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Generic Name: valbenazine (val BEN a zeen)
Brand Name: Ingrezza

Medically reviewed by on May 6, 2019 – Written by Cerner Multum

What is valbenazine?

Valbenazine is used to treat symptoms of tardive dyskinesia, a nervous system disorder. Tardive dyskinesia causes repetitive uncontrolled muscle movements, usually in the face (chewing, lip smacking, frowning, tongue movement, blinking or eye movement). Valbenazine is not a permanent cure for this condition.

Valbenazine may also be used for purposes not listed in this medication guide.

Important Information

Do not breast-feed while using valbenazine and for at least 5 days after your last dose.

Before taking this medicine

You should not use valbenazine if you are allergic to it.

Tell your doctor if you have ever had:

It is not known whether this medicine will harm an unborn baby. Tell your doctor if you are pregnant or plan to become pregnant.

Do not breast-feed while using this medicine and for at least 5 days after your last dose.

Valbenazine is not approved for use by anyone younger than 18 years old.

How should I take valbenazine?

Follow all directions on your prescription label and read all medication guides or instruction sheets. Your doctor may occasionally change your dose. Use the medicine exactly as directed.

You may take valbenazine with or without food.

Your heart function may need to be checked using an electrocardiograph or ECG (sometimes called an EKG).

Do not stop taking valbenazine without first asking your doctor.

Store at room temperature away from moisture and heat.

What happens if I miss a dose?

Take the medicine as soon as you can, but skip the missed dose if it is almost time for your next dose. Do not take two doses at one time.

What happens if I overdose?

Seek emergency medical attention or call the Poison Help line at 1-800-222-1222.

What should I avoid while taking valbenazine?

Avoid driving or hazardous activity until you know how valbenazine will affect you. Dizziness or drowsiness can cause falls, accidents, or severe injuries.

Valbenazine side effects

Get emergency medical help if you have signs of an allergic reaction: hives; difficult breathing; swelling of your face, lips, tongue, or throat.

Call your doctor at once if you have:

  • extreme drowsiness;

  • fast, slow, or uneven heartbeats;

  • pounding heartbeats or fluttering in your chest;

  • shortness of breath; or

  • a light-headed feeling, like you might pass out.

Common side effects may include:

  • headache, dizziness, drowsiness;

  • problems with balance or coordination;

  • dry mouth;

  • feeling restless;

  • constipation; or

  • blurred vision.

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

Valbenazine dosing information

Usual Adult Dose for Tardive Dyskinesia:

-Initial Dose: 40 mg orally once a day
-Maintenance Dose: Increase to 80 mg orally once a day after one week at the initial dose; however, continuation of the initial dose may be considered for some patients.

Comments: Administer with or without food.

Use: Treatment of tardive dyskinesia.

What other drugs will affect valbenazine?

Other drugs may affect valbenazine, including prescription and over-the-counter medicines, vitamins, and herbal products. Tell your doctor about all your current medicines and any medicine you start or stop using.

Further information

Remember, keep this and all other medicines out of the reach of children, never share your medicines with others, and use this medication only for the indication prescribed.

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.

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