Ibrexafungerp Side Effects

Medically reviewed by Drugs.com. Last updated on Aug 7, 2024.

Applies to ibrexafungerp: oral tablet.

Important warnings This medicine can cause some serious health issues

Oral route (tablet)

Warning: Risk of Embryo-Fetal Toxicity. Ibrexafungerp is contraindicated in pregnancy because it may cause fetal harm based on findings from animal reproductive studies.For females of reproductive potential, verify that the patient is not pregnant prior to initiating ibrexafungerp treatment.

Reassessing pregnancy status prior to each dose is recommended when ibrexafungerp is used monthly for 6 months for reduction in the incidence of recurrent vulvovaginal candidiasis (RVVC).Advise females of reproductive potential to use effective contraception during treatment of vulvovaginal candidiasis (VVC) and throughout the 6-month treatment period for reduction in the incidence of RVVC with ibrexafungerp and, for 4 days after the last dose.

Common side effects of ibrexafungerp

Some side effects of ibrexafungerp may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects.

Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:

More common

• diarrhea
• nausea
• stomach pain

Less common

• back pain
• bloated
• dizziness
• excess air or gas in the stomach or intestines
• full feeling
• passing gas
• vomiting

Serious side effects of ibrexafungerp

Along with its needed effects, ibrexafungerp may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.

Check with your doctor immediately if any of the following side effects occur while taking ibrexafungerp:

Less common

• difficulty in breathing or swallowing
• fast heartbeat
• lower stomach pain or cramps
• skin itching, rash, or redness
• swelling of the face, throat, or tongue
• vaginal bleeding

For healthcare professionals

Applies to ibrexafungerp: oral tablet.

Dermatologic

• Frequency not reported: Rash

Gastrointestinal

• Very common (10% or more): Diarrhea (up to 16.7%), nausea (up to 11.9%), abdominal pain (up to 11.4%)
• Common (1% to 10%): Vomiting
• Frequency not reported: Flatulence

Abdominal pain included abdominal pain, upper abdominal pain, lower abdominal pain, and abdominal discomfort.

Genitourinary

• Common (1% to 10%): Urinary tract infection
• Frequency not reported: Dysmenorrhea, vaginal bleeding

Hepatic

• Frequency not reported: Elevated transaminases

Hypersensitivity

• Frequency not reported: Hypersensitivity reaction

Musculoskeletal

• Frequency not reported: Back pain

Nervous system

• Very common (10% or more): Headache (up to 17.6%)
• Common (1% to 10%): Dizziness

Dizziness included dizziness and postural dizziness.

Other

• Common (1% to 10%): Fatigue

Further information

Ibrexafungerp side effects can vary depending on the individual. Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.

Some side effects may not be reported. You may report them to the FDA.

Medical Disclaimer