Generic Name: scopolamine (oral) (skoe PAH lah meen)
Brand Name: Maldemar
What is scopolamine?
Scopolamine reduces the secretions of certain organs in the body, such as the stomach and intestines. Scopolamine also decreases nerve signals that trigger your stomach to vomit.
Scopolamine is used to prevent nausea and vomiting caused by motion sickness or from anesthesia given during surgery.
Scopolamine is also used to treat certain stomach or intestinal problems, muscle spasms, and Parkinson-like conditions.
Scopolamine may also be used for purposes not listed in this medication guide.
What is the most important information I should know about scopolamine?
You should not use scopolamine if you have narrow-angle glaucoma, a blockage in your intestines, a severe breathing disorder, or if you are unable to urinate.
What should I discuss with my healthcare provider before taking scopolamine?
You should not use this medicine if you are allergic to scopolamine or similar medications such as methscopolamine or hyoscyamine, or if you have:
a blockage in your intestines;
a severe breathing disorder; or
if you are unable to urinate.
To make sure scopolamine is safe for you, tell your doctor if you have:
an enlarged prostate, bladder obstruction, or urination problems;
problems with your esophagus, stomach, or intestines;
heart disease, high blood pressure;
coronary artery disease (hardened arteries);
asthma or other breathing problems;
a drug allergy; or
a history of head injury or brain tumor.
It is not known whether this medicine will harm an unborn baby. Tell your doctor if you are pregnant or plan to become pregnant.
It is not known whether scopolamine passes into breast milk or if it could harm a nursing baby. Tell your doctor if you are breast-feeding a baby.
Scopolamine is not approved for use by anyone younger than 6 months.
How should I take scopolamine?
Follow all directions on your prescription label. Do not take this medicine in larger or smaller amounts or for longer than recommended.
Take this medicine with a full glass of water.
You may take scopolamine with or without food.
If you take scopolamine to treat a Parkinson-like condition, you should not stop using this medicine suddenly. Stopping suddenly may make your condition worse.
Store at room temperature away from moisture and heat.
What happens if I miss a dose?
Since scopolamine is sometimes used only when needed, you may not be on a dosing schedule. If you are on a schedule, use the missed dose as soon as you remember. Skip the missed dose if it is almost time for your next scheduled dose. Do not use extra medicine to make up the missed dose.
What happens if I overdose?
Seek emergency medical attention or call the Poison Help line at 1-800-222-1222. An overdose of scopolamine can be fatal, especially to a child.
Overdose symptoms may include fever, warmth, vomiting, feeling restless or excited, confusion, hallucinations, weak or shallow breathing, or seizure (convulsions).
What should I avoid while using scopolamine?
This medicine may cause blurred vision and may impair your thinking or reactions. Be careful if you drive or do anything that requires you to be alert and able to see clearly.
Avoid becoming overheated or dehydrated during exercise and in hot weather. Scopolamine can decrease sweating and you may be more prone to heat stroke.
Scopolamine can dilate your pupils, making your eyes more sensitive to light. You may need to wear sunglasses even while indoors.
Drinking alcohol with this medicine can cause side effects.
Scopolamine side effects
Get emergency medical help if you have signs of an allergic reaction: hives; difficult breathing; swelling of your face, lips, tongue, or throat.
Call your doctor or tell your caregivers at once if you have:
little or no urinating;
fast or pounding heartbeats;
confusion, paranoia; or
Common side effects may include:
dry mouth, increased thirst;
painful or difficult urination;
feeling restless; or
blurred vision, dilated pupils, your eyes may be more sensitive to light.
Side effects may be more likely in older adults.
This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.
See also: Side effects (in more detail)
Scopolamine dosing information
Usual Adult Dose for Nausea/Vomiting:
General antiemetic use: 0.3 to 0.65 mg administered IV, intramuscularly or subcutaneously every 6 to 8 hours as needed.
Post-operative nausea and vomiting use: apply one scopolamine 1.5 mg transdermal disc behind the ear the evening before the scheduled surgery. The disc should remain in place for 24 hours after surgery before discarding.
If using scopolamine transdermal on an obstetrics patient, apply the disc one hour prior to scheduled Cesarean section to limit exposure to the infant.
Usual Adult Dose for Motion Sickness:
Apply one scopolamine 1.5 mg transdermal disc behind the ear at least 4 hours prior to exposure every 3 days as needed.
Usual Adult Dose for Parkinsonian Tremor:
0.4 to 0.8 mg orally every 8 hours as needed.
Usual Pediatric Dose for Nausea/Vomiting:
1 to 12 years: 6 mcg/kg/dose (maximum dose: 0.3 mg/dose) administered IV, IM or subcutaneous every 6 to 8 hours as needed.
Usual Pediatric Dose for Motion Sickness:
Greater than 12 years: apply one scopolamine 1.5 mg transdermal disc behind the ear at least 4 hours prior to exposure every 3 days as needed.
What other drugs will affect scopolamine?
Other drugs may interact with scopolamine, including prescription and over-the-counter medicines, vitamins, and herbal products. Tell each of your health care providers about all medicines you use now and any medicine you start or stop using.
More about scopolamine
Related treatment guides
Where can I get more information?
- Your pharmacist can provide more information about scopolamine.
- Remember, keep this and all other medicines out of the reach of children, never share your medicines with others, and use this medication only for the indication prescribed.
- Disclaimer: Every effort has been made to ensure that the information provided by Cerner Multum, Inc. ('Multum') is accurate, up-to-date, and complete, but no guarantee is made to that effect. Drug information contained herein may be time sensitive. Multum information has been compiled for use by healthcare practitioners and consumers in the United States and therefore Multum does not warrant that uses outside of the United States are appropriate, unless specifically indicated otherwise. Multum's drug information does not endorse drugs, diagnose patients or recommend therapy. Multum's drug information is an informational resource designed to assist licensed healthcare practitioners in caring for their patients and/or to serve consumers viewing this service as a supplement to, and not a substitute for, the expertise, skill, knowledge and judgment of healthcare practitioners. The absence of a warning for a given drug or drug combination in no way should be construed to indicate that the drug or drug combination is safe, effective or appropriate for any given patient. Multum does not assume any responsibility for any aspect of healthcare administered with the aid of information Multum provides. The information contained herein is not intended to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions, or adverse effects. If you have questions about the drugs you are taking, check with your doctor, nurse or pharmacist.
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