Ferric Pyrophosphate Side Effects

Medically reviewed by Drugs.com. Last updated on Mar 11, 2025.

Applies to ferric pyrophosphate: route not applicable powder for solution, route not applicable solution.

Precautions

It is very important that your doctor check your progress at regular visits to make sure this medicine is working properly and to check for unwanted effects.

This medicine may cause serious allergic reactions, including anaphylaxis. Anaphylaxis requires immediate medical attention. Tell your doctor right away if you have a rash, itching, lightheadedness, dizziness, fainting, trouble breathing, trouble swallowing, or any swelling of your hands, face, or mouth while you are receiving this medicine.

Using this medicine while you are pregnant can harm your unborn baby. Use an effective form of birth control to keep from getting pregnant during therapy and for at least 2 weeks after the last dose. If you think you have become pregnant while using the medicine, tell your doctor right away.

Serious side effects

Along with its needed effects, ferric pyrophosphate may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.

Check with your doctor or nurse immediately if any of the following side effects occur while taking ferric pyrophosphate:

Other side effects

Some side effects of ferric pyrophosphate may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects.

Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:

Other side effects

Some side effects of ferric pyrophosphate may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects.

Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:

For healthcare professionals

Applies to ferric pyrophosphate: parenteral powder for injection, parenteral solution.

Cardiovascular adverse events

• Very common (10% or more): Procedural hypotension (21.6%)
• Common (1% to 10%): Arteriovenous fistula thrombosis, arteriovenous fistula sight hemorrhage
• Frequency not reported: Intradialytic hypotension^[Ref]

Nervous system

• Common (1% to 10%): Headache
• Frequency not reported: Dizziness^[Ref]

Other

• Common (1% to 10%): Peripheral edema, pyrexia, asthenia, fatigue^[Ref]

Hypersensitivity

• Uncommon (0.1% to 1%): Hypersensitivity^[Ref]

Respiratory

• Common (1% to 10%): Dyspnea^[Ref]

Immunologic

• Common (1% to 10%): Urinary tract infection^[Ref]

Gastrointestinal

• Frequency not reported: Constipation, nausea^[Ref]

Dermatologic

• Frequency not reported: Pruritus^[Ref]

Musculoskeletal

• Common (1% to 10%): Muscle spasms, pain in extremity, back pain^[Ref]

See also:

Further information

Ferric pyrophosphate side effects can vary depending on the individual. Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.

Note: Medication side effects may be underreported. If you are experiencing side effects that are not listed, submit a report to the FDA by following this guide.

Medical Disclaimer