Clioquinol / Hydrocortisone Topical Side Effects

Medically reviewed by Drugs.com. Last updated on May 29, 2024.

Applies to clioquinol/hydrocortisone topical: topical cream.

Precautions

It is very important that your doctor check the progress of you or your child at regular visits for any unwanted effects that may be caused by this medicine.

If your or your child's symptoms do not improve within 1 to 2 weeks, or if they becomes worse, check with your doctor.

This medicine may stain clothing, skin, hair, and nails yellow. Avoid getting this medicine on your clothing. Bleaching may not remove the stain.

Using too much of this medicine or using it for a long time may increase your risk of having adrenal gland problems. The risk is greater for children and patients who use large amounts for a long time. Talk to your doctor right away if you or your child have more than one of these symptoms while you are using this medicine: blurred vision, dizziness or fainting, a fast, irregular, or pounding heartbeat, increased thirst or urination, irritability, or unusual tiredness or weakness.

This medicine may make your skin more sensitive to sunlight. Use a sunscreen when you are outdoors. Avoid sunlamps and tanning beds.

Avoid using tight-fitting diapers or plastic pants on a child if this medicine is being used on the child's diaper area. Plastic pants and tight-fitting diapers may increase the chance of absorption of the medicine through the skin and the chance of side effects.

Do not use cosmetics or other skin care products on the treated skin areas.

Serious side effects

Along with its needed effects, clioquinol/hydrocortisone topical may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.

Check with your doctor immediately if any of the following side effects occur while taking clioquinol / hydrocortisone topical:

Other side effects

Some side effects of clioquinol / hydrocortisone topical may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects.

Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:

For healthcare professionals

Applies to clioquinol / hydrocortisone topical: topical cream, topical kit, topical ointment.

General adverse events

There have been a few reports of rash, hypersensitivity, and thinning of the skin following use of this combination product.^[Ref]

Local

Topical corticosteroids:

• Frequency not reported: Burning, itching, irritation, dryness, folliculitis, blistering, peeling, redness, swelling, hypertrichosis, acneiform eruptions, hypopigmentation, perioral dermatitis, allergic contact dermatitis, maceration of the skin, secondary infection, skin atrophy, striae, miliaria, irritation^[Ref]

Dermatologic

• Frequency not reported: Rash, bruising, skin thinning
• Postmarketing reports: Erythema, urticaria, skin pain, skin exfoliation, underlying symptoms exacerbated, hair discolored^[Ref]

Endocrine

• Postmarketing reports: Hypothalamic-pituitary adrenal (HPA) axis suppression, cushingoid features, endogenous cortisol levels decreased, steroid withdrawal syndrome^[Ref]

Hypersensitivity

• Frequency not reported: Hypersensitivity^[Ref]

Genitourinary

• Frequency not reported: Glucosuria

Hematologic

• Frequency not reported: Bruising

Ocular

• Postmarketing reports: Cataract, glaucoma^[Ref]

Musculoskeletal

• Postmarketing reports: Growth retardation/weight gain delayed in children, osteoporosis^[Ref]

Metabolic

• Postmarketing reports: Obesity/weight increased, hyperglycemia^[Ref]

Cardiovascular

• Postmarketing reports: Hypertension^[Ref]

See also:

Further information

Clioquinol/hydrocortisone topical side effects can vary depending on the individual. Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.

Note: Medication side effects may be underreported. If you are experiencing side effects that are not listed, submit a report to the FDA by following this guide.

Medical Disclaimer