Consumer resources
- Other brands
- Triferic AVNU
Professional resources
Related treatment guides
Further information
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.
Some side effects may not be reported. You may report them to the FDA.