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Somnote Side Effects

Generic name: chloral hydrate

Medically reviewed by Last updated on Jul 24, 2022.

Note: This document contains side effect information about chloral hydrate. Some of the dosage forms listed on this page may not apply to the brand name Somnote.

Applies to chloral hydrate: compounding powder, oral capsule, oral syrup, rectal suppository


Frequency not reported: Torsades de pointes, hypotension, ventricular and atrial arrhythmias, depression of myocardial contractility, shortening of refractory period[Ref]


Frequency not reported: Scarlatiniform exanthema, erythematous rash, urticaria, purpura, eczema, bullous lesions, erythema multiforme[Ref]


Frequency not reported: Gastric irritation, nausea, vomiting, abdominal distension, diarrhea, stomach pain, unpleasant taste, flatulence, ileus[Ref]


Frequency not reported: Ketonuria[Ref]


Frequency not reported: Leucopenia, eosinophilia[Ref]


Frequency not reported: Allergic skin reactions, angioedema[Ref]


Frequency not reported: Porphyria[Ref]

Nervous system

Frequency not reported: Headache, unusual/paradoxical excitement, drowsiness, residual sedation/hangover, somnambulism, disorientation, incoherence, delirium, staggering gait, ataxia, lightheadedness, vertigo, dizziness, confusion, coma[Ref]


Frequency not reported: Ptosis, allergic conjunctivitis, keratoconjunctivitis[Ref]


Frequency not reported: Tolerance, hypothermia, malaise, fever, middle ear pressure[Ref]


Frequency not reported: Paranoia, hallucinations, nightmares[Ref]


Frequency not reported: Respiratory depression, laryngeal edema, respiratory obstruction[Ref]


1. Cerner Multum, Inc. "UK Summary of Product Characteristics." O 0

2. Canadian Pharmacists Association "e-CPS." (2006):

3. Cerner Multum, Inc. "Australian Product Information." O 0

4. "PDR Generics." Montvale, NJ: Medical Economics (1995):

Further information

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.

Some side effects may not be reported. You may report them to the FDA.