Exxua Side Effects

Generic name: gepirone

Medically reviewed by Drugs.com. Last updated on Apr 10, 2025.

Note: This document provides detailed information about Exxua Side Effects associated with gepirone. Some dosage forms listed on this page may not apply specifically to the brand name Exxua.

Applies to gepirone: oral tablet extended release.

Get emergency medical help if you have signs of an allergic reaction: hives, difficult breathing, swelling of your face, lips, tongue, or throat.

People with depression or mental illness may have thoughts about suicide. Some young people may have increased suicidal thoughts when first starting a medicine to treat depression. Stay alert to changes in your mood or symptoms. Your family or caregivers should also watch for sudden changes in your behavior.

Seek medical attention right away if you have symptoms of serotonin syndrome, such as: agitation, hallucinations, fever, sweating, shivering, fast heart rate, muscle stiffness, twitching, loss of coordination, nausea, vomiting, or diarrhea.

Call your doctor at once if you have:

• serotonin syndrome--agitation, hallucinations, fever, fast heart rate, muscle stiffness, twitching, loss of coordination, nausea, diarrhea;

• manic episodes--racing thoughts, increased energy, decreased need for sleep, risk-taking behavior, being agitated or talkative; or

• irregular heartbeats, dizziness, a light-headed feeling, like you might pass out.

Common side effects may include:

• dizziness;

• headache;

• trouble sleeping; or

• nausea, stomach pain, upset stomach.

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects.

For healthcare professionals

Applies to gepirone: oral tablet extended release.

General adverse events

The most common adverse reactions occurring in 5% of patients or more included dizziness, nausea, insomnia, abdominal pain, and dyspepsia. The most common reactions leading to treatment discontinuation included dizziness and nausea.^[Ref]

Cardiovascular

• Common (1% to 10%): Increased heart rate, palpitations

Dermatologic

• Common (1% to 10%): Hyperhidrosis

Gastrointestinal

• Very common (10% or more): Nausea (35%), diarrhea (10%)
• Common (1% to 10%): Abdominal pain, constipation, dry mouth, dyspepsia, increased appetite, vomiting

Abdominal pain included abdominal discomfort, abdominal pain, and upper abdominal pain.

Hypersensitivity

• Frequency not reported: Hypersensitivity reactions including rash, pruritus, and urticaria

Metabolic

• Common (1% to 10%): Weight increased, peripheral edema (less than 2%)

Other

• Common (1% to 10%): Feeling jittery, breast tenderness (less than 2%), increased energy (less than 2%)

Psychiatric

• Very common (10% or more): Insomnia (14%)
• Common (1% to 10%): Agitation, confusional state (less than 2%), feeling abnormal (less than 2%), poor quality sleep (less than 2%)

Insomnia included initial insomnia, insomnia, middle insomnia, and terminal insomnia.

Respiratory

• Common (1% to 10%): Nasal congestion, nasopharyngitis, upper respiratory tract infection, dyspnea (less than 2%)

Nervous system

• Very common (10% or more): Dizziness (49%), headache (31%), feeling sleepy or tired (15%),
• Common (1% to 10%): Lethargy, paresthesia, abnormal thinking (less than 2%), hypoesthesia (less than 2%)

Dizziness included lightheadedness, dizziness, and postural dizziness.

Headache included sinus headache, tension headache, and headache.

Feeling sleepy or tired included fatigue, sedation, and somnolence.

See also:

Further information

Exxua side effects can vary depending on the individual. Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.

Note: Medication side effects may be underreported. If you are experiencing side effects that are not listed, submit a report to the FDA by following this guide.

Medical Disclaimer