Skip to main content

Aclidinium / formoterol Side Effects

Medically reviewed by Last updated on Apr 7, 2022.

For the Consumer

Applies to aclidinium / formoterol: inhalation aerosol powder

Side effects requiring immediate medical attention

Along with its needed effects, aclidinium/formoterol may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.

Check with your doctor immediately if any of the following side effects occur while taking aclidinium / formoterol:

More common

  • Body aches or pain
  • chills
  • cough
  • difficulty in breathing
  • ear congestion
  • fever
  • headache
  • loss of voice
  • runny or stuffy nose
  • sneezing
  • sore throat
  • unusual tiredness or weakness

Less common

  • Bladder pain
  • bloody or cloudy urine
  • diarrhea
  • difficult, burning, or painful urination
  • frequent urge to urinate
  • general feeling of discomfort or illness
  • joint pain
  • loss of appetite
  • lower back or side pain
  • muscle aches and pains
  • nausea
  • pain or tenderness around the eyes and cheekbones
  • shivering
  • sweating
  • tightness of the chest
  • trouble sleeping
  • vomiting

Get emergency help immediately if any of the following symptoms of overdose occur while taking aclidinium / formoterol:

Symptoms of overdose

Side effects not requiring immediate medical attention

Some side effects of aclidinium / formoterol may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects.

Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:

Less common

  • Back, arm, or leg pain
  • bone pain
  • difficulty in moving
  • dry mouth
  • mouth or throat pain
  • muscle stiffness
  • toothache

For Healthcare Professionals

Applies to aclidinium / formoterol: inhalation powder


Uncommon (0.1% to 1%): Tachycardia, electrocardiogram QTc prolonged, palpitations, blood pressure increased[Ref]


Uncommon (0.1% to 1%): Rash, pruritus[Ref]


Common (1% to 10%): Diarrhea, nausea, dry mouth, tooth abscess[Ref]


Uncommon (0.1% to 1%): Urinary retention, urinary tract infection[Ref]


Rare (less than 0.1%): Hypersensitivity

Frequency not reported: Angioedema[Ref]


Uncommon (0.1% to 1%): Hyperglycaemia, hypokalemia[Ref]


Common (1% to 10%): Myalgia, muscle spasms, blood creatinine phosphokinase increased[Ref]

Nervous system

Common (1% to 10%): Headache, dizziness, tremor

Uncommon (0.1% to 1%): Dysgeusia[Ref]


Uncommon (0.1% to 1%): Blurred vision[Ref]


Common (1% to 10%): Edema peripheral[Ref]


Common (1% to 10%): Anxiety, insomnia

Uncommon (0.1% to 1%): Agitation[Ref]


Common (1% to 10%): Cough, nasopharyngitis, sinusitis

Uncommon (0.1% to 1%): Dysphonia, throat irritation

Rare (less than 0.1%): Bronchospasm, including paradoxical[Ref]


1. Cerner Multum, Inc. "UK Summary of Product Characteristics." O 0

Further information

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.

Some side effects may not be reported. You may report them to the FDA.