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Ragweed Pollen Allergen Extract Side Effects

Medically reviewed by Drugs.com. Last updated on Dec 12, 2024.

Applies to ragweed pollen allergen extract: sublingual tablet.

Important warnings This medicine can cause some serious health issues

Sublingual route (tablet)

Short ragweed (Ambrosia artemisiifolia) pollen extract can cause life-threatening allergic reactions such as anaphylaxis and severe laryngopharyngeal restriction.

Do not administer short ragweed pollen extract to patients with severe, unstable or uncontrolled asthma.

Observe patients in the office for at least 30 minutes following the initial dose.

Prescribe auto-injectable epinephrine, instruct and train patients or parents/guardians on its appropriate use, and instruct patients or parents/guardians to seek immediate medical care upon its use.

Short ragweed pollen extract may not be suitable for patients with certain underlying medical conditions that may reduce their ability to survive a serious allergic reaction or for patients who may be unresponsive to epinephrine or inhaled bronchodilators, such as those taking beta-blockers.

Precautions

It is very important that your doctor check your progress while you are using this medicine. This will allow your doctor to see if the medicine is working properly and to decide if you should continue to take it.

This medicine may cause serious allergic reactions, including anaphylaxis, which can be life-threatening and require immediate medical attention. Check with your doctor right away if you have cough, difficulty swallowing, dizziness, fast heartbeat, hives, itching, puffiness or swelling of the eyelids or around the eyes, face, lips, or tongue, skin rash, tightness in the chest, trouble breathing, or unusual tiredness or weakness. If these side effects occur, get emergency help at once.

Your doctor may recommend that you have an emergency injection for allergic reactions available during the time of year you take this medication. If this is the case, make sure that you know how to use it properly for yourself in case of a serious allergic reaction.

This medicine may increase risk of eosinophilic esophagitis. Check with your doctor right away if you have severe chest pain or trouble swallowing while taking this medicine.

If you have trouble breathing or if your asthma becomes difficult to control, call your doctor immediately.

Do not take other medicines unless they have been discussed with your doctor. This includes prescription or nonprescription (over-the-counter [OTC]) medicines and herbal or vitamin supplements.

Serious side effects

Along with its needed effects, ragweed pollen allergen extract may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.

Check with your doctor immediately if any of the following side effects occur while taking ragweed pollen allergen extract:

More common side effects

  • itching of the ears, mouth, and tongue
  • numbness or tingling feeling around the mouth
  • swelling or inflammation of the mouth
  • trouble breathing
  • upper stomach pain

Less common side effects

  • difficulty swallowing
  • discomfort in the chest
  • itching skin
  • redness, irritation, swelling, or soreness of the tongue or in the mouth

Incidence not known

  • cough
  • dizziness
  • fast heartbeat
  • hives or skin rash
  • large, hive-like swelling on the face, eyelids, lips, tongue, throat, hands, legs, feet, or sex organs
  • puffiness or swelling of the eyelids or around the eyes, face, lips, or tongue
  • sore throat
  • sweating
  • tightness in the chest
  • voice changes

Other side effects

Some side effects of ragweed pollen allergen extract may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects.

Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:

More common side effects

Incidence not known

For healthcare professionals

Applies to ragweed pollen allergen extract: sublingual tablet.

General adverse events

The most common side effects reported were throat irritation, oral pruritus, ear pruritus, oral paresthesia, mouth edema, and tongue pruritus.[Ref]

Hypersensitivity

Respiratory

Cardiovascular

Dermatologic

Gastrointestinal

Other

See also:

References

1. (2014) "Product Information. Ragwitek (ragweed pollen allergen extract)." Merck & Co., Inc

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Further information

Ragweed pollen allergen extract side effects can vary depending on the individual. Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.

Note: Medication side effects may be underreported. If you are experiencing side effects that are not listed, submit a report to the FDA by following this guide.