Atorvastatin / ezetimibe Side Effects
Medically reviewed by Drugs.com. Last updated on Jan 11, 2023.
Applies to atorvastatin / ezetimibe: oral tablet.
The more commonly reported adverse reactions have included increased ALT, increased AST, and musculoskeletal pain.[Ref]
Common (1% to 10%): ALT increased (5%), AST increased (4%)
Postmarketing reports: Hepatitis, cholelithiasis, cholecystitis, fatal and nonfatal hepatic failure[Ref]
Common (1% to 10%): Musculoskeletal pain (3.8 to 4%), arthralgia (3 to 6.9%), pain in extremity (2.7 to 6%), myalgia (3.5%), muscle spasms (3%), muscle weakness (2%)
Postmarketing reports: Myopathy/rhabdomyolysis, necrotizing myopathy (rarely), injury, poisoning and procedural complication, tendon rupture, myositis[Ref]
Common (1% to 10%): Diarrhea (4.1 to 6.8%), abdominal pain (3%), nausea (3 to 4%), dyspepsia (4.7%)[Ref]
Common (1% to 10%): Dizziness (2 to 6%), insomnia (3%), fatigue (2.4%)
Postmarketing reports: Headache, paraesthesia, peripheral neuropathy, amnesia, memory impairment, confusion, depression, dizziness[Ref]
Common (1% to 10%): Hyperkalemia (2%)[Ref]
Common (1% to 10%): Hot flushes (2%)[Ref]
Common (1% to 10%): Urinary tract infection (5.7%)[Ref]
Postmarketing reports: Thrombocytopenia, elevated creatine phosphokinase[Ref]
Postmarketing reports: Anaphylaxis, hypersensitivity reactions[Ref]
Common (1% to 10%): Influenza (2%)[Ref]
Common (1% to 10%): Coughing (2 to 3%), bronchitis (2%), sinusitis (2 to 2.8%), upper respiratory tract infection (4.3%), nasopharyngitis (up to 8.3%), pharyngolaryngeal pain (up to 2.3%)
Postmarketing reports: Interstitial lung disease[Ref]
Postmarketing reports: Fatigue
Postmarketing reports: Angioedema, bullous rashes (including erythema multiforme, Stevens-Johnson syndrome, and toxic epidermal necrolysis), rash, urticaria[Ref]
More about atorvastatin / ezetimibe
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- Drug class: antihyperlipidemic combinations
Related treatment guides
1. Cerner Multum, Inc. "Australian Product Information." O 0
2. "Product Information. Liptruzet (atorvastatin-ezetimibe)." Merck & Co., Inc (2013):
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.
Some side effects may not be reported. You may report them to the FDA.