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Mulpleta Side Effects

Generic name: lusutrombopag

Medically reviewed by Last updated on Aug 10, 2023.

Note: This document contains side effect information about lusutrombopag. Some dosage forms listed on this page may not apply to the brand name Mulpleta.

Applies to lusutrombopag: oral tablet.

Serious side effects of Mulpleta

Along with its needed effects, lusutrombopag (the active ingredient contained in Mulpleta) may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.

Check with your doctor immediately if any of the following side effects occur while taking lusutrombopag:

More common

Incidence not known

Other side effects of Mulpleta

Some side effects of lusutrombopag may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects.

Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:

Less common

For Healthcare Professionals

Applies to lusutrombopag: oral tablet.


The most common adverse reaction was headache.[Ref]

Nervous system

Common (1% to 10%): Headache[Ref]


Common (1% to 10%): Portal vein thrombosis[Ref]

Frequently asked questions


1. (2018) "Product Information. Mulpleta (lusutrombopag)." Shionogi USA Inc

Further information

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.

Some side effects may not be reported. You may report them to the FDA.