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Natrecor Side Effects

Generic Name: nesiritide

Note: This document contains side effect information about nesiritide. Some of the dosage forms listed on this page may not apply to the brand name Natrecor.

For the Consumer

Applies to nesiritide: intravenous powder for solution

Along with its needed effects, nesiritide (the active ingredient contained in Natrecor) may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.

Check with your doctor immediately if any of the following side effects occur while taking nesiritide:

More common
  • Low blood pressure
Less common
  • Bluish lips or skin
  • chest pain, tightness, or discomfort
  • cool, clammy skin
  • difficulty in breathing or shortness of breath
  • dizziness
  • fainting
  • lightheadedness
  • fast, slow, or irregular heartbeat
  • unusual tiredness or weakness

Some side effects of nesiritide may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:

More common
  • Headache
Less common
  • Abdominal or stomach pain
  • anxiety
  • back pain
  • burning, crawling, itching, numbness, prickling, "pins and needles", or tingling feelings on the skin
  • change in vision
  • confusion
  • coughing or spitting up blood
  • fever
  • increased cough
  • itching skin
  • leg cramps
  • nausea
  • pain or irritation at the injection site
  • pale skin, unusual bleeding or bruising
  • rash
  • sleepiness or unusual drowsiness
  • sleeplessness
  • sweating
  • trembling or shakiness
  • vomiting

For Healthcare Professionals

Applies to nesiritide: intravenous powder for injection

General

The most frequently reported side effects were hypotension, headache, nausea, renal impairment, and back pain.[Ref]

Cardiovascular

Very common (10% or more): Hypotension (12%)[Ref]

Renal

Very common (10% or more): GFR decreased (up to 31.4%), serum creatinine increased (up to 28%)[Ref]

Nervous system

Common (1% to 10%): Headache, dizziness[Ref]

Dermatologic

Postmarketing reports: Pruritus, rash[Ref]

Musculoskeletal

Common (1% to 10%): Back pain[Ref]

Metabolic

Common (1% to 10%): Hypoglycemia[Ref]

Gastrointestinal

Common (1% to 10%): Nausea[Ref]

Local

Postmarketing reports: Infusion site extravasation[Ref]

Hypersensitivity

Postmarketing reports: Hypersensitivity reaction[Ref]

References

1. "Product Information. Natrecore (nesiritide)" Scios Inc, Sunnyvale, CA.

Some side effects of Natrecor may not be reported. Always consult your doctor or healthcare specialist for medical advice. You may also report side effects to the FDA.

Disclaimer: Every effort has been made to ensure that the information provided is accurate, up-to-date and complete, but no guarantee is made to that effect. In addition, the drug information contained herein may be time sensitive and should not be utilized as a reference resource beyond the date hereof. This material does not endorse drugs, diagnose patients, or recommend therapy. This information is a reference resource designed as supplement to, and not a substitute for, the expertise, skill , knowledge, and judgement of healthcare practitioners in patient care. The absence of a warning for a given drug or combination thereof in no way should be construed to indicate safety, effectiveness, or appropriateness for any given patient. Drugs.com does not assume any responsibility for any aspect of healthcare administered with the aid of materials provided. The information contained herein is not intended to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions, or adverse effects. If you have questions about the substances you are taking, check with your doctor, nurse, or pharmacist.

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