Emla Side Effects
Generic Name: lidocaine / prilocaine topical
Medically reviewed by Drugs.com. Last updated on Oct 8, 2020.
Note: This document contains side effect information about lidocaine / prilocaine topical. Some of the dosage forms listed on this page may not apply to the brand name Emla.
For the Consumer
Applies to lidocaine/prilocaine topical: topical application cream
Other dosage forms:
Side effects requiring immediate medical attention
Along with its needed effects, lidocaine/prilocaine topical may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.
Check with your doctor immediately if any of the following side effects occur while taking lidocaine/prilocaine topical:
- difficulty with swallowing
- large, hive-like swellings on the eyelids, face, lips, tongue, or genitals
- severe dizziness or feeling faint
- skin rash, itching, or hives
- stuffy nose
- tightness in the chest
- troubled breathing
Incidence not known
- Blisters on the skin at application site
- blue or blue-purple color of lips, fingernails, mouth, or skin
- blurred or double vision
- dark urine
- dizziness or drowsiness
- feeling hot, cold, or numb
- irregular or fast heartbeat
- muscle twitching or trembling
- ringing or buzzing in the ears
- unusual excitement, nervousness, or restlessness
- unusual tiredness or weakness
Side effects not requiring immediate medical attention
Some side effects of lidocaine / prilocaine topical may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects.
Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:
- Burning, swelling, itching, or skin rash at application site
- white or red skin at the application site
For Healthcare Professionals
Applies to lidocaine / prilocaine topical: mucous membrane gel, topical cream, topical film, topical kit
Local side effects have included erythema, edema, and abnormal sensation. Local effects observed in the trials of the cream on intact skin have included paleness (37%), erythema (30%), alterations in temperature sensations (7%), edema (6%), itching (2%), and rash (<1%). The most commonly reported local side effects in clinical studies on genital mucous membranes were redness (21%), burning sensation (17%), and edema (10%).[Ref]
1. "Product Information. Emla Cream (lidocaine-prilocaine)" Astra-Zeneca Pharmaceuticals, Wayne, PA.
More about Emla (lidocaine / prilocaine topical)
- During Pregnancy
- Dosage Information
- Drug Interactions
- En Español
- 14 Reviews
- Generic Availability
- Drug class: topical anesthetics
Related treatment guides
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.
Some side effects may not be reported. You may report them to the FDA.