Skip to main content

Olodaterol / tiotropium Side Effects

Medically reviewed by Last updated on Nov 4, 2023.

Applies to olodaterol / tiotropium: inhalation spray.

Serious side effects

Along with its needed effects, olodaterol/tiotropium may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.

Check with your doctor immediately if any of the following side effects occur while taking olodaterol / tiotropium:

More common

Less common

Other side effects

Some side effects of olodaterol / tiotropium may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects.

Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:

Less common

For Healthcare Professionals

Applies to olodaterol / tiotropium: inhalation aerosol.


The most common serious adverse reactions were COPD exacerbation and pneumonia.[Ref]


Common (1% to 10%): Nasopharyngitis, cough, epistaxis, pharyngitis, dysphonia, bronchospasm, laryngitis, sinusitis[Ref]


Common (1% to 10%): Atrial fibrillation, palpitations, supraventricular tachycardia[Ref]


Common (1% to 10%): Rash, pruritus, angioneurotic edema, urticaria, skin infection, and skin ulcer, dry skin[Ref]


Common (1% to 10%): Dry mouth, constipation, oropharyngeal candidiasis, dysphagia, gastroesophageal reflux disease, gingivitis, glossitis, stomatitis, intestinal obstruction including ileus paralytic[Ref]


Common (1% to 10%): Urinary retention, dysuria, urinary tract infection


Common (1% to 10%): Immediate hypersensitivity reactions[Ref]


Common (1% to 10%): Dehydration[Ref]


Common (1% to 10%): Back pain, arthralgia, joint swelling[Ref]

Nervous system

Common (1% to 10%): Dizziness, insomnia[Ref]


Common (1% to 10%): Glaucoma, increased intraocular pressure, blurred vision[Ref]


1. "Product Information. Stiolto Respimat 60 ACT (olodaterol-tiotropium)." Boehringer Ingelheim

Further information

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.

Some side effects may not be reported. You may report them to the FDA.