Jenloga Side Effects
Generic name: clonidine
Medically reviewed by Drugs.com. Last updated on Sep 18, 2024.
Note: This document provides detailed information about Jenloga Side Effects associated with clonidine. Some dosage forms listed on this page may not apply specifically to the brand name Jenloga.
Applies to clonidine: epidural solution.
Other dosage forms:
Important warnings
This medicine can cause some serious health issues
Epidural route (solution)
The 500-mcg/mL strength product should be diluted prior to use in an appropriate solution.
Epidural clonidine is not recommended for obstetrical, postpartum, or perioperative pain management.
The risk of hemodynamic instability, especially hypotension and bradycardia, from epidural clonidine may be unacceptable in these patients.
However, in a rare obstetrical, postpartum or perioperative patient, potential benefits may outweigh the possible risks.
Precautions
This medicine should not be stopped without the doctor's supervision. Serious side effects may occur if clonidine (the active ingredient contained in Jenloga) is stopped suddenly.
This medicine may add to the effects of alcohol and other CNS depressants (medicine that may make you drowsy or less alert). Check with your doctor before taking any such depressants while you are using this medicine.
Dizziness, light-headedness, or fainting may occur, especially when you get up from a lying or sitting position. Getting up slowly may help.
This medicine may cause some people to become drowsy or less alert than they are normally. Make sure you know how you react to this medicine before you drive, use machines, or do other jobs that require you to be alert.
Serious side effects of Jenloga
Along with its needed effects, clonidine may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.
Check with your doctor as soon as possible if any of the following side effects occur while taking clonidine:
More common side effects
- dizziness, light-headedness, or fainting
- slow heartbeat
Less common side effects
- chest pain
- extremely shallow or slow breathing
- fast heartbeat
- fever
- hallucinations (seeing, feeling, or hearing things that are not there)
- mental depression
- sleepiness (excessive)
- vomiting
Other side effects of Jenloga
Some side effects of clonidine may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects.
Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:
More common side effects
- anxiety
- confusion
- dry mouth
- nausea
- sleepiness
Less common side effects
- constipation
- ringing, buzzing, or other unexplained noises in the ears
- sweating, unusual
- weakness
After you stop using this medicine, it may still produce some side effects that need attention. During this period of time, Check with your doctor immediately if you notice the following side effects:
- agitation
- headache
- nervousness
- pounding heartbeat
- shaking or trembling
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For healthcare professionals
Applies to clonidine: compounding powder, injectable solution, oral suspension extended release, oral tablet, oral tablet extended release, transdermal film extended release.
General adverse events
Most adverse effects are mild and diminish with continued therapy. The most frequent (which appear to be dose-related) are dry mouth (40%), drowsiness (33%), dizziness (16%), constipation (10%), and sedation (10%).[Ref]
Dermatologic
- Very common (10% or more): Contact dermatitis with the patch formulation (19%)
- Common (1% to 10%): Sweating
- Uncommon (0.1% to 1%): Pruritus, rash (localized or generalized), urticaria, erythema
- Rare (0.01% to 0.1%): Alopecia, excoriation, burning
- Very rare (less than 0.01%): Papules, throbbing, blanching, generalized macular rash, facial/tongue angioedema
- Frequency not reported: Hives, localized hypo or hyper pigmentation[Ref]
Endocrine
- Rare (0.01% to 0.1%): Gynecomastia[Ref]
Gastrointestinal
- Very common (10% or more): Dry mouth (40%), upper abdominal pain (15%), nausea (13%), vomiting (10%)
- Common (1% to 10%): Constipation, parotid gland pain
- Uncommon (0.1% to 1%): Colonic pseudo-obstruction
- Very rare (less than 0.01%): Parotitis[Ref]
Genitourinary
- Common (1% to 10%): Erectile dysfunction
- Frequency not reported: Micturition difficulty, loss of libido, decreased sexual activity, nocturia, urinary retention[Ref]
Cardiovascular
- Very common (10% or more): Hypotension (45%), orthostatic hypotension (32%)
- Common (1% to 10%): Chest pain, tachycardia
- Uncommon (0.1% to 1%): Sinus bradycardia, Raynaud's phenomenon, palpitations
- Rare (0.01% to 0.1%): Atrioventricular block, palpitations, bradycardia, syncope, congestive heart failure, electrocardiographic abnormalities (i.e., sinus node arrest, high degree AV block), cerebrovascular accident
- Frequency not reported: Bradyarrhythmia, hypertension, rebound hypertension[Ref]
Hematologic
- Rare (0.01% to 0.1%): Peripheral blood flow disturbance, thrombocytopenia[Ref]
Hepatic
- Frequency not reported: Mild transient abnormalities of liver function tests, hepatitis[Ref]
Metabolic
- Rare (0.01% to 0.1%): Blood glucose increased, serum creatine phosphokinase increased
- Frequency not reported: Weight gain, anorexia[Ref]
Musculoskeletal
- Frequency not reported: Muscle pain, joint pain, leg cramps[Ref]
Nervous system
- Very common (10% or more): Drowsiness (33%), dizziness (16%), somnolence (13%), sedation (10%)
- Common (1% to 10%): Headache
- Uncommon (0.1% to 1%): Paresthesia
- Frequency not reported: Headache, localized numbness[Ref]
Ocular
- Rare (0.01% to 0.1%): Lacrimation decreased (dry eyes)
- Frequency not reported: Accommodation disorder, ocular burning, vision blurred[Ref]
Other
- Common (1% to 10%): Fatigue, tinnitus
- Uncommon (0.1% to 1%): Malaise
- Frequency not reported: Fever, pallor, weakness, positive Coombs' test, increased sensitivity to alcohol[Ref]
Psychiatric
- Very common (10% or more): Confusion (13%)
- Common (1% to 10%): Depression, tearfulness, sleep disorder, hallucinations (both visual and auditory), nervousness, agitation
Uncommon (0.1% to 1%):
- Rare (0.01% to 0.1%): Delusional perception, nightmare
- Frequency not reported: Libido decreased, restlessness, anxiety, irritability, behavior changes[Ref]
Respiratory
- Common (1% to 10%): Hypoventilation
- Rare (0.01% to 0.1%): Nasal dryness[Ref]
References
1. Cerner Multum, Inc. "UK Summary of Product Characteristics."
2. Cerner Multum, Inc. "Australian Product Information."
3. (2016) "Product Information. CloNIDine Hydrochloride (clonidine)." Unichem Pharmaceuticals Inc
More about Jenloga (clonidine)
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- Imprints, shape & color data
- Dosage information
- During pregnancy
- Drug class: antiadrenergic agents, centrally acting
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Further information
Jenloga side effects can vary depending on the individual. Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.
Note: Medication side effects may be underreported. If you are experiencing side effects that are not listed, submit a report to the FDA by following this guide.