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12 Hour Nasal Side Effects

Generic name: oxymetazoline nasal

Medically reviewed by Drugs.com. Last updated on Aug 11, 2022.

Note: This document contains side effect information about oxymetazoline nasal. Some dosage forms listed on this page may not apply to the brand name 12 Hour Nasal.

Applies to oxymetazoline nasal: nasal spray.

Serious side effects of 12 Hour Nasal

Along with its needed effects, oxymetazoline nasal (the active ingredient contained in 12 Hour Nasal) may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.

Check with your doctor immediately if any of the following side effects occur while taking oxymetazoline nasal:

Other side effects of 12 Hour Nasal

Some side effects of oxymetazoline nasal may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects.

Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:

  • Burning, dryness, or stinging inside of nose
  • sneezing

For Healthcare Professionals

Applies to oxymetazoline nasal: nasal solution, nasal spray.

Cardiovascular

Very rare (less than 0.01%): Tachycardia, palpitations, increased blood pressure[Ref]

Gastrointestinal

Very rare (less than 0.01%): Nausea[Ref]

General

The most commonly reported side effects were discomfort or irritation in the nose, mouth or throat, and sneezing.[Ref]

Nervous system

Very rare (less than 0.01%): Insomnia, nervousness, tremor, anxiety, restlessness, irritability, headache[Ref]

Ocular

Rare (less than 0.1%): Eye irritation, dryness, discomfort/redness[Ref]

Respiratory

Rare (less than 0.1%): Discomfort or irritation in the nose, mouth or throat, sneezing

Frequency not reported: Rhinitis medicamentosa (after prolonged or heavy use)[Ref]

References

1. Cerner Multum, Inc. "UK Summary of Product Characteristics." O 0

2. Cerner Multum, Inc. "Australian Product Information." O 0

3. "Product Information. Afrin (oxymetazoline nasal)." Schering-Plough (2001):

Further information

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.

Some side effects may not be reported. You may report them to the FDA.