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Minotal Side Effects

Generic name: acetaminophen / butalbital / caffeine

Medically reviewed by Drugs.com. Last updated on May 5, 2024.

Note: This document provides detailed information about Minotal Side Effects associated with acetaminophen / butalbital / caffeine. Some dosage forms listed on this page may not apply specifically to the brand name Minotal.

Applies to acetaminophen / butalbital / caffeine: oral capsule, oral solution, oral tablet.

Important warnings This medicine can cause some serious health issues

Oral route (capsule)

Liver failure, sometimes associated with liver transplant or fatalities, has occurred with acetaminophen use.

These cases of liver injury were often associated with the use of more than 1 acetaminophen-based product and with total daily acetaminophen doses exceeding 4000 mg.

Serious side effects of Minotal

Along with its needed effects, acetaminophen/butalbital/caffeine may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.

Check with your doctor immediately if any of the following side effects occur while taking acetaminophen / butalbital / caffeine:

More common

Incidence not known

  • abdominal or stomach pain
  • black, tarry stools
  • bleeding gums
  • blistering, peeling, or loosening of the skin
  • blood in the urine or stools
  • blurred vision
  • change in the frequency of urination or amount of urine
  • chills
  • cough
  • diarrhea
  • difficulty with breathing
  • difficulty with swallowing
  • dizziness
  • drowsiness
  • dry mouth
  • fainting
  • fast, pounding, or irregular heartbeat or pulse
  • flushed or dry skin
  • fruit-like breath odor
  • hives, itching, or skin rash
  • increased hunger
  • increased thirst
  • increased urination
  • joint or muscle pain
  • loss of appetite
  • nausea or vomiting
  • pinpoint red spots on the skin
  • puffiness or swelling of the eyelids or around the eyes, face, lips, or tongue
  • red skin lesions, often with a purple center
  • red, irritated eyes
  • seizures
  • shakiness in the legs, arms, hands, or feet
  • sore throat
  • sores, ulcers, or white spots in the mouth or on the lips
  • sweating
  • swelling of the feet or lower legs
  • tightness in the chest
  • trembling or shaking of the hands or feet
  • troubled breathing
  • unexplained weight loss
  • unusual bleeding or bruising
  • unusual tiredness or weakness
  • weakness

Get emergency help immediately if any of the following symptoms of overdose occur while taking acetaminophen / butalbital / caffeine:

Symptoms of overdose

Other side effects of Minotal

Some side effects of acetaminophen / butalbital / caffeine may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects.

Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:

More common

  • relaxed and calm
  • sleepiness

Incidence not known

  • anxiety
  • bloated
  • constipation
  • continuing ringing or buzzing or other unexplained noise in the ears
  • depression
  • earache
  • excess air or gas in the stomach or intestines
  • false or unusual sense of well-being
  • full feeling
  • hearing loss
  • heartburn
  • heavy eyelids
  • high energy
  • hot spells
  • hyperventilation
  • irritability
  • numbness
  • pain in the leg
  • passing gas
  • sluggishness
  • stuffy nose
  • tingling sensation

For healthcare professionals

Applies to acetaminophen / butalbital / caffeine: oral capsule, oral liquid, oral tablet.

General

The most frequently reported adverse events have included drowsiness, lightheadedness, dizziness, sedation, shortness of breath, nausea, vomiting, abdominal pain, and intoxicated feeling.[Ref]

Nervous system

Butalbital/Acetaminophen/Caffeine:

Caffeine:

Hepatic

Acetaminophen:

Acute liver failure has been reported with acetaminophen use; many case have been associated with use at doses in excess of 4 g/day, and often involving more than 1 acetaminophen-containing product.[Ref]

Gastrointestinal

Renal

Butalbital/Acetaminophen/Caffeine:

Caffeine:

Hypersensitivity

Acetaminophen:

Hematologic

Acetaminophen:

Dermatologic

Butalbital/Acetaminophen/Caffeine:

Acetaminophen:

Several cases of dermatologic reactions including toxic epidermal necrolysis and erythema multiforme have been reported.[Ref]

Respiratory

Cardiovascular

Butalbital/Acetaminophen/Caffeine:

Caffeine:

Other

Metabolic

Caffeine:

Musculoskeletal

Psychiatric

Butalbital/Acetaminophen/Caffeine:

Caffeine:

References

1. (2022) "Product Information. Fioricet (acetaminophen / butalbital / caffeine)." Novartis Pharmaceuticals

2. (2016) "Product Information. Acetaminophen/Butalbital/Caffeine (acetaminophen / butalbital / caffeine)." Par Pharmaceutical Inc (formerly Qualitest Pharmaceuticals Inc)

3. (2016) "Product Information. Esgic (acetaminophen / butalbital / caffeine)." Forest Pharmaceuticals

4. (2016) "Product Information. Vanatol LQ (acetaminophen / butalbital / caffeine)." GM Pharmaceuticals

Further information

Minotal side effects can vary depending on the individual. Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.

Some side effects may not be reported. You may report them to the FDA.