Optimine Side Effects

Generic name: azatadine

Note: This document provides detailed information about Optimine Side Effects associated with azatadine. Some dosage forms listed on this page may not apply specifically to the brand name Optimine.

Applies to azatadine: oral tablet.

Stop taking azatadine (the active ingredient contained in Optimine) and seek emergency medical attention if you experience an allergic reaction (difficulty breathing; closing of your throat; swelling of your lips, tongue, or face; or hives).

Other, less serious side effects may be more likely to occur. Continue to take azatadine and talk to your doctor if you experience

• sleepiness, fatigue, or dizziness;

• headache;

• dry mouth; or

• difficulty urinating or an enlarged prostate.

Side effects other than those listed here may also occur. Talk to your doctor about any side effect that seems unusual or that is especially bothersome.

See also:

For healthcare professionals

Applies to azatadine: oral tablet.

Nervous system adverse events

Nervous system side effects have commonly included central nervous system depression with resulting drowsiness. Azatadine (the active ingredient contained in Optimine) has also caused dizziness and affected coordination.^[Ref]

The drowsiness caused by azatadine may subside in some patients following prolonged use. Patients should be warned against driving, as well as concomitant ingestion of alcohol and other sedative-hypnotic drugs, while taking azatadine.

At dosages above what is normally recommended, dystonic reactions have occurred.^[Ref]

Gastrointestinal

Gastrointestinal side effects have included dry mouth and constipation due to anticholinergic effects. Patients have also experienced epigastric distress and nausea. Increased appetite has been reported.^[Ref]

Cardiovascular

Cardiovascular side effects have included hypotension, tachycardia, and palpitations.^[Ref]

Ocular

Ocular side effects have included blurred vision, diplopia, and dry eyes due to cholinergic blockade.^[Ref]

Genitourinary

Genitourinary side effects have included dysuria, urinary hesitancy, decrease in urinary flow, and in rare cases, acute urinary retention. These urinary tract effects may have been due to azatadine (the active ingredient contained in Optimine)'s anticholinergic effects.^[Ref]

Hematologic

Hematologic side effects have included reports of bone marrow suppression, thrombocytopenia, and aplastic anemia.^[Ref]

Respiratory

Respiratory side effects have included thickening of bronchial secretions.^[Ref]

Hypersensitivity

Hypersensitivity reactions to azatadine (the active ingredient contained in Optimine) have included rash and urticaria.^[Ref]

Further information

Optimine side effects can vary depending on the individual. Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.

Note: Medication side effects may be underreported. If you are experiencing side effects that are not listed, submit a report to the FDA by following this guide.

Medical Disclaimer