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Natrecor Side Effects

Generic name: nesiritide

Medically reviewed by Last updated on Apr 19, 2022.

Note: This document contains side effect information about nesiritide. Some of the dosage forms listed on this page may not apply to the brand name Natrecor.


Common side effects of Natrecor include: asymptomatic hypotension, hypotension, symptomatic hypotension, and increased serum creatinine. See below for a comprehensive list of adverse effects.

For the Consumer

Applies to nesiritide: parenteral powder for injection

Side effects include:

Hypotension, headache, back pain, nausea.

For Healthcare Professionals

Applies to nesiritide: intravenous powder for injection


The most frequently reported side effects were hypotension, headache, nausea, renal impairment, and back pain.[Ref]


Very common (10% or more): Hypotension (12%)[Ref]


Very common (10% or more): GFR decreased (up to 31.4%), serum creatinine increased (up to 28%)[Ref]

Nervous system

Common (1% to 10%): Headache, dizziness[Ref]


Postmarketing reports: Pruritus, rash[Ref]


Common (1% to 10%): Back pain[Ref]


Common (1% to 10%): Hypoglycemia[Ref]


Common (1% to 10%): Nausea[Ref]


Postmarketing reports: Infusion site extravasation[Ref]


Postmarketing reports: Hypersensitivity reaction[Ref]

More about Natrecor (nesiritide)

Patient resources

Professional resources

Related treatment guides


1. "Product Information. Natrecor (nesiritide)." Scios Inc (2022):

Further information

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.

Some side effects may not be reported. You may report them to the FDA.