Cloxapen Side Effects
Generic name: cloxacillin
Medically reviewed by Drugs.com. Last updated on Oct 18, 2022.
Note: This document contains side effect information about cloxacillin. Some dosage forms listed on this page may not apply to the brand name Cloxapen.
Applies to cloxacillin: oral capsule, oral powder for reconstitution.
Common gastrointestinal complaints include nausea, vomiting, and diarrhea. Rarely the use of cloxacillin (the active ingredient contained in Cloxapen) has been associated with pseudomembranous colitis.[Ref]
Hematologic adverse effects include neutropenia, leukopenia, and thrombocytopenia. Neutropenia has occurred in 17% of patients and occurs most commonly with higher doses and longer durations of therapy. Neutropenia occurs most often after 14 days of therapy and is reversible upon discontinuation.[Ref]
Hepatic side effects include transient increases in serum transaminases and the development of cholestatic hepatitis. Liver transaminases may take several weeks to return to normal following discontinuation of therapy. Frequent monitoring of liver function tests is recommended in patients with liver disease.[Ref]
More about Cloxapen (cloxacillin)
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- During pregnancy
- Drug class: penicillinase resistant penicillins
Related treatment guides
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Some side effects may not be reported. You may report them to the FDA.