Herron Paracetamol Capseals Side Effects
Generic name: acetaminophen
Medically reviewed by Drugs.com. Last updated on Feb 17, 2025.
Note: This document provides detailed information about Herron Paracetamol Capseals Side Effects associated with acetaminophen. Some dosage forms listed on this page may not apply specifically to the brand name Herron Paracetamol Capseals.
Applies to acetaminophen: capsule, capsule liquid filled, elixir, liquid, powder, solution, suppository, suspension, tablet, tablet chewable, tablet disintegrating, tablet extended release.
Other dosage forms:
Precautions
It is very important that your doctor check the progress of you or your child while you are using this medicine. This will allow your doctor to see if the medicine is working properly and to decide if you should continue to take it.
If your symptoms or fever do not improve within a few days or if they become worse, check with your doctor.
Many combination medicines contain acetaminophen (the active ingredient contained in Herron Paracetamol Capseals), including products with brand names such as Alka-Seltzer Plus®, Comtrex®, Drixoral®, Excedrin Migraine®, Midol®, Sinutab®, Sudafed®, Theraflu®, and Vanquish®. Adding these medicines to the medicine you already take may cause you to get more than a safe amount of acetaminophen. Talk to your doctor before taking more than one medicine that contains acetaminophen.
Check with your doctor right away if you or your child have pain or tenderness in the upper stomach; pale stools; dark urine; loss of appetite; nausea; unusual tiredness or weakness; or yellow eyes or skin. These could be symptoms of a serious liver problem.
If you will be taking more than an occasional 1 or 2 doses of acetaminophen, do not drink alcoholic beverages. To do so may increase the chance of liver damage, especially if you drink large amounts of alcohol on a regular basis, if you take more acetaminophen than is recommended on the label, or if you take it regularly for a long time.
Acetaminophen may interfere with the results of some medical tests. Before you have any medical tests, tell the person in charge if you have taken acetaminophen within the past 3 or 4 days. You may also call the laboratory ahead of time to find out whether acetaminophen will cause a problem.
Acetaminophen may cause false results with some blood glucose tests. If you are diabetic and notice a change in your test results, or if you have any questions, check with your doctor.
If you think you have taken too much acetaminophen, get emergency help at once, even if there are no signs of poisoning. Treatment to prevent liver damage must be started as soon as possible.
Serious side effects
Along with its needed effects, acetaminophen may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.
Check with your doctor immediately if any of the following side effects occur while taking acetaminophen:
Rare side effects
- bloody or black, tarry stools
- bloody or cloudy urine
- fever with or without chills (not present before treatment and not caused by the condition being treated)
- pain in the lower back and/or side (severe and/or sharp)
- pinpoint red spots on the skin
- skin rash, hives, or itching
- sore throat (not present before treatment and not caused by the condition being treated)
- sores, ulcers, or white spots on the lips or in the mouth
- sudden decrease in the amount of urine
- unusual bleeding or bruising
- unusual tiredness or weakness
- yellow eyes or skin
Get emergency help immediately if any of the following symptoms of overdose occur while taking acetaminophen:
Symptoms of overdose
- diarrhea
- increased sweating
- loss of appetite
- nausea or vomiting
- stomach cramps or pain
- swelling, pain, or tenderness in the upper abdomen or stomach area
See also:
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For healthcare professionals
Applies to acetaminophen: compounding powder, intravenous solution, oral capsule, oral granule effervescent, oral liquid, oral powder, oral powder for reconstitution, oral suspension, oral tablet, oral tablet chewable, oral tablet disintegrating, oral tablet extended release, rectal suppository.
General adverse events
In general, acetaminophen (the active ingredient contained in Herron Paracetamol Capseals) is well-tolerated when administered in therapeutic doses. The most commonly reported adverse reactions have included nausea, vomiting, constipation. Injection site pain and injection site reaction have been reported with the IV product.[Ref]
Hepatic
- Common (1% to 10%): Increased aspartate aminotransferase
- Rare (less than 0.1%): Increased hepatic transaminases
- Frequency not reported: Liver failure[Ref]
Gastrointestinal
- Very common (10% or more): Nausea (up to 34%), Vomiting (up to 15%)
- Common (1% to 10%): Abdominal pain, diarrhea, constipation, dyspepsia, enlarged abdomen
- Frequency not reported: Dry mouth[Ref]
Hypersensitivity
- Postmarketing reports: Anaphylaxis, hypersensitivity reactions[Ref]
Hematologic
- Common (1% to 10%): Anemia, postoperative hemorrhage
- Very rare (less than 0.01%): Thrombocytopenia, leucopenia, neutropenia[Ref]
Dermatologic
- Common (1% to 10%): Rash, pruritus
- Rare (less than 0.1%): Serious skin reactions such as acute generalized exanthematous pustulosis, Stevens-Johnson syndrome, and toxic epidermal necrolysis
- Very rare (less than 0.01%): Pemphigoid reaction, pustular rash, Lyell syndrome[Ref]
Respiratory
- Common (1% to 10%): Dyspnea, abnormal breath sounds, pulmonary edema, hypoxia, pleural effusion, stridor, wheezing, coughing[Ref]
Cardiovascular
- Common (1% to 10%): Peripheral edema, hypertension, hypotension, tachycardia, chest pain[Ref]
Metabolic
- Common (1% to 10%): Hypokalemia, hyperglycemia[Ref]
Nervous system
- Common (1% to 10%): Headache, dizziness
- Frequency not reported: Dystonia
Musculoskeletal
- Common (1% to 10%): Muscle spasms, trismus
Psychiatric
- Common (1% to 10%): Insomnia, anxiety
Genitourinary
- Common (1% to 10%): Oliguria
Local
- Common (1% to 10%): Infusion site pain, injection site reactions
Ocular
- Common (1% to 10%): Periorbital edema
Other
- Common (1% to 10%): Pyrexia, fatigue
- Rare (0.01% to 0.1%): Malaise
References
1. "Multum Information Services, Inc. Expert Review Panel"
2. Zimmerman HJ, Maddrey WC (1995) "Acetaminophen (paracetamol) hepatotoxicity with regular intake of alcohol: analysis of instances of therapeutic misadventure." Hepatology, 22, p. 767-73
3. Gursoy M, Haznedaroglu IC, Celik I, Sayinalp N, Ozcebe OI, Dundar SV (1996) "Agranulocytosis, plasmacytosis, and thrombocytosis followed by a leukemoid reaction due to acute acetaminophen toxicity." Ann Pharmacother, 30, p. 762-5
4. Kurtovic J, Riordan SM (2003) "Paracetamol-induced hepatotoxicity at recommended dosage." J Intern Med, 253, p. 240-3
5. Vitols S (2003) "Paracetamol hepatotoxicity at therapeutic doses." J Intern Med, 253, p. 95-8
6. Kaysen GA, Pond SM, Roper MH, Menke DJ, Marrama MA (1985) "Combined hepatic and renal injury in alcoholics during therapeutic use of acetaminophen." Arch Intern Med, 145, p. 2019-23
7. O'Dell JR, Zetterman RK, Burnett DA (1986) "Centrilobular hepatic fibrosis following acetaminophen-induced hepatic necrosis in an alcoholic." JAMA, 255, p. 2636-7
8. Seeff LB, Cuccherini BA, Zimmerman HJ, Adler E, Benjamin SB (1986) "Acetaminophen hepatotoxicity in alcoholics." Ann Intern Med, 104, p. 399-404
9. Minton NA, Henry JA, Frankel RJ (1988) "Fatal paracetamol poisoning in an epileptic." Hum Toxicol, 7, p. 33-4
10. Keaton MR (1988) "Acute renal failure in an alcoholic during therapeutic acetaminophen ingestion." South Med J, 81, p. 1163-6
11. Shriner K, Goetz MB (1992) "Severe hepatotoxicity in a patient receiving both acetaminophen and zidovudine." Am J Med, 93, p. 94-6
12. Keays R, Harrison PM, Wendon JA, et al. (1991) "Intravenous acetylcysteine in paracetamol induced fulminant hepatic failure: a prospective controlled trial." BMJ, 303, p. 1026-9
13. Rumore MM, Blaiklock RG (1992) "Influence of age-dependent pharmacokinetics and metabolism on acetaminophen hepatotoxicity." J Pharm Sci, 81, p. 203-7
14. Mofenson HC, Caraccio TR, Nawaz H, Steckler G (1991) "Acetaminophen induced pancreatitis." Clin Toxicol, 29, p. 223-30
15. Kumar S, Rex DK (1991) "Failure of physicians to recognize acetaminophen hepatotoxicity in chronic alcoholics." Arch Intern Med, 151, p. 1189-91
16. Block R, Jankowski JA, Lacoux P, Pennington CR (1992) "Does hypothermia protect against the development of hepatitis in paracetamol overdose?" Anaesthesia, 47, p. 789-91
17. Brotodihardjo AE, Batey RG, Farrell GC, Byth K (1992) "Hepatotoxicity from paracetamol self-poisoning in Western Sydney: a continuing challenge." Med J Aust, 157, p. 382-5
18. Johnson GK, Tolman KG (1977) "Chronic liver disease and acetaminophen." Ann Intern Med, 87, p. 302-4
19. McJunkin B, Barwick KW, Little WC, Winfield JB (1976) "Fatal massive hepatic necrosis following acetaminophen overdose." JAMA, 236, p. 1874-5
20. Block R (1993) "Liver failure induced by paracetamol." BMJ, 306, p. 457
21. Wong V, Daly M, Boon A, Heatley V (1993) "Paracetamol and acute biliary pain with cholestasis." Lancet, 342, p. 869
22. Bray GP (1993) "Liver failure induced by paracetamol." BMJ, 306, p. 157-8
23. Lee WM (1994) "Acute liver failure." Am J Med, 96, p. 3-9
24. Bonkovsky HL, Kane RE, Jones DP, Galinsky RE, Banner B (1994) "Acute hepatic and renal toxicity from low doses of acetaminophen in the absence of alcohol abuse or malnutrition - evidence for increased susceptibility to drug toxicity due to cardiopulmonary and renal insufficiency." Hepatology, 19, p. 1141-8
25. Cheung L, Potts RG, Meyer KC (1994) "Acetaminophen treatment nomogram." N Engl J Med, 330, p. 1907-8
26. Hartleb M (1994) "Do thyroid hormones promote hepatotoxicity to acetaminophen?" Am J Gastroenterol, 89, p. 1269-70
27. Smilkstein MJ, Douglas Dr, Daya MR (1994) "Acetaminophen poisoning and liver function." N Engl J Med, 331, p. 1310-1
28. Whitcomb DC (1994) "Acetaminophen poisoning and liver function." N Engl J Med, 331, p. 1311
29. Cheung L, Meyer KC (1994) "Acetaminophen poisoning and liver function." N Engl J Med, 331, p. 1311-2
30. Whitcomb DC, Block GD (1994) "Association of acetaminopphen hepatotoxicity with fasting and ethanol use." JAMA, 272, p. 1845-50
31. Bonkovsky HL (1995) "Acetaminophen hepatotoxicity, fasting, and ethanol." JAMA, 274, p. 301
32. Nelson EB, Temple AR (1995) "Acetaminophen hepatotoxicity, fasting, and ethanol." JAMA, 274, p. 301
33. Singer AJ, Carracio TR, Mofenson HC (1995) "The temporal profile of increased transaminase levels in patients with acetaminophen-induced liver dysfunction." Ann Emerg Med, 26, p. 49-53
34. Lee WM (1995) "Medical progress: drug-induced hepatotoxicity." N Engl J Med, 333, p. 1118-27
35. Settipane RA, Stevenson DD (1989) "Cross sensitivity with acetaminophen in aspirin-sensitive subjects with asthma." J Allergy Clin Immunol, 84, p. 26-33
36. Van Diem L, Grilliat JP (1990) "Anaphylactic shock induced by paracetamol." Eur J Clin Pharmacol, 38, p. 389-90
37. Leung R, Plomley R, Czarny D (1992) "Paracetamol anaphylaxis." Clin Exp Allergy, 22, p. 831-3
38. Doan T, Greenberger PA (1993) "Nearly fatal episodes of hypotension, flushing, and dyspnea in a 47- year-old woman." Ann Allergy, 70, p. 439-44
39. Kalyoncu AF (1994) "Acetaminophen hypersensitivity and other analgesics." Ann Allergy, 72, p. 285
40. Doan T (1994) "Acetaminophen hypersensitivity and other analgesics - response." Ann Allergy, 72, p. 285
41. Kawada A, Hiruma M, Noguchi H, Ishibashi A (1996) "Fixed drug eruption induced by acetaminophen in a 12-year-old girl." Int J Dermatol, 35, p. 148-9
42. Halevi A, BenAmitai D, Garty BZ (2000) "Toxic epidermal necrolysis associated with acetaminophen ingestion." Ann Pharmacother, 34, p. 32-4
43. Shoenfeld Y, Shaklai M, Livni E, Pinkhas J (1980) "Thrombocytopenia from acetaminophen." N Engl J Med, 303, p. 47
44. Bougie DW, Benito AI, Sanchez-Abarca LI, Torres R, Birenbaum J, Aster RH (2007) "Acute thrombocytopenia caused by sensitivity to the glucuronide conjugate of acetaminophen." Blood, 109, p. 3608-9
45. Thomas RH, Munro DD (1986) "Fixed drug eruption due to paracetamol." Br J Dermatol, 115, p. 357-9
46. Guccione JL, Zemtsov A, Cobos E, Neldner KH (1993) "Acquired purpura fulminans induced by alcohol and acetaminophen - successful treatment with heparin and vitamin-k." Arch Dermatol, 129, p. 1267-9
47. Filipe PL, Freitas JP, Decastro JC, Silva R (1995) "Drug eruption induced by acetaminophen in infectious mononucleosis." Int J Dermatol, 34, p. 220-1
48. Kondo K, Inoue Y, Hamada H, Yokoyama A, Kohno N, Hiwada K (1993) "Acetaminophen-induced eosinophilic pneumonia." Chest, 104, p. 291-2
49. Brown G (1996) "Acetaminophen-induced hypotension." Heart Lung, 25, p. 137-40
50. Koulouris Z, Tierney MG, Jones G (1999) "Metabolic acidosis and coma following a severe acetaminophen overdose." Ann Pharmacother, 33, p. 1191-4
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Further information
Herron Paracetamol Capseals side effects can vary depending on the individual. Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.
Note: Medication side effects may be underreported. If you are experiencing side effects that are not listed, submit a report to the FDA by following this guide.