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Ragweed pollen allergen extract Side Effects

For the Consumer

Applies to ragweed pollen allergen extract: sublingual tablet

Along with its needed effects, ragweed pollen allergen extract may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.

Check with your doctor immediately if any of the following side effects occur while taking ragweed pollen allergen extract:

More common
  • Itching of the ears, mouth, and tongue
  • numbness or tingling feeling around the mouth
  • swelling of the mouth
Less common
  • Difficulty swallowing
  • discomfort in the chest
  • itching skin
  • redness, swelling, or soreness of the tongue or in the mouth
Incidence not known

Some side effects of ragweed pollen allergen extract may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:

More common

For Healthcare Professionals

Applies to ragweed pollen allergen extract: sublingual tablet


The most common side effects reported were throat irritation, oral pruritus, ear pruritus, oral paresthesia, mouth edema, and tongue pruritus.[Ref]


Frequency not reported: Systemic allergic reactions (including anaphylaxis)[Ref]


Very common (10% or more): Throat irritation (up to 16.6%)
Common (1% to 10%): Oropharyngeal pain, throat tightness[Ref]


Common (1% to 10%): Chest discomfort[Ref]


Common (1% to 10%): Pruritus[Ref]


Very common (10% or more): Oral pruritus (10.9%), Oral paresthesia (10%)
Common (1% to 10%): Mouth edema, tongue pruritus, lip swelling, swollen tongue, lip pruritus, dry mouth, tongue edema, nausea, palatal edema, dysphagia[Ref]


Very common (10% or more): Ear pruritus (10.4%)[Ref]


1. "Product Information. Ragwitek (ragweed pollen allergen extract)." Merck & Company Inc, Whitehouse Station, NJ.

Some side effects of ragweed pollen allergen extract may not be reported. Always consult your doctor or healthcare specialist for medical advice. You may also report side effects to the FDA.

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