Serentil Side Effects
Generic Name: mesoridazine
Note: This document contains side effect information about mesoridazine. Some of the dosage forms listed on this page may not apply to the brand name Serentil.
Applies to mesoridazine: injectable solution, oral concentrate, oral tablet
Drugs with the potential to prolong the QTc interval have been associated with torsades de pointes-type arrhythmias and sudden death.[Ref]
Cardiovascular side effects including hypotension and tachycardia have been reported. Mesoridazine has also been reported to prolong the QTc interval in a dose related manner.[Ref]
Central nervous system side effects including drowsiness, Parkinson's syndrome, dizziness, weakness, tremor, restlessness, ataxia, dystonia, rigidity, slurring, akathisia, and motoric reactions (opisthotonos) have been reported. Autonomic nervous system effects including dry mouth, nausea and vomiting, fainting, stuffy nose, photophobia, constipation, and blurred vision have also been reported.[Ref]
Adverse effects including rigidity and motoric effects tend to occur later in therapy.[Ref]
Genitourinary side effects including inhibition of ejaculation, impotence, enuresis, incontinence and priapism have been reported.[Ref]
Dermatologic side effects including itching, rash, hypertrophic papillae of the tongue, and angioneurotic edema have been reported.[Ref]
1. "Product Information. Serentil (mesoridazine)" Boehringer-Ingelheim, Ridgefield, CT.
2. Starck LC, Talley BJ, Brannan SK "Mesoridazine use and priapism [letter]." Am J Psychiatry 151 (1994): 946
3. Compton MT, Miller AH "Priapism associated with conventional and atypical antipsychotic medications: A review." J Clin Psychiatry 62 (2001): 362-6
Some side effects of Serentil may not be reported. Always consult your doctor or healthcare specialist for medical advice. You may also report side effects to the FDA.
More about Serentil (mesoridazine)
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- Drug class: phenothiazine antipsychotics
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