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B-3-50 Side Effects

Generic Name: niacin

Note: This page contains information about the side effects of niacin. Some of the dosage forms included on this document may not apply to the brand name B-3-50.

For the Consumer

Applies to niacin: oral capsule, oral capsule extended release, oral elixir, oral tablet, oral tablet extended release

In addition to its needed effects, some unwanted effects may be caused by niacin (the active ingredient contained in B-3-50). In the event that any of these side effects do occur, they may require medical attention.

Major Side Effects

You should check with your doctor immediately if any of these side effects occur when taking niacin:

Less common:
  • Darkening of urine
  • light gray-colored stools
  • loss of appetite
  • severe stomach pain
  • yellow eyes or skin

Minor Side Effects

Some of the side effects that can occur with niacin may not need medical attention. As your body adjusts to the medicine during treatment these side effects may go away. Your health care professional may also be able to tell you about ways to reduce or prevent some of these side effects. If any of the following side effects continue, are bothersome or if you have any questions about them, check with your health care professional:

Less common:
  • Abdominal or stomach pain
  • cough
  • diarrhea
  • feeling of warmth
  • flushing or redness of the skin, especially on the face and neck
  • headache
  • nausea or vomiting
  • rash or itching
  • runny nose
  • sneezing
  • stuffy nose
Incidence not known:
  • Dizziness or faintness
  • dryness of the skin
  • fever
  • frequent urination
  • joint pain
  • muscle aching or cramping
  • side, lower back, or stomach pain
  • swelling of the feet or lower legs
  • unusual thirst
  • unusual tiredness or weakness
  • unusually fast, slow, or irregular heartbeat

For Healthcare Professionals

Applies to niacin: compounding powder, oral capsule, oral capsule extended release, oral liquid, oral tablet, oral tablet extended release

Cardiovascular

Very common (10% or more): Flushing (i.e., warmth, redness, itching, and/or tingling) (up to 88%)
Frequency not reported: Tachycardia, palpitations, atrial fibrillation, other cardiac arrhythmias, syncope, hypotension, postural hypotension[Ref]

Dermatologic

Common (1% to 10%): Rash, pruritus
Frequency not reported: Sweating, skin burning sensation, maculopapular rash, dry skin
Postmarketing reports: Skin discoloration[Ref]

Gastrointestinal

Very common (10% or more): Diarrhea (up to 14%), nausea (up to 11%)
Common (1% to 10%): Vomiting
Frequency not reported: Peptic ulcers, eructation, flatulence[Ref]

Hematologic

Postmarketing reports: Slight reductions in platelet counts, prothrombin time prolonged[Ref]

Hypersensitivity

Postmarketing reports: Hypersensitivity reactions (e.g., anaphylaxis, angioedema, urticaria, flushing, dyspnea, tongue edema, larynx edema, face edema, peripheral edema, laryngismus, vesiculobullous rash)[Ref]

Hepatic

Postmarketing reports: Hepatitis, jaundice[Ref]

Metabolic

Frequency not reported: Decreased glucose tolerance, gout[Ref]

Musculoskeletal

Frequency not reported: Myalgia, myopathy[Ref]

Nervous system

Frequency not reported: Dizziness, syncope
Postmarketing reports: Migraine, asthenia, paresthesia[Ref]

Ocular

Postmarketing reports: Blurred vision, macular edema[Ref]

Psychiatric

Postmarketing reports: Insomnia, nervousness[Ref]

Other

Frequency not reported: Chills, edema[Ref]

Respiratory

Common (1% to 10%): Cough increased
Frequency not reported: Dyspnea[Ref]

References

1. "Product Information. Niacor (niacin)." Upsher-Smith Laboratories Inc, Minneapolis, MN.

2. "Product Information. Niacin (niacin)." 21st Century Healthcare Inc, Tempe, AZ.

Not all side effects for B-3-50 may be reported. You should always consult a doctor or healthcare professional for medical advice. Side effects can be reported to the FDA here.

Disclaimer: Every effort has been made to ensure that the information provided is accurate, up-to-date and complete, but no guarantee is made to that effect. In addition, the drug information contained herein may be time sensitive and should not be utilized as a reference resource beyond the date hereof. This material does not endorse drugs, diagnose patients, or recommend therapy. This information is a reference resource designed as supplement to, and not a substitute for, the expertise, skill , knowledge, and judgement of healthcare practitioners in patient care. The absence of a warning for a given drug or combination thereof in no way should be construed to indicate safety, effectiveness, or appropriateness for any given patient. Drugs.com does not assume any responsibility for any aspect of healthcare administered with the aid of materials provided. The information contained herein is not intended to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions, or adverse effects. If you have questions about the substances you are taking, check with your doctor, nurse, or pharmacist.

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