Ajovy Injection Dosage

Recommended Dosage

Adults

The recommended dosage in adults for the preventive treatment of migraine is administered by subcutaneous injection as one of the following options:

• 225 mg monthly, or
• 675 mg every 3 months (quarterly), which is administered as three consecutive subcutaneous injections of 225 mg each.

When switching dosage options, administer the first dose of the new regimen on the next scheduled date of administration.

Pediatric Patients who are 6 to 17 Years of Age and who Weigh 45 kg or More:

​The recommended dosage for the preventive treatment of episodic migraine in pediatric patients who are 6 to 17 years of age and who weigh 45 kg or more is administered by subcutaneous injection as follows:

• ​225 mg monthly.

​AJOVY is not approved in pediatric patients weighing less than 45 kg because of the lack of an appropriate strength presentation.

Missed Dose

If a dose of AJOVY is missed, administer as soon as possible. Thereafter, AJOVY can be scheduled from the date of the last dose.

Important Administration Instructions

AJOVY is for subcutaneous use only.

​AJOVY may be administered by healthcare providers, patients 13 years of age and older, and/or caregivers. In pediatric patients 6 to 12 years of age, AJOVY must be administered by a healthcare provider or adult caregiver. Prior to use, provide proper training to patients and/or caregivers on the preparation and administration of AJOVY prefilled syringe, including aseptic technique:

• Remove AJOVY from the refrigerator. Prior to use, allow AJOVY to sit at room temperature for 30 minutes protected from direct sunlight. Do not warm by using a heat source such as hot water or a microwave. Do not use AJOVY if it has been at room temperature for 7 days or longer.
• Follow aseptic injection technique every time AJOVY is administered.
• Inspect AJOVY for particles or discoloration prior to administration. Do not use if the solution is cloudy, discolored, or contains particles.
• Administer AJOVY by subcutaneous injection into areas of the abdomen, thigh, or upper arm that are not tender, bruised, red, or indurated. For multiple injections, you may use the same body site, but not the exact location of the previous injection.
• Do not co-administer AJOVY with other injectable drugs at the same injection site.