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Pitavastatin Side Effects

For the Consumer

Applies to pitavastatin: oral tablet

As well as its needed effects, pitavastatin may cause unwanted side effects that require medical attention.

Severity: Major

If any of the following side effects occur while taking pitavastatin, check with your doctor immediately:

Less common:
  • Difficulty with moving
  • joint pain
  • muscle aching or cramping
  • muscle pains or stiffness
  • pain in the arms and legs
  • swollen joints
Incidence not known:
  • Chills
  • cough
  • diarrhea
  • fever
  • general feeling of discomfort or illness
  • headache
  • loss of appetite
  • nausea
  • runny nose
  • shivering
  • sore throat
  • sweating
  • trouble with sleeping
  • unusual tiredness or weakness
  • vomiting

Severity: Minor

Some pitavastatin side effects may not need any medical attention. As your body gets used to the medicine these side effects may disappear. Your health care professional may be able to help you prevent or reduce these side effects, but do check with them if any of the following side effects continue, or if you are concerned about them:

Less common:
  • Back pain
  • difficulty having a bowel movement (stool)
Incidence not known:
  • Hives or welts
  • itching skin
  • rash
  • redness of the skin

For Healthcare Professionals

Applies to pitavastatin: oral tablet


Hypersensitivity side effects have included rash, pruritus, and urticaria.[Ref]


Musculoskeletal side effects have included back pain (1.4% to 3.9%), myalgia (1.9% to 3.1%), pain in extremity (0.6% to 2.3%), and arthralgia.[Ref]


Gastrointestinal side effects have included constipation (1.5% to 3.6%) and diarrhea (1.5% to 2.6%).[Ref]

Nervous system

Nervous system side effects have included headache.[Ref]


Psychiatric side effects of HMG-CoA reductase inhibitors have included decreased libido, anxiety, insomnia, depression, suicidal thoughts, delusions, paranoia, agitation, and nightmares. Psychiatric side effects reported postmarketing have included cognitive impairment (e.g., memory loss, forgetfulness, amnesia, memory impairment, confusion) associated with statin use. These cognitive issues have been reported for all statins. The reports are generally nonserious, and reversible upon statin discontinuation, with variable times to symptom onset (1 day to years) and symptom resolution (median of 3 weeks).


Other side effects reported postmarketing have included abdominal discomfort, abdominal pain, dyspepsia, nausea, asthenia, fatigue, malaise, hepatitis, jaundice, fatal and nonfatal hepatic failure, dizziness, hypoesthesia, insomnia, depression, interstitial lung disease, erectile dysfunction and muscle spasms.[Ref]


1. "Product Information. Livalo (pitavastatin)." Lilly, Eli and Company, Indianapolis, IN.

It is possible that some side effects of pitavastatin may not have been reported. These can be reported to the FDA here. Always consult a healthcare professional for medical advice.

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