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Generic Name: dexamethasone intravitreal implant (DEX a METH a sone IN tra VIT ree al IM plant)
Brand Names: Ozurdex

What is Ozurdex?

Ozurdex implants contain dexamethasone, a corticosteroid used to treat inflammation.

Ozurdex is an implant injected into the eye to treat swelling that may occur when there is a blockage of certain blood vessels in your eyes.

Ozurdex is also used to treat posterior uveitis, inflammation that affects the back part of the eye.

Ozurdex may also be used for purposes not listed in this medication guide.

Important information

Ozurdex is a steroid implant injected into the eye to treat swelling that may occur when there is a blockage of certain blood vessels in your eyes.

You should not receive an Ozurdex implant if you have an eye infection, advanced glaucoma, had certain types of artificial lens implanted in your eye, or a history of eye ulcer, surgery, or wound that has injured or removed the lens in your eye.

Ozurdex can increase your risk of certain eye problems. Call your doctor at once if you have vision changes, eye pain or redness, increased sensitivity to light, or seeing halos around lights.

Before receiving Ozurdex?

You should not receive Ozurdex if you are allergic to dexamethasone, or if you have:

  • an eye infection;

  • advanced glaucoma;

  • certain types of artificial lens implanted in your eye; or

  • a history of eye ulcer, surgery, or wound that has injured or removed the lens in your eye.

To make sure Ozurdex is safe for you, tell your doctor if you have ever had herpes infection of the eyes.

FDA pregnancy category C. It is not known whether Ozurdex will harm an unborn baby. Tell your doctor if you are pregnant or plan to become pregnant.

See also: Pregnancy and breastfeeding warnings (in more detail)

It is not known whether dexamethasone passes into breast milk or if it could harm a nursing baby. Tell your doctor if you are breast-feeding a baby.

How is Ozurdex given?

Ozurdex will be injected into your eye by healthcare professional in a clinic setting.

After the implant is put in place, you will be watched closely for any swelling, inflammation, or increased pressure in your eye.

See also: Dosage Information (in more detail)

What happens if I miss a dose?

Since Ozurdex is a surgical implant, it does not have a daily dosing schedule.

What happens if I overdose?

Since the Ozurdex contains a specific amount of the medication, you are not likely to receive an overdose.

What should I avoid?

This medication may cause blurred vision. Be careful if you drive or do anything that requires you to be able to see clearly.

Ozurdex side effects

Get emergency medical help if you have any signs of an allergic reaction to Ozurdex: hives; difficult breathing; swelling of your face, lips, tongue, or throat.

Call your doctor at once if you have:

  • vision problems, eye pain, or seeing halos around lights;

  • eye redness, increased sensitivity of your eyes to light; or

  • vision changes.

Common Ozurdex side effects may include blurred vision.

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

See also: Side effects (in more detail)

What other drugs will affect Ozurdex?

It is not likely that other drugs you take orally or inject will have an effect on dexamethasone used in the eyes. But many drugs can interact with each other. Tell each of your healthcare providers about all medicines you use, including prescription and over-the-counter medicines, vitamins, and herbal products.

Where can I get more information?

  • Your doctor or pharmacist can provide more information about Ozurdex.
  • Remember, keep this and all other medicines out of the reach of children, never share your medicines with others, and use this medication only for the indication prescribed.
  • Disclaimer: Every effort has been made to ensure that the information provided by Cerner Multum, Inc. ('Multum') is accurate, up-to-date, and complete, but no guarantee is made to that effect. Drug information contained herein may be time sensitive. Multum information has been compiled for use by healthcare practitioners and consumers in the United States and therefore Multum does not warrant that uses outside of the United States are appropriate, unless specifically indicated otherwise. Multum's drug information does not endorse drugs, diagnose patients or recommend therapy. Multum's drug information is an informational resource designed to assist licensed healthcare practitioners in caring for their patients and/or to serve consumers viewing this service as a supplement to, and not a substitute for, the expertise, skill, knowledge and judgment of healthcare practitioners. The absence of a warning for a given drug or drug combination in no way should be construed to indicate that the drug or drug combination is safe, effective or appropriate for any given patient. Multum does not assume any responsibility for any aspect of healthcare administered with the aid of information Multum provides. The information contained herein is not intended to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions, or adverse effects. If you have questions about the drugs you are taking, check with your doctor, nurse or pharmacist.

Copyright 1996-2018 Cerner Multum, Inc. Version: 4.01. Revision Date: 2017-02-02, 12:53:03 PM.