Aclidinium / Formoterol Side Effects

Medically reviewed by Drugs.com. Last updated on Oct 20, 2024.

Applies to aclidinium / formoterol: inhalation aerosol powder.

Precautions

It is very important that your doctor check your progress at regular visits to see if this medicine is working properly and to check for any unwanted effects.

Tell your doctor about other medicines you are using for COPD. Follow your doctor's instructions on how you should take your medicine.

This medicine should not be used if you are having a COPD attack, or if symptoms of a COPD attack has already started. Your doctor will prescribe another medicine for you to use in case of an acute attack. If the other medicine does not work as well, tell your doctor right away.

This medicine should not be used together with similar inhaled medicines, such as arformoterol (Brovana®), formoterol (Foradil®, Perforomist®), glycopyrrolate (Robinul®), indacaterol (Onbrez®), ipratropium (Atrovent, Apovent®, Ipraxa®, Rinatec®), olodaterol (Striverdi® Respimat®), salmeterol (Serevent®), tiotropium (Spiriva®, Braltus®), umeclidinium (Incruse™ Ellipta®), or vilanterol.

This medicine may increase the chance of asthma-related problems. Be sure to read about these risks in the Medication Guide and talk to your doctor or pharmacist about any questions or concerns that you have.

This medicine may cause paradoxical bronchospasm, which means your breathing or wheezing will get worse. Paradoxical bronchospasm may be life-threatening. Check with your doctor right away if you have coughing, difficulty breathing, shortness of breath, or wheezing after using this medicine.

This medicine may cause serious allergic reactions, including anaphylaxis and angioedema, which can be life-threatening and require immediate medical attention. Call your doctor right away if you have a rash, itching, trouble breathing, trouble swallowing, or any swelling of your hands, face, mouth, or throat while you are using this medicine.

This medicine may increase your risk for heart and blood vessel problems, including changes in heart rhythm. Check with your doctor right away if you have dizziness, fainting spells, severe tiredness, chest pain, trouble with breathing, sudden or severe headache, or fast or irregular heartbeat.

Check with your doctor right away if blurred vision, difficulty in reading, or any other change in vision occurs during or after treatment. Your doctor may want your eyes be checked by an ophthalmologist (eye doctor).

This medicine may affect blood sugar and potassium levels. If you have heart disease or diabetes and notice a change in the results of your blood or urine sugar or potassium tests, check with your doctor.

Do not take other medicines unless they have been discussed with your doctor. This includes prescription or nonprescription (over-the-counter [OTC]) medicines and herbal or vitamin supplements.

Serious side effects

Along with its needed effects, aclidinium / formoterol may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.

Check with your doctor immediately if any of the following side effects occur while taking aclidinium / formoterol:

Get emergency help immediately if any of the following symptoms of overdose occur while taking aclidinium / formoterol:

Symptoms of overdose

• blurred vision
• dizziness
• fast, pounding, or irregular heartbeat or pulse
• headache
• muscle spasms
• nervousness
• pounding in the ears
• slow heartbeat
• tremor

Other side effects

Some side effects of aclidinium / formoterol may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects.

Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:

For healthcare professionals

Applies to aclidinium / formoterol: inhalation powder.

Cardiovascular adverse events

• Uncommon (0.1% to 1%): Tachycardia, electrocardiogram QTc prolonged, palpitations, blood pressure increased^[Ref]

Dermatologic

• Uncommon (0.1% to 1%): Rash, pruritus^[Ref]

Gastrointestinal

• Common (1% to 10%): Diarrhea, nausea, dry mouth, tooth abscess^[Ref]

Genitourinary

• Uncommon (0.1% to 1%): Urinary retention, urinary tract infection^[Ref]

Hypersensitivity

• Rare (less than 0.1%): Hypersensitivity
• Frequency not reported: Angioedema^[Ref]

Metabolic

• Uncommon (0.1% to 1%): Hyperglycaemia, hypokalemia^[Ref]

Musculoskeletal

• Common (1% to 10%): Myalgia, muscle spasms, blood creatinine phosphokinase increased^[Ref]

Nervous system

• Common (1% to 10%): Headache, dizziness, tremor
• Uncommon (0.1% to 1%): Dysgeusia^[Ref]

Ocular

• Uncommon (0.1% to 1%): Blurred vision^[Ref]

Other

• Common (1% to 10%): Edema peripheral^[Ref]

Psychiatric

• Common (1% to 10%): Anxiety, insomnia
• Uncommon (0.1% to 1%): Agitation^[Ref]

Respiratory

• Common (1% to 10%): Cough, nasopharyngitis, sinusitis
• Uncommon (0.1% to 1%): Dysphonia, throat irritation
• Rare (less than 0.1%): Bronchospasm, including paradoxical^[Ref]

See also:

Further information

Aclidinium/formoterol side effects can vary depending on the individual. Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.

Note: Medication side effects may be underreported. If you are experiencing side effects that are not listed, submit a report to the FDA by following this guide.

Medical Disclaimer