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Feraheme

Generic Name: ferumoxytol (FER ue MOX i tol)
Brand Names: Feraheme

Medically reviewed on Jul 3, 2018

What is Feraheme?

Feraheme (ferumoxytol) is a type of iron. You normally get iron from the foods you eat. In your body, iron becomes a part of your hemoglobin (HEEM o glo bin) and myoglobin (MY o glo bin). Hemoglobin carries oxygen through your blood to tissues and organs. Myoglobin helps your muscle cells store oxygen.

Feraheme is used to treat iron deficiency anemia (a lack of red blood cells caused by having too little iron in the body).

Feraheme injection is used in people with chronic kidney disease, or in people unable to take oral iron (by mouth) or who have not responded well to oral iron

Important information

You should not use Feraheme if you have ever had an allergic reaction to an injectable form of iron (including ferumoxytol), or if you have iron overload syndrome or any type of anemia that is not caused by iron deficiency.

Feraheme can cause severe and sometimes fatal allergic reactions, even if you have used this medicine before without any reaction. Get emergency medical help if you have hives, itching, wheezing, trouble breathing, swelling in your face or throat, or feeling like you might pass out. Watch for signs of allergic reaction for at least 30 minutes after your injection.

Feraheme can cause unusual results with magnetic resonance imaging (MRI) tests for up to 3 months after you receive this medication. Tell any doctor who treats you that you have received a ferumoxytol injection within the past 3 months.

Feraheme will not affect other types of X-rays, CT scans, ultrasounds, or nuclear radiation imaging.

Before taking this medicine

You should not use Feraheme if:

  • you have had an allergic reaction to an injectable form of iron (including ferumoxytol);

  • you have any type of anemia that is not caused by iron deficiency.

To make sure Feraheme is safe for you, tell your doctor if you have ever had:

  • iron load syndrome;

  • any drug allergies; or

  • low blood pressure.

It is not known whether Feraheme will harm an unborn baby. Tell your doctor if you are pregnant.

It is not known whether ferumoxytol passes into breast milk or if it could harm a nursing baby. You should not breast-feed while using this medicine.

How is Feraheme given?

Feraheme is given as an infusion into a vein (IV). A healthcare provider will give you this injection, which can take up to 15 minutes to complete.

You will be watched closely for at least 30 minutes after receiving the injection, to make sure you do not have an allergic reaction to the medicine.

Feraheme is usually given as a single injection followed by a second injection 3 to 8 days later.

You may need frequent medical tests to help your doctor determine how long to treat you with Feraheme.

Feraheme can cause unusual results with magnetic resonance imaging (MRI) tests for up to 3 months after you receive this medication. After you receive a Feraheme injection, you should wait at least 4 weeks before having an MRI. Tell any doctor who treats you that you have received a ferumoxytol injection.

Feraheme will not affect other types of X-rays, CT scans, ultrasounds, or nuclear radiation imaging.

Feraheme dosing information

Usual Adult Dose for Iron Deficiency Anemia:

Initial dose: 510 mg, IV, over at least 15 minutes
Second dose: 510 mg, IV, over at least 15 minutes, 3 to 8 days after the initial dose

Comments:
-The patient should be reclined or semi-reclined during administration.
-Evaluate hematologic response at least one month after the second infusion.
-May be readministered for persistent or recurrent iron deficiency anemia.

Use: Iron deficiency anemia in adult patients with chronic kidney disease.

What happens if I miss a dose?

Call your doctor for instructions if you miss an appointment for your injection.

What happens if I overdose?

Seek emergency medical attention or call the Poison Help line at 1-800-222-1222.

What should I avoid while receiving Feraheme?

Follow your doctor's instructions about any restrictions on food, beverages, or activity.

Do not take any vitamin or mineral supplements that your doctor has not prescribed or recommended.

Feraheme side effects

Get emergency medical help if you have signs of an allergic reaction to Feraheme: hives, itching; wheezing, difficult breathing; feeling like you might pass out; swelling of your face, lips, tongue, or throat.

Watch for signs of allergic reaction for at least 30 minutes after your injection.

Older adults who have other health problems may be more likely to have a severe allergic reaction to Feraheme.

Call your doctor at once if you have:

  • severe dizziness or light-headed feeling;

  • slow heart rate, weak pulse, slow breathing; or

  • worsening symptoms of kidney failure.

Common Feraheme side effects may include:

  • headache;

  • diarrhea, constipation;

  • nausea; or

  • swelling in your arms, hands, legs, or feet.

What other drugs will affect Feraheme?

Tell your doctor if you are also taking an oral iron supplement (including ferrous gluconate, ferrous fumarate, or ferrous sulfate).

Other drugs may interact with ferumoxytol, including prescription and over-the-counter medicines, vitamins, and herbal products. Tell each of your health care providers about all medicines you use now and any medicine you start or stop using.

Further information

Remember, keep this and all other medicines out of the reach of children, never share your medicines with others, and use Feraheme only for the indication prescribed.

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.

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