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Triaprin Side Effects

Generic Name: acetaminophen / butalbital

Note: This page contains side effects data for the generic drug acetaminophen / butalbital. It is possible that some of the dosage forms included below may not apply to the brand name Triaprin.

For the Consumer

Applies to acetaminophen / butalbital: capsules, tablets

Check with your doctor if any of these most COMMON side effects persist or become bothersome:

Dizziness; drowsiness; light-headedness; mild stomach pain; nausea; vomiting.

Seek medical attention right away if any of these SEVERE side effects occur while taking acetaminophen / butalbital:

Severe allergic reactions (rash; hives; itching; difficulty breathing or swallowing; tightness in the chest; swelling of the mouth, face, lips, throat, or tongue); confusion; fainting; fast heartbeat; fever, chills, or persistent sore throat; intoxicated feeling; mental or mood changes; numbness or tingling; red, swollen, blistered, or peeling skin; seizures; severe or persistent drowsiness; shortness of breath; sluggishness; symptoms of liver problems (eg, dark urine, loss of appetite, pale stools, severe stomach pain; yellowing of the skin or eyes); unusual bruising or bleeding; unusual tiredness or weakness.

For Healthcare Professionals

Applies to acetaminophen / butalbital: oral capsule, oral tablet

General

The most frequently reported adverse events have included drowsiness, lightheadedness, dizziness, sedation, shortness of breath, nausea, vomiting, abdominal pain, and intoxicated feeling.[Ref]

Hepatic

Acetaminophen:
Frequency not reported: Liver failure[Ref]

Acute liver failure has been reported with acetaminophen use; many case have been associated with use at doses in excess of 4 g/day, and often involving more than 1 acetaminophen-containing product.[Ref]

Hypersensitivity

Butalbital-Acetaminophen:
Uncommon (0.1% to 1%): Allergic reactions
Postmarketing reports: Anaphylaxis

Acetaminophen:
Postmarketing reports: Anaphylaxis[Ref]

Dermatologic

Butalbital-Acetaminophen:
Uncommon (0.1% to 1%): Hyperhidrosis, pruritus
Frequency not reported: Toxic epidermal necrolysis, erythema multiforme

Acetaminophen:
Rare (less than 0.1%): Serious skin reactions such as acute generalized exanthematous pustulosis, Stevens-Johnson syndrome, and toxic epidermal necrolysis
Frequency not reported: Rash[Ref]

Several cases of dermatologic reactions including toxic epidermal necrolysis and erythema multiforme have been reported.[Ref]

Psychiatric

Uncommon (0.1% to 1%): Agitation, euphoria[Ref]

Nervous system

Common (1% to 10%): Drowsiness, lightheadedness, dizziness, sedation
Uncommon (0.1% to 1%): Headache, shaky feeling, tingly, fainting, numbness, seizures, mental confusion, excitement or depression due to intolerance[Ref]

Respiratory

Common (1% to 10%): Shortness of breath
Uncommon (0.1% to 1%): Nasal congestion[Ref]

Gastrointestinal

Common (1% to 10%): Nausea, vomiting, abdominal pain
Uncommon (0.1% to 1%): Dry mouth, difficulty swallowing, heartburn, flatulence, constipation[Ref]

Hematologic

Acetaminophen:
Frequency not reported: Thrombocytopenia, agranulocytosis[Ref]

Cardiovascular

Uncommon (0.1% to 1%): Tachycardia[Ref]

Musculoskeletal

Uncommon (0.1% to 1%): Leg pain, muscle fatigue[Ref]

Other

Common (1% to 10%): Intoxicated feeling
Uncommon (0.1% to 1%): Fatigue, high energy, heavy eyelids, sluggishness, hot spells, fever, earache, tinnitus[Ref]

Renal

Uncommon (0.1% to 1%): Diuresis,[Ref]

References

1. "Product Information. Allzital (acetaminophen-butalbital)." Skylar Laboratories, Canton, MS.

It is possible that some side effects of Triaprin may not have been reported. These can be reported to the FDA here. Always consult a healthcare professional for medical advice.

More about Triaprin (acetaminophen / butalbital)

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Disclaimer: Every effort has been made to ensure that the information provided is accurate, up-to-date and complete, but no guarantee is made to that effect. In addition, the drug information contained herein may be time sensitive and should not be utilized as a reference resource beyond the date hereof. This material does not endorse drugs, diagnose patients, or recommend therapy. This information is a reference resource designed as supplement to, and not a substitute for, the expertise, skill , knowledge, and judgement of healthcare practitioners in patient care. The absence of a warning for a given drug or combination thereof in no way should be construed to indicate safety, effectiveness, or appropriateness for any given patient. Drugs.com does not assume any responsibility for any aspect of healthcare administered with the aid of materials provided. The information contained herein is not intended to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions, or adverse effects. If you have questions about the substances you are taking, check with your doctor, nurse, or pharmacist.

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