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Tirofiban Side Effects

Medically reviewed by Drugs.com. Last updated on Mar 24, 2024.

Applies to tirofiban: intravenous solution.

Serious side effects of tirofiban

Along with its needed effects, tirofiban may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.

Check with your doctor or nurse immediately if any of the following side effects occur while taking tirofiban:

More common side effects

  • abdominal or stomach pain or swelling
  • arm, back, or jaw pain
  • black, tarry stools
  • blood in the eyes
  • blood in the urine
  • bruising or purple areas on the skin
  • chest pain or discomfort
  • chest tightness or heaviness
  • coughing up blood
  • decreased alertness
  • fast or irregular heartbeat
  • headache
  • joint pain or swelling
  • nausea
  • nosebleeds

Less common side effects

  • bleeding gums
  • lightheadedness or fainting
  • pinpoint red spots on the skin
  • severe, unusual tiredness or weakness
  • slow heartbeat
  • swelling of the hands, ankles, feet, or lower legs

Incidence not known

Other side effects of tirofiban

Some side effects of tirofiban may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects.

Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:

More common side effects

  • pain in the legs or hips

Less common side effects

  • dizziness
  • sweating

For healthcare professionals

Applies to tirofiban: intravenous powder for injection, intravenous solution.

General adverse events

Bleeding is the most common adverse reaction. Clinical trial adverse reactions were reported in patients taking this drug in addition to heparin.[Ref]

Hematologic

Nervous system

Cardiovascular

Gastrointestinal

Other

Dermatologic

Genitourinary

Musculoskeletal

Immunologic

Respiratory

References

1. (2001) "Product Information. Aggrastat (tirofiban)." Merck & Co., Inc

2. Cerner Multum, Inc. "UK Summary of Product Characteristics."

3. Cerner Multum, Inc. "Australian Product Information."

Further information

Tirofiban side effects can vary depending on the individual. Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.

Note: Medication side effects may be underreported. If you are experiencing side effects that are not listed, submit a report to the FDA by following this guide.