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Bonjesta Side Effects

Generic Name: doxylamine / pyridoxine

Note: This document contains side effect information about doxylamine / pyridoxine. Some of the dosage forms listed on this page may not apply to the brand name Bonjesta.

For the Consumer

Applies to doxylamine / pyridoxine: oral tablet delayed release, oral tablet extended release

Along with its needed effects, doxylamine/pyridoxine may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.

Check with your doctor immediately if any of the following side effects occur while taking doxylamine / pyridoxine:

Incidence Not Known

  • Chest discomfort
  • decrease in the frequency of urination
  • decrease in urine volume
  • difficult or labored breathing
  • difficult or painful urination
  • fast, irregular, pounding, or racing heartbeat or pulse
  • swelling of the eyelids, face, lips, hands, or feet

Some side effects of doxylamine / pyridoxine may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:

More Common

  • Unusual drowsiness

For Healthcare Professionals

Applies to doxylamine / pyridoxine: oral delayed release tablet, oral tablet extended release


Postmarketing reports: Palpitation, tachycardia[Ref]


Postmarketing reports: Hyperhidrosis, pruritus, rash, maculo-papular rash[Ref]


Postmarketing reports: Abdominal distension, abdominal pain, constipation, diarrhea[Ref]


Postmarketing reports: Hypersensitivity[Ref]

Nervous system

Very common (10% or more): Somnolence (14.3%)

Postmarketing reports: Vertigo, dizziness, headache, migraines, paresthesia, psychomotor hyperactivity[Ref]


Postmarketing reports: Blurred vision, visual disturbances[Ref]


Postmarketing reports: Chest discomfort, fatigue, irritability, malaise[Ref]


Postmarketing reports: Anxiety, disorientation, insomnia, nightmares[Ref]


Postmarketing reports: Dysuria, urinary retention[Ref]


Postmarketing reports: Dyspnea[Ref]


1. "Product Information. Diclegis (doxylamine-pyridoxine)." Duchesnay USA Inc, Rosemont, PA.

Further information

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.

Some side effects may not be reported. You may report them to the FDA.