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Ragweed Pollen Allergen Extract Dosage

Medically reviewed by Drugs.com. Last updated on June 22, 2020.

Applies to the following strengths: 12 Amb a 1-U

Usual Adult Dose for Allergic Rhinitis

One tablet sublingually once a day.

Comments:
-Initiate treatment at least 12 weeks before the expected onset of each ragweed pollen season and continue treatment throughout the season.

Use: Treatment of short ragweed pollen-induced allergic rhinitis, with or without conjunctivitis, confirmed by positive skin test or in vitro testing for pollen-specific IgE antibodies for short ragweed pollen.

Renal Dose Adjustments

Data not available

Liver Dose Adjustments

Data not available

Precautions

US BOXED WARNING:
-Short ragweed allergen can cause life-threatening allergic reactions such as anaphylaxis and severe laryngopharyngeal restriction.
-Do not administer short ragweed allergen to patients with severe, unstable or uncontrolled asthma.
-Observe patients in the office for at least 30 minutes following the initial dose.
-Prescribe auto-injectable epinephrine, instruct and train patients on its appropriate use, and instruct patients to seek immediate medical care upon its use.
-May not be suitable for patients with certain underlying medical conditions that may reduce their ability to survive a serious allergic reaction.
-May not be suitable for patients who may be unresponsive to epinephrine or inhaled bronchodilators, such as those taking beta-blockers.

Safety and efficacy have not been established in patients younger than 18 years.

Consult WARNINGS section for additional precautions.

Dialysis

Data not available

Other Comments

Administration advice:
-Administer the first dose in a healthcare setting under the supervision of a physician with experience in the field.
-After receiving the first dose, observe the patient for at least 30 minutes to monitor for signs or symptoms of a severe systemic or a severe local allergic reaction.
-Allow the tablet to remain under the tongue until completely dissolved. Do not swallow for at least 1 minute.
-Wash hands after handling the tablet.
-Do not take the tablet with food or beverage. Food or beverage should not be taken for at least 5 minutes after taking the tablet.
-Prescribe auto-injectable epinephrine to patients and instruct them in the proper use of emergency self-injection of epinephrine.

Storage requirements:
-Protect from moisture

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