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Somnote Side Effects

Generic Name: chloral hydrate

Note: This document contains side effect information about chloral hydrate. Some of the dosage forms listed on this page may not apply to the brand name Somnote.

For the Consumer

Applies to chloral hydrate: oral capsules, oral solution, rectal suppositories

Side effects include:

Nausea, vomiting, diarrhea, ataxia, dizziness.

For Healthcare Professionals

Applies to chloral hydrate: compounding powder, oral capsule, oral syrup, rectal suppository


Gastrointestinal side effects including nausea, vomiting, and diarrhea have been the most frequent side effects associated with the use of chloral hydrate (the active ingredient contained in Somnote) [Ref]

Nervous system

Nervous system side effects including ataxia and dizziness have been reported. Residual sedation has been reported infrequently following usual hypnotic doses. A somnambulistic reaction characterized by disorientation and incoherence has been reported rarely.[Ref]


Dermatologic side effects including scarlatiniform or erythematous rash, urticaria, angioedema, purpura, eczema, bullous lesions, and erythema multiforme have been reported.[Ref]


1. "PDR Generics." Montvale, NJ: Medical Economics (1995):

Further information

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.

Some side effects may not be reported. You may report them to the FDA.