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Ajovy Side Effects

Generic name: fremanezumab

Medically reviewed by Philip Thornton, DipPharm. Last updated on Dec 21, 2023.

Note: This document contains side effect information about fremanezumab. Some dosage forms listed on this page may not apply to the brand name Ajovy.

Applies to fremanezumab: subcutaneous solution.

Serious side effects of Ajovy

Along with its needed effects, fremanezumab (the active ingredient contained in Ajovy) may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.

Check with your doctor immediately if any of the following side effects occur while taking fremanezumab:

More common

Other side effects of Ajovy

Some side effects of fremanezumab may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects.

Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:

More common

For Healthcare Professionals

Applies to fremanezumab: subcutaneous solution.


The most commonly reported adverse reaction during clinical trials was injection site reactions.[Ref]


Very common (10% or more): Injection site reactions (up to 45%)[Ref]

Injection site reactions included injection site pain, induration, erythema, and pruritus.[Ref]


Uncommon (0.1% to 1%): Hypersensitivity reactions

Postmarketing reports: Anaphylaxis, angioedema


Common (1% to 10%): Anti-Drug-Antibodies[Ref]

Frequently asked questions


1. EMEA. European Medicines Agency. EPARs. European Union Public Assessment Reports. 2007.

2. Product Information. Ajovy (fremanezumab). Nephroceuticals. 2018.

Further information

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.

Some side effects may not be reported. You may report them to the FDA.