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Stiolto Respimat Side Effects

Generic Name: olodaterol / tiotropium

Note: This page contains side effects data for the generic drug olodaterol / tiotropium. It is possible that some of the dosage forms included below may not apply to the brand name Stiolto Respimat.

For the Consumer

Applies to olodaterol / tiotropium: inhalation spray

As well as its needed effects, olodaterol / tiotropium may cause unwanted side effects that require medical attention.

Major Side Effects

If any of the following side effects occur while taking olodaterol / tiotropium, check with your doctor immediately:

Less common or rare:
  • Bladder pain
  • blindness
  • bloody or cloudy urine
  • blurred vision
  • confusion
  • decrease in the frequency of urination
  • decrease in urine volume
  • decreased urination
  • decreased vision
  • difficult, burning, or painful urination
  • difficulty in passing urine (dribbling)
  • dizziness
  • dry mouth
  • eye pain
  • fainting
  • fast or irregular heartbeat
  • fever
  • frequent urge to urinate
  • headache
  • hives, itching, or rash
  • hoarseness
  • increase in heart rate
  • irritation
  • joint pain, stiffness, or swelling
  • lightheadedness
  • lower back or side pain
  • nausea or vomiting
  • nervousness
  • pounding in the ears
  • rapid breathing
  • redness of the skin
  • slow or fast heartbeat
  • sunken eyes
  • swelling of the eyelids, face, lips, hands, or feet
  • tearing
  • thirst
  • tightness in the chest
  • troubled breathing or swallowing
  • unusual tiredness or weakness
  • wrinkled skin
Incidence not known:
  • Cough
  • eye pain or discomfort
  • large, hive-like swelling on the face, eyelids, lips, tongue, throat, hands, legs, feet, or sex organs
  • puffiness or swelling of the eyelids or around the eyes, face, lips, or tongue
  • visual halos or colored images

Minor Side Effects

Some olodaterol / tiotropium side effects may not need any medical attention. As your body gets used to the medicine these side effects may disappear. Your health care professional may be able to help you prevent or reduce these side effects, but do check with them if any of the following side effects continue, or if you are concerned about them:

More common:
  • Muscle aches
  • sore throat
  • stuffy or runny nose
Less common:
  • Back pain
Less common or rare:
  • Bleeding gums
  • bloody nose
  • creamy white, curd-like patches in the mouth or throat
  • difficulty having a bowel movement (stool)
  • difficulty with moving
  • dry skin
  • heartburn
  • irritation in the mouth
  • mouth ulcers
  • muscle pain or stiffness
  • pain in the joints
  • pain or tenderness around the eyes and cheekbones
  • pain when eating or swallowing
  • redness and swelling of the gums
  • redness, swelling, or soreness of the tongue
  • swelling or inflammation of the mouth
  • trouble sleeping
  • voice changes

For Healthcare Professionals

Applies to olodaterol / tiotropium: inhalation aerosol

General

The most common serious adverse reactions were COPD exacerbation and pneumonia.[Ref]

Respiratory

Common (1% to 10%): Nasopharyngitis, cough, epistaxis, pharyngitis, dysphonia, bronchospasm, laryngitis, sinusitis[Ref]

Cardiovascular

Common (1% to 10%): Atrial fibrillation, palpitations, supraventricular tachycardia[Ref]

Dermatologic

Common (1% to 10%): Rash, pruritus, angioneurotic edema, urticaria, skin infection, and skin ulcer, dry skin[Ref]

Gastrointestinal

Common (1% to 10%): Dry mouth, constipation, oropharyngeal candidiasis, dysphagia, gastroesophageal reflux disease, gingivitis, glossitis, stomatitis, intestinal obstruction including ileus paralytic[Ref]

Genitourinary

Common (1% to 10%): Urinary retention, dysuria, urinary tract infection

Hypersensitivity

Common (1% to 10%): Immediate hypersensitivity reactions[Ref]

Metabolic

Common (1% to 10%): Dehydration[Ref]

Musculoskeletal

Common (1% to 10%): Back pain, arthralgia, joint swelling[Ref]

Nervous system

Common (1% to 10%): Dizziness, insomnia[Ref]

Ocular

Common (1% to 10%): Glaucoma, increased intraocular pressure, blurred vision[Ref]

References

1. "Product Information. Stiolto Respimat (olodaterol-tiotropium)." Boehringer Ingelheim, Ridgefield, CT.

It is possible that some side effects of Stiolto Respimat may not have been reported. These can be reported to the FDA here. Always consult a healthcare professional for medical advice.

Disclaimer: Every effort has been made to ensure that the information provided is accurate, up-to-date and complete, but no guarantee is made to that effect. In addition, the drug information contained herein may be time sensitive and should not be utilized as a reference resource beyond the date hereof. This material does not endorse drugs, diagnose patients, or recommend therapy. This information is a reference resource designed as supplement to, and not a substitute for, the expertise, skill , knowledge, and judgement of healthcare practitioners in patient care. The absence of a warning for a given drug or combination thereof in no way should be construed to indicate safety, effectiveness, or appropriateness for any given patient. Drugs.com does not assume any responsibility for any aspect of healthcare administered with the aid of materials provided. The information contained herein is not intended to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions, or adverse effects. If you have questions about the substances you are taking, check with your doctor, nurse, or pharmacist.

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