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Bonjesta Side Effects

Generic name: doxylamine / pyridoxine

Medically reviewed by Drugs.com. Last updated on Feb 20, 2024.

Note: This document provides detailed information about Bonjesta Side Effects associated with doxylamine / pyridoxine. Some dosage forms listed on this page may not apply specifically to the brand name Bonjesta.

Applies to doxylamine / pyridoxine: oral tablet delayed release, oral tablet extended release.

Common side effects of Bonjesta

Some side effects of doxylamine / pyridoxine may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects.

Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:

More common side effects

  • unusual drowsiness

Incidence not known

  • anxiety
  • burning, crawling, itching, numbness, prickling, "pins and needles", or tingling feelings
  • confusion about identity, place, and time
  • constipation
  • diarrhea
  • dizziness or lightheadedness
  • feeling of constant movement of self or surroundings
  • general feeling of discomfort or illness
  • headache
  • increased sweating
  • irritability
  • nightmares
  • sensation of spinning
  • trouble sleeping
  • unusual tiredness or weakness

Serious side effects of Bonjesta

Along with its needed effects, doxylamine/pyridoxine may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.

Check with your doctor immediately if any of the following side effects occur while taking doxylamine / pyridoxine:

Incidence not known

  • blurred or loss of vision
  • burning feeling while urinating
  • chest discomfort or tightness
  • decrease in the frequency of urination
  • decrease in urine volume
  • difficult or labored breathing
  • difficult or painful urination
  • disturbed color perception
  • double vision
  • fast, irregular, pounding, or racing heartbeat or pulse
  • fever
  • halos around lights
  • headache, severe and throbbing
  • hives, itching, skin rash
  • hoarseness
  • irritation
  • joint pain, stiffness, or swelling
  • night blindness
  • overbright appearance of lights
  • redness of the skin
  • stomach distension or pain
  • swelling of the eyelids, face, lips, hands, or feet
  • trouble breathing or swallowing
  • tunnel vision

Get emergency help immediately if any of the following symptoms of overdose occur while taking doxylamine / pyridoxine:

Symptoms of overdose

Managing side effects (general information)

For healthcare professionals

Applies to doxylamine / pyridoxine: oral delayed release tablet, oral tablet extended release.

General adverse events

The most commonly reported side effects were somnolence, dizziness, dry mouth, and fatigue.[Ref]

Nervous system

Severe somnolence occurred when this drug was coadministered with central nervous system depressants (e.g., alcohol).

Anticholinergic effects may be worsened and prolonged with the concomitant use of MAO inhibitors.

Blurred vision, facial dyskinesia, faintness, headache, paresthesia, tremors, and/or vertigo may occur as a result of anticholinergic effects associated with antihistamines.[Ref]

Gastrointestinal

Dry mouth and dry throat occurred as a result of anticholinergic effects associated with antihistamines.[Ref]

Other

Acute labyrinthitis and tinnitus may occur as a result of anticholinergic effects associated with antihistamines.[Ref]

Psychiatric

Insomnia, irritability, nervousness, and/or toxic psychoses may occur as a result of anticholinergic effects associated with antihistamines.[Ref]

Dermatologic

Sweating may occur as a result of anticholinergic effects associated with antihistamines.[Ref]

Respiratory

Dry nose, nasal stuffiness, and thickening of bronchial secretions, and/or wheezing may occur as a result of anticholinergic effects associated with antihistamines.[Ref]

Hematologic

Agranulocytosis, hemolytic anemia, leukopenia, pancytopenia, and/or thrombocytopenia was rarely reported in patients taking antihistamines.[Ref]

Cardiovascular

Chest tightness may occur as a result of anticholinergic effects associated with antihistamines.[Ref]

Genitourinary

Dysuria and urinary retention may occur as a result of anticholinergic effects associated with antihistamines.[Ref]

Metabolic

Increased appetite and/or weight gain occurred in patients taking antihistamines.[Ref]

Ocular

Visual disturbances may occur as a result of anticholinergic effects associated with antihistamines.[Ref]

Hypersensitivity

Musculoskeletal

Chills may occur as a result of anticholinergic effects associated with antihistamines.[Ref]

Endocrine

Early menses may occur as a result of anticholinergic effects associated with antihistamines.[Ref]

References

1. Cerner Multum, Inc. "UK Summary of Product Characteristics."

2. (2013) "Product Information. Diclegis (doxylamine-pyridoxine)." Duchesnay USA Inc

3. (2013) "Product Information. Diclectin (doxylamine-pyridoxine)." Duchesnay Inc

Further information

Bonjesta side effects can vary depending on the individual. Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.

Note: Medication side effects may be underreported. If you are experiencing side effects that are not listed, submit a report to the FDA by following this guide.

Medical Disclaimer